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Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Purpose: In diffusion MRI (dMRI), the volumetric and bundle analyses of whole-brain tissue microstructure and connectivity can be severely impeded by an incomplete field-of-view (FOV). This work aims to develop a method for imputing the…

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Uncertainty estimation aims to evaluate the confidence of a trained deep neural network. However, existing uncertainty estimation approaches rely on low-dimensional distributional assumptions and thus suffer from the high dimensionality of…

Machine Learning · Computer Science 2023-10-26 Tsai Hor Chan , Kin Wai Lau , Jiajun Shen , Guosheng Yin , Lequan Yu

Diffusion tensor imaging (DTI) is a novel modality of magnetic resonance imaging that allows noninvasive mapping of the brain's white matter. A particular map derived from DTI measurements is a map of water principal diffusion directions,…

Applications · Statistics 2008-12-18 Armin Schwartzman , Robert F. Dougherty , Jonathan E. Taylor

The space of probability densities is an infinite-dimensional Riemannian manifold, with Riemannian metrics in two flavors: Wasserstein and Fisher--Rao. The former is pivotal in optimal mass transport (OMT), whereas the latter occurs in…

Differential Geometry · Mathematics 2017-11-21 Klas Modin

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

Imaging modalities provide clinicians with real-time visualization of anatomical regions of interest (ROI) for the purpose of minimally invasive surgery. During the procedure, low-resolution image data are acquired and registered with…

Medical Physics · Physics 2020-11-10 Haolin Liu , Ye Han , Daniel Emerson , Houriyeh Majditehran , Qi Wang , Yoed Rabin , Levent Burak Kara

Effective learning of asymmetric and local features in images and other data observed on multi-dimensional grids is a challenging objective critical for a wide range of image processing applications involving biomedical and natural images.…

Methodology · Statistics 2022-10-06 Meng Li , Li Ma

One of the fundamental problems in machine learning is the estimation of a probability distribution from data. Many techniques have been proposed to study the structure of data, most often building around the assumption that observations…

Machine Learning · Statistics 2013-02-22 Oren Rippel , Ryan Prescott Adams

Refractive error, one of the leading cause of visual impairment, can be corrected by simple interventions like prescribing eyeglasses. We trained a deep learning algorithm to predict refractive error from the fundus photographs from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Avinash V. Varadarajan , Ryan Poplin , Katy Blumer , Christof Angermueller , Joe Ledsam , Reena Chopra , Pearse A. Keane , Greg S. Corrado , Lily Peng , Dale R. Webster

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Machine Learning · Computer Science 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

This work explores the ability of computer vision algorithms to characterise dark matter haloes formed in different models of structure formation. We produce surface mass density maps of the most massive haloes in a suite of eight numerical…

Cosmology and Nongalactic Astrophysics · Physics 2017-04-19 Julian Merten , Quim Llorens , Hans Winther

Deep generative models have gained recent traction in accelerated MRI reconstruction. Diffusion priors are particularly promising given their representational fidelity. Instead of the target transformation from undersampled to fully-sampled…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Muhammad U. Mirza , Onat Dalmaz , Hasan A. Bedel , Gokberk Elmas , Yilmaz Korkmaz , Alper Gungor , Salman UH Dar , Tolga Çukur

Designing generative models for 3D structural brain MRI that synthesize morphologically-plausible and attribute-specific (e.g., age, sex, disease state) samples is an active area of research. Existing approaches based on frameworks like…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Alan Q. Wang , Fangrui Huang , Bailey Trang , Wei Peng , Mohammad Abbasi , Kilian Pohl , Mert Sabuncu , Ehsan Adeli

Computed tomography (CT) reconstructs volumetric images using X-ray projection data acquired from multiple angles around an object. For low-dose or sparse-view CT scans, the classic image reconstruction algorithms often produce severe noise…

Medical Physics · Physics 2024-03-04 Wenxiang Cong , Wenjun Xia , Ge Wang

Diffusion tensor imaging (DTI) is a prevalent neuroimaging tool in analyzing the anatomical structure. The distinguishing feature of DTI is that the voxel-wise variable is a 3x3 positive definite matrix other than a scalar, describing the…

Methodology · Statistics 2021-03-30 Zhou Lan

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Automated fetal brain extraction from full-uterus MRI is a challenging task due to variable head sizes, orientations, complex anatomy, and prevalent artifacts. While deep-learning (DL) models trained on synthetic images have been successful…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Javid Dadashkarimi , Valeria Pena Trujillo , Camilo Jaimes , Lilla Zöllei , Malte Hoffmann