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Proteins can combine into functional elements in living cells or self-assemble into unwanted structures in a number of diseases. The resulting aggregates often display filamentous morphologies across a large range of protein shapes and…

Soft Condensed Matter · Physics 2026-05-18 Elena N. Govorun , Martin Lenz

The phenomenon of synchronization occurs universally across the natural sciences and provides critical insight into the behavior of coupled nonlinear dynamical systems. It also offers a powerful approach to robust frequency or temporal…

Self-assembly of proteins is a biological phenomenon which gives rise to spontaneous formation of amyloid fibrils or polymers. The starting point of this phase, called nucleation exhibits an important variability among replicated…

Biomolecules · Quantitative Biology 2016-03-22 Marie Doumic , Sarah Eugene , Philippe Robert

Synchronization is of importance in both fundamental and applied physics, but their demonstration at the micro/nanoscale is mainly limited to low-frequency oscillations like mechanical resonators. Here, we report the synchronization of two…

Optics · Physics 2019-07-09 Da Xu , Zi-Zhao Han , Yu-Kun Lu , Qihuang Gong , Cheng-Wei Qiu , Gang Chen , Yun-Feng Xiao

Recent advances in computational power and simulation programs finally delivered the first examples of reversible folding for small proteins with an all-atom description. But having at hand the atomistic details of the process did not lead…

Biological Physics · Physics 2013-04-23 Ganna Berezovska , Diego Prada-Gracia , Francesco Rao

We show that spontaneous density segregation in dense systems of aligning circle swimmers is a condensation phenomenon at odds with the phase separation scenarios usually observed in two-dimensional active matter. The condensates, which…

Soft Condensed Matter · Physics 2024-12-20 Yujia Wang , Bruno Ventéjou , Hugues Chaté , Xia-qing Shi

Synchronization of non-identical oscillators coupled through complex networks is an important example of collective behavior. It is interesting to ask how the structural organization of network interactions influences this process. Several…

Adaptation and Self-Organizing Systems · Physics 2017-09-13 Lia Papadopoulos , Jason Kim , Jurgen Kurths , Danielle S. Bassett

Synchronization is a ubiquitous phenomenon in complex systems. The Kuramoto model serves as a paradigmatic framework for understanding how coupled oscillators achieve collective rhythm. Conventional approaches focus on pairwise…

Adaptation and Self-Organizing Systems · Physics 2026-03-16 Zheng Wang , Jinjie Zhu , Xianbin Liu

Pattern formation and the mechanics of a mixture of actin filaments and myosin motors that is confined by a rigid membrane is investigated. By using a coarse-grained molecular dynamics model, we demonstrate that the competition between the…

Soft Condensed Matter · Physics 2023-04-12 Mitsusuke Tarama , Tatsuo Shibata

A fundamental understanding of synchronized behavior in multi-agent systems can be acquired by studying analytically tractable Kuramoto models. However, such models typically diverge from many real systems whose dynamics evolve under…

Adaptation and Self-Organizing Systems · Physics 2021-07-28 Keith A. Wiley , Peter J. Mucha , Danielle S. Bassett

Natural protein sequences somehow encode the structural forms that these molecules adopt. Recent developments in structure-prediction are agnostic to the mechanisms by which proteins fold and represent them as static objects. However, the…

Biomolecules · Quantitative Biology 2025-05-26 Ezequiel A. Galpern , Federico Caamaño , Diego U. Ferreiro

Amyloid fibrillation is a protein self-assembly phenomenon that is intimately related to well-known human neurodegenerative diseases. During the past few decades, striking advances have been achieved in our understanding of the physical…

Biomolecules · Quantitative Biology 2017-09-06 Liu Hong , Chiu Fan Lee , Ya Jing Huang

We investigate the connection between the dynamics of synchronization and the modularity on complex networks. Simulating the Kuramoto's model in complex networks we determine patterns of meta-stability and calculate the modularity of the…

Disordered Systems and Neural Networks · Physics 2009-11-11 Alex Arenas , Albert Diaz-Guilera

The folding of a protein towards its native state is a rather complicated process. However there are empirical evidences that the folding time correlates with the contact order, a simple measure of the spatial organisation of the native…

Soft Condensed Matter · Physics 2017-12-06 Marco Baiesi , Enzo Orlandini , Flavio Seno , Antonio Trovato

In the framework of a lattice-model study of protein folding, we investigate the interplay between designability, thermodynamic stability, and kinetics. To be ``protein-like'', heteropolymers must be thermodynamically stable, stable against…

Statistical Mechanics · Physics 2009-10-31 Régis Mélin , Hao Li , Ned S. Wingreen , Chao Tang

In this work we study the synchronization of Kuramoto oscillators driven by external forces in complex modular networks. The motivation is the neuronal dynamics that takes place during information processing in the neural cortex. The neuron…

Adaptation and Self-Organizing Systems · Physics 2020-04-02 Carolina Arruda Moreira

Synchronization commonly occurs in many natural and man-made systems, from neurons in the brain to cardiac cells to power grids to Josephson junction arrays. Transitions to or out of synchrony for coupled oscillators depend on several…

Adaptation and Self-Organizing Systems · Physics 2018-05-10 Hui Wu , Mukesh Dhamala

A model system inspired by recent experiments on the dynamics of a folded protein under the influence of a sinusoidal force is investigated and found to replicate many of the response characteristics of such a system. The essence of the…

Soft Condensed Matter · Physics 2015-09-30 Craig Fogle , Joseph Rudnick , David Jasnow

Nonlinear oscillations and synchronisation phenomena are ubiquitous in nature. We study the synchronization of self oscillating magneto-optically trapped cold atoms to a weak external driving. The oscillations arise from a dynamical…

Atomic Physics · Physics 2018-04-09 Hermanni Heimonen , Leong Chuan Kwek , Robin Kaiser , Guillaume Labeyrie

A Newton's cradle is a device that demonstrates conservation of momentum using a series of identical colliding pendula. Despite being a famous example that demonstrates the concept of momentum conservation, extensive analysis of the system…

Classical Physics · Physics 2024-02-13 Minseok Lee , Seokchan Hong