Related papers: Airflow in a Multiscale Subject-Specific Breathing…
Accurately and precisely characterizing the morphology of small pulmonary structures from Computed Tomography (CT) images, such as airways and vessels, is becoming of great importance for diagnosis of pulmonary diseases. The smaller…
We propose a cascaded 3D diffusion model framework to synthesize high-fidelity 3D PET/CT volumes directly from demographic variables, addressing the growing need for realistic digital twins in oncologic imaging, virtual trials, and…
The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…
Chronic Obstructive Pulmonary Disorder (COPD) is a prevalent respiratory disease that significantly impacts the quality of life of affected individuals. This paper presents COPDFlowNet, a novel deep-learning framework that leverages a…
The field of numerical simulation is of significant importance for the design and management of real-world systems, with partial differential equations (PDEs) being a commonly used mathematical modeling tool. However, solving PDEs remains…
Accurate, automatic and complete extraction of pulmonary airway in medical images plays an important role in analyzing thoracic CT volumes such as lung cancer detection, chronic obstructive pulmonary disease (COPD), and…
Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…
The accurate prediction of aerothermal surface loading is of paramount importance for the design of high speed flight vehicles. In this work, we consider the numerical solution of hypersonic flow over a double-finned geometry,…
We introduce a closure model for wall-modeled large-eddy simulation (WMLES), referred to as the Building-block Flow Model (BFM). The foundation of the model rests on the premise that a finite collection of simple flows encapsulates the…
Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…
Ventilated cavities in the wake of a two-dimensional bluff body are studied experimentally via time-resolved X-ray densitometry. With a systematic variation of flow velocity and gas injection rate, expressed as Froude number ($Fr$) and…
Nasal breathing difficulties (NBD) are widespread and difficult to diagnose; the failure rate of their surgical corrections is high. Computational Fluid Dynamics (CFD) enables diagnosis of NBD and surgery planning, by comparing a…
Segmentation of lung tissue in computed tomography (CT) images is a precursor to most pulmonary image analysis applications. Semantic segmentation methods using deep learning have exhibited top-tier performance in recent years, however…
We develop a 3D aerothermodynamic simulator for the Orion reentry capsule at hypersonic speeds, a timely case study given its role in upcoming lunar missions. The large computational meshes required for these scenarios make traditional…
Urban wind flow modeling and simulation play an important role in air quality assessment and sustainable city planning. A key challenge for modeling and simulation is handling the complex geometries of the urban landscape. Low order models…
The Generation and propagation of the human voice is studied in two-dimensions using a full-body domain, using direct numerical simulation. The fluid/air in the vocal tract is modeled as a compressible and viscous fluid interacting with the…
Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…
The Pulmonary Function Test (PFT) is an widely utilized and rigorous classification test for lung function evaluation, serving as a comprehensive tool for lung diagnosis. Meanwhile, Electrical Impedance Tomography (EIT) is a rapidly…
Modelling flow and acoustics in a constricted duct at low Mach numbers is important for investigating many physiological phenomena such as phonation, generation of arterial murmurs, and pulmonary conditions involving airway obstruction. The…
Inspiratory and expiratory flow in a multi-generation pig lung airway was numerically studied at a peak tracheal flow rate corresponding to a Reynolds number of 1150. The model was validated by comparing velocity distributions with previous…