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Diffusion MRI (dMRI) is a critical non-invasive technique to estimate fiber orientation distribution (FOD) for characterizing white matter integrity. Estimating FOD from single-shell low angular resolution dMRI (LAR-FOD) is limited by…
It is highly desirable to know how uncertain a model's predictions are, especially for models that are complex and hard to understand as in deep learning. Although there has been a growing interest in using deep learning methods in…
The fully automated and relatively accurate method of brain tissues segmentation on T2-weighted magnetic resonance perfusion images is proposed. Segmentation with this method provides a possibility to obtain perfusion region of interest on…
Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of…
Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…
Diffusion weighted imaging techniques permit us to infer microstructural detail in biological tissue in vivo and noninvasively. Modern sequences are based on advanced diffusion encoding schemes, allowing probing of more revealing measures…
We propose a new method, Patch-CNN, for diffusion tensor (DT) estimation from only six-direction diffusion weighted images (DWI). Deep learning-based methods have been recently proposed for dMRI parameter estimation, using either voxel-wise…
Our understanding of the human connectome is fundamentally limited by the resolution of diffusion MR images. Reconstructing a connectome's constituent neural pathways with tractography requires following a continuous field of fiber…
Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…
Biophysical modeling is the mediator of evaluating the cellular structure of biological tissues using diffusion-weighted MRI. It is however the bottleneck of microstructural MRI. Beyond the complexity of diffusion, the current development…
Tractography traces the peak directions extracted from fiber orientation distribution (FOD) suffering from ambiguous spatial correspondences between diffusion directions and fiber geometry, which is prone to producing erroneous tracks while…
Diffusion kurtosis imaging is an extension of diffusion tensor imaging that provides scientifically and clinically valuable information about brain tissue microstructure but suffers from poor robustness to noise, especially in voxels…
Diffusion-weighted imaging (DWI) in the female breast is a magnetic resonance imaging (MRI) technique, which may potentially replace or effectively complement both x-ray mammography and contrast-enhanced MR mammography. To further improve…
In this manuscript, we are concerned with data generated from a diffusion tensor imaging (DTI) experiment. The goal is to parameterize manifold-like white matter tracts, such as the corpus callosum, using principal surfaces. We approach the…
Diffusion-weighted MR imaging (DWI) is the only method we currently have to measure connections between different parts of the human brain in vivo. To elucidate the structure of these connections, algorithms for tracking bundles of axonal…
Purpose: Diffusion Magnetic Resonance Imaging (dMRI) is confounded by its long acquisition duration, thereby thwarting the detection of rapid microstructural changes, especially when diffusivity variations are accompanied by rapid changes…
Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…
Diffusion Magnetic Resonance Imaging (DMRI) is the only non-invasive imaging technique which is able to detect the principal directions of water diffusion as well as neurites density in the human brain. Exploiting the ability of Spherical…
Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion…
White matter structures composed of myelinated axons in the living human brain are primarily studied by diffusion-weighted MRI (dMRI). These long-range projections are typically characterized in a two-step process: dMRI is used to estimate…