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It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…

Methodology · Statistics 2014-04-08 Xi Luo

Acquisition of bimanual motor skills, critical in several applications ranging from robotic teleoperations to surgery, is associated with a protracted learning curve. Brain connectivity based on functional Near Infrared Spectroscopy (fNIRS)…

Neurons and Cognition · Quantitative Biology 2020-01-03 F. Deligianni , H. Singh , H. N. Modi , S. Jahani , M. Yucel , A. Darzi , D. R. Leff , G. Z. Yang

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

Estimating brain effective connectivity (EC) from functional magnetic resonance imaging (fMRI) data can aid in comprehending the neural mechanisms underlying human behavior and cognition, providing a foundation for disease diagnosis.…

Machine Learning · Computer Science 2025-03-17 Wen Xiong , Jinduo Liu , Junzhong Ji , Fenglong Ma

Working memory plays a crucial role in various aspects of human life. Therefore, it has been an area of interest in different research studies, especially neuroscience. The neuroscientists investigating working memory have primarily…

Neurons and Cognition · Quantitative Biology 2024-11-26 Sepehr Gourabi , Masoud Lotfalipour , Reza Khosrowabadi , Reza Jafari

In neuroscience, researchers seek to uncover the connectivity of neurons from large-scale neural recordings or imaging; often people employ graphical model selection and estimation techniques for this purpose. But, existing technologies can…

Machine Learning · Statistics 2021-04-14 Minjie Wang , Genevera I. Allen

Mapping from functional connectivity (FC) to structural connectivity (SC) can facilitate multimodal brain network fusion and discover potential biomarkers for clinical implications. However, it is challenging to directly bridge the reliable…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Qiankun Zuo , Bangjun Lei , Wanyu Qiu , Changhong Jing , Jin Hong , Shuqiang Wang

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

Applications · Statistics 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

Computation · Statistics 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

Computation · Statistics 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

Applications · Statistics 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

Methodology · Statistics 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

Understanding how spontaneous brain activity relates to stimulus-driven neural responses is a fundamental challenge in cognitive neuroscience. While task-based functional magnetic resonance imaging (fMRI) captures localized stimulus-evoked…

Neurons and Cognition · Quantitative Biology 2025-09-18 Chuyang Zhou , Ziao Ji , Daochang Liu , Dongang Wang , Chenyu Wang , Chang Xu

Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

We investigate whether and how we can improve the cost efficiency of neuroimaging studies with well-tailored fMRI tasks. The comparative study is conducted using a novel network science-driven Bayesian connectome-based predictive method,…

Applications · Statistics 2024-11-05 Xinzhi Zhang , Leslie A Hulvershorn , Todd Constable , Yize Zhao , Selena Wang

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

Using deep learning models to recognize functional brain networks (FBNs) in functional magnetic resonance imaging (fMRI) has been attracting increasing interest recently. However, most existing work focuses on detecting static FBNs from…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Yiheng Liu , Enjie Ge , Mengshen He , Zhengliang Liu , Shijie Zhao , Xintao Hu , Dajiang Zhu , Tianming Liu , Bao Ge

Single-subject mapping of resting-state brain functional activity to non-imaging phenotypes is a major goal of neuroimaging. The large majority of learning approaches applied today rely either on static representations or on short-term…

Machine Learning · Computer Science 2022-08-09 Ahmed El-Gazzar , Rajat Mani Thomas , Guido Van Wingen