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Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

Machine Learning · Computer Science 2016-12-06 Colin J Brown , Ghassan Hamarneh

Brain network analysis is vital for understanding the neural interactions regarding brain structures and functions, and identifying potential biomarkers for clinical phenotypes. However, widely used brain signals such as Blood Oxygen Level…

Machine Learning · Computer Science 2024-05-02 Kaiqiao Han , Yi Yang , Zijie Huang , Xuan Kan , Yang Yang , Ying Guo , Lifang He , Liang Zhan , Yizhou Sun , Wei Wang , Carl Yang

Network analysis is rapidly becoming a standard tool for studying functional magnetic resonance imaging (fMRI) data. In this framework, different brain areas are mapped to the nodes of a network, whose links depict functional dependencies…

Neurons and Cognition · Quantitative Biology 2017-05-30 Rainer Kujala , Enrico Glerean , Raj Kumar Pan , Iiro P. Jääskeläinen , Mikko Sams , Jari Saramäki

The functional independence measure (FIM) is widely used to evaluate patients' physical independence in activities of daily living. However, traditional FIM assessment imposes a significant burden on both patients and healthcare…

Machine Learning · Computer Science 2025-11-17 Jun Masaki , Ariaki Higashi , Naoko Shinagawa , Kazuhiko Hirata , Yuichi Kurita , Akira Furui

Functional MRI (fMRI) research, employing naturalistic stimuli like movies, explores brain network interactions in complex cognitive processes such as empathy. The empathy network encompasses multiple brain areas, including the Insula, PFC,…

Neurons and Cognition · Quantitative Biology 2024-03-13 Sasanka GRS , Ayushi Agrawal , Santosh Nannuru , Kavita Vemuri

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

We propose a method for estimating more reproducible functional networks that are more strongly associated with dynamic task activity by using recurrent neural networks with long short term memory (LSTMs). The LSTM model is trained in an…

Quantitative Methods · Quantitative Biology 2021-05-07 Nicha C. Dvornek , Pamela Ventola , James S. Duncan

Background: The brain's functional network constantly adapts to external changes. However, the mechanisms underlying this dynamic adaptive behavior in stroke patients with motor injuries and its role in post-stroke motor recovery remain…

Neurons and Cognition · Quantitative Biology 2024-01-18 Kaichao Wu , Beth Jelfs , Katrina Neville , Qiang Fang

Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However,…

Machine Learning · Computer Science 2026-03-11 Jingfeng Tang , Peng Cao , Guangqi Wen , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in…

Neurons and Cognition · Quantitative Biology 2019-07-03 Ahmed El Gazzar , Leonardo Cerliani , Guido van Wingen , Rajat Mani Thomas

We present an empirical evaluation of fMRI data augmentation via synthesis. For synthesis we use generative mod-els trained on real neuroimaging data to produce novel task-dependent functional brain images. Analyzed generative mod-els…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Peiye Zhuang , Alexander G. Schwing , Sanmi Koyejo

We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

Neurons and Cognition · Quantitative Biology 2013-02-18 Vesna Vuksanović , Philipp Hövel

Data produced by resting-state functional Magnetic Resonance Imaging are widely used to infer brain functional connectivity networks. Such networks correlate neural signals to connect brain regions, which consist in groups of dependent…

Methodology · Statistics 2023-12-05 Hanâ Lbath , Alexander Petersen , Sophie Achard

The MRI-derived brain network serves as a pivotal instrument in elucidating both the structural and functional aspects of the brain, encompassing the ramifications of diseases and developmental processes. However, prevailing methodologies,…

Machine Learning · Computer Science 2024-05-24 Haoteng Tang , Guodong Liu , Siyuan Dai , Kai Ye , Kun Zhao , Wenlu Wang , Carl Yang , Lifang He , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Functional brain network analysis has become an indispensable tool for brain disease analysis. It is profoundly impacted by deep learning methods, which can characterize complex connections between ROIs. However, the research on foundation…

Image and Video Processing · Electrical Eng. & Systems 2025-08-08 Yifei Tang , Hongjie Jiang , Changhong Jing , Hieu Pham , Shuqiang Wang

Functional magnetic resonance imaging (fMRI) is an emerging neuroimaging modality that is commonly modeled as networks of Regions of Interest (ROIs) and their connections, named functional connectivity, for understanding the brain functions…

Neurons and Cognition · Quantitative Biology 2024-10-01 Haokai Zhao , Haowei Lou , Lina Yao , Yu Zhang

fMRI is a unique non-invasive approach for understanding the functional organization of the human brain, and task-based fMRI promotes identification of functionally relevant brain regions associated with a given task. Here, we use fMRI…

Neurons and Cognition · Quantitative Biology 2019-02-06 A. Yamin , M. Dayan , L. Squarcina , P. Brambilla , V. Murino , V. Diwadkar , D. Sona

Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

Neurons and Cognition · Quantitative Biology 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

Joint multimodal functional data acquisition, where functional data from multiple modes are measured simultaneously from the same subject, has emerged as an exciting modern approach enabled by recent engineering breakthroughs in the…

Methodology · Statistics 2023-10-03 Katherine Tsai , Boxin Zhao , Sanmi Koyejo , Mladen Kolar