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We report a multiscale modeling study for charged cylindrical nanopores using three modeling levels that include (1) an all-atom explicit-water model studied with molecular dynamics (MD), and reduced models with implicit water containing…

Continuum models to handle solvent and electrolyte effects in an effective way have a long tradition in quantum-chemistry simulations and are nowadays also being introduced in computational condensed-matter and materials simulations. A key…

Liquid structure at solid-liquid interfaces is critical for many natural and engineered processes ranging from biological signal transduction to electrochemical energy conversion. Advanced experimental and computational methods have…

Understanding the contact between solid surfaces is a long standing problem which has a strong impact on the physics of many processes such as adhesion, friction, lubrication and wear. Experimentally, the investigation of solid/solid…

Materials Science · Physics 2019-02-25 F. Rieutord , C. Rauer , H. Moriceau

An analytical solution based on a diffuse interface model is presented for an isothermal evaporation problem under sub-saturation pressure. The macroscopic equations are derived from the free-energy method, widely recognized in the lattice…

The AGBNP2 implicit solvent model, an evolution of the Analytical Generalized Born plus Non-Polar (AGBNP) model we have previously reported, is presented with the aim of modeling hydration effects beyond those described by conventional…

Biomolecules · Quantitative Biology 2009-03-19 Emilio Gallicchio , Kristina Paris , Ronald M. Levy

We present an implementation in a linear-scaling density-functional theory code of an electronic enthalpy method, which has been found to be natural and efficient for the ab initio calculation of finite systems under hydrostatic pressure.…

Mesoscale and Nanoscale Physics · Physics 2015-06-16 Niccolò R. C. Corsini , Andrea Greco , Nicholas D. M. Hine , Carla Molteni , Peter D. Haynes

A statistical thermodynamic development is given of a new implicit solvent model that avoids the traditional system size limitations of computer simulation of macromolecular solutions with periodic boundary conditions. This implicit solvent…

Chemical Physics · Physics 2009-10-31 Lawrence R. Pratt , Susan B. Rempe

We investigate interfacial fluid dynamics and heat transfer at nanoscales using an improved diffuse interface approach for liquid-vapor interfaces in non-equilibrium. Conventional Navier-Stokes-Korteweg (NSK) formulations often fail to…

Fluid Dynamics · Physics 2026-03-11 Rahul Bhattacharjee , Henning Struchtrup , Anirudh Singh Rana

An energy-based liquid-vapor interface detection method is presented using molecular dynamics (MD) simulations of liquid menisci confined between two parallel plates under equilibrium and evaporation/condensation conditions. This method…

Chemical Physics · Physics 2021-09-02 Mustafa Ozsipahi , Yigit Akkus , Chinh Thanh Nguyen , Ali Beskok

Delivering the full benefits of first principles calculations to battery materials demands the development of accurate and computationally-efficient electronic structure methods that incorporate the effects of the electrolyte environment…

We develop a diffuse solid method that is versatile and accurate for modeling wetting and multiphase flows in highly complex geometries. In this scheme, we harness N + 1-component phase field models to investigate interface shapes and flow…

We propose a sharp-interface model for solid-state dewetting of thin films with wetting potential, where the wetting effect is incorporated through a thickness-dependent surface energy. The model is governed by surface diffusion together…

Numerical Analysis · Mathematics 2026-04-29 Weijie Huang , Xinran Ruan

The Polarizable Continuum Model (PCM) can be used in conjunction with Density Functional Theory (DFT) and its time-dependent extension (TDDFT) to simulate the electronic and optical properties of molecules and nanoparticles immersed in a…

Materials Science · Physics 2015-10-28 Alain Delgado , Stefano Corni , Stefano Pittalis , Carlo Andrea Rozzi

Accurate modeling of the solvent environment for biological molecules is crucial for computational biology and drug design. A popular approach to achieve long simulation time scales for large system sizes is to incorporate the effect of the…

Computational Physics · Physics 2021-08-27 Yaoyi Chen , Andreas Krämer , Nicholas E. Charron , Brooke E. Husic , Cecilia Clementi , Frank Noé

We propose a generalisation of molecular density functional theory to describe inhomogeneous solvent mixture, with the objective of modelling electrolytic solutions. Two electrolytic models are presented, both within the HNC approximation.…

Chemical Physics · Physics 2025-11-13 Guillaume Jeanmairet , Luc Belloni , Daniel Borgis

In a multiscale modeling approach, we present computer simulation results for a rectifying bipolar nanopore on two modeling levels. In an all-atom model, we use explicit water to simulate ion transport directly with the molecular dynamics…

Mesoscale and Nanoscale Physics · Physics 2018-03-13 Zoltán Ható , Mónika Valiskó , Tamás Kristóf , Dirk Gillespie , Dezső Boda

This work presents a novel surface decomposition method for the sensitivity analysis of first-passage dynamic reliability of linear systems subjected to Gaussian random excitations. The method decomposes the sensitivity of first-passage…

Methodology · Statistics 2026-03-09 Jianhua Xian , Sai Hung Cheung , Cheng Su

This article presents a multi-physics methodology for the numerical simulation of physical systems that involve the non-linear interaction of multi-phase reactive fluids and elastoplastic solids, inducing high strain-rates and high…

Computational Physics · Physics 2021-06-04 Tim Wallis , Philip T. Barton , Nikolaos Nikiforakis

We present a method to derive implicit solvent models of electrolyte solutions from all-atom descriptions; providing analytical expressions of the thermodynamic and structural properties of the ions consistent with the underlying explicit…

Chemical Physics · Physics 2010-01-18 J. J. Molina , J. -F. Dufreche , M. Salanne , O. Bernard , M. Jardat , P. Turq