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Related papers: Phase field model of cell motility: sharp interfac…

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We consider a system of two coupled parabolic PDEs introduced in [1] to model motility of eukaryotic cells. We study the asymptotic behavior of solutions in the limit of a small parameter related to the width of the interface in phase field…

Analysis of PDEs · Mathematics 2016-02-05 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

This letter is concerned with asymptotic analysis of a PDE model for motility of a eukaryotic cell on a substrate. This model was introduced in [1], where it was shown numerically that it successfully reproduces experimentally observed…

Analysis of PDEs · Mathematics 2016-04-12 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

We consider sharp interface asymptotics for a phase field model of two phase near spherical biomembranes involving a coupling between the local mean curvature and the local composition proposed by the first and second authors. The model is…

Analysis of PDEs · Mathematics 2020-12-24 Charles M. Elliott , Luke Hatcher , Björn Stinner

This paper deals with the evolution equation of a curve obtained as the sharp interface limit of a non-linear system of two reaction-diffusion PDEs. This system was introduced as a phase-field model of (crawling) motion of eukaryotic cells…

Analysis of PDEs · Mathematics 2016-03-23 Matthew S. Mizuhara , Leonid Berlyand , Volodymyr Rybalko , Lei Zhang

The use of continuum phase-field models to describe the motion of well-defined interfaces is discussed for a class of phenomena, that includes order/disorder transitions, spinodal decomposition and Ostwald ripening, dendritic growth, and…

Soft Condensed Matter · Physics 2009-10-31 K. R. Elder , Martin Grant , Nikolas Provatas , J. M. Kosterlitz

In this paper, we consider the sharp interface limit of a matrix-valued Allen-Cahn equation, which takes the form: $$\partial_t A=\Delta A-\varepsilon^{-2}( A A^{\mathrm{T}}A-…

Analysis of PDEs · Mathematics 2021-06-16 Mingwen Fei , Fanghua Lin , Wei Wang , Zhifei Zhang

Phase-field models have recently had great success in describing the dynamic morphologies and motility of eukaryotic cells. In this work we investigate the minimal phase-field model introduced in [Berlyand, Potomkin, Rybalko (2017)].…

Cell Behavior · Quantitative Biology 2020-08-03 Nicolas Bolle , Matthew S. Mizuhara

We investigate the sharp interface limit of a diffuse interface system that couples the Allen--Cahn equation with the instationary Navier--Stokes system in a bounded domain in $\mathbb{R}^d$ with $d \in \{2,3\}$. This model is used to…

Analysis of PDEs · Mathematics 2022-05-17 Sebastian Hensel , Yuning Liu

We consider the sharp interface limit for the scalar-valued and vector-valued Allen-Cahn equation with homogeneous Neumann boundary condition in a bounded smooth domain $\Omega$ of arbitrary dimension $N\geq 2$ in the situation when a…

Analysis of PDEs · Mathematics 2021-05-18 Maximilian Moser

The interface dynamics of a 3D cell immersed in a 3D extracellular matrix is investigated. We suggest a 3D generalization of a known 2D minimal phase field model suggested in [1] for the description of keratocyte motility. Our model…

Biological Physics · Physics 2021-06-04 Mohammad Abu Hamed , Alexander A. Nepomnyashchy

We construct gradient structures for free boundary problems with nonlinear elasticity and study the impact of moving contact lines. In this context, we numerically analyze how phase-field models converge to certain sharp-interface limits…

Analysis of PDEs · Mathematics 2024-06-26 Leonie Schmeller , Dirk Peschka

In this letter, we derive the sharp-interface limit of the Cahn-Hilliard-Biot equations using formal matched asymptotic expansions. We find that in each sub-domain, the quasi-static Biot equations are obtained with domain-specific material…

Analysis of PDEs · Mathematics 2024-12-06 Erlend Storvik , Carina Bringedal

We analyze the sharp interface limit for the Allen-Cahn equation with an anisotropic, spatially periodic mobility coefficient and prove that the large-scale behavior of interfaces is determined by mean curvature flow with an effective…

Analysis of PDEs · Mathematics 2020-12-01 Peter S. Morfe

We perform an analytical investigation of the cell interface dynamics in the framework of a minimal phase field model of cell motility suggested in [1], which consists of two coupled evolution equations for the order parameter and a…

Biological Physics · Physics 2019-10-04 Mohammad Abu Hamed , Alexander A. Nepomnyashchy

We consider the Allen-Cahn equation with nonlinear anisotropic diffusion and derive anisotropic direction-dependent curvature flow under the sharp interface limit. The anisotropic curvature flow was already studied, but its derivation is…

Analysis of PDEs · Mathematics 2024-03-05 Tadahisa Funaki , Hyunjoon Park

We study a non-linear and non-local evolution equation for curves obtained as the sharp interface limit of a phase-field model for crawling motion of eukaryotic cells on a substrate. We establish uniqueness of solutions to the sharp…

Analysis of PDEs · Mathematics 2017-03-03 Matthew S. Mizuhara , Peng Zhang

We analyze a two-dimensional phase field model designed to describe the dynamics of crystalline grains. The phenomenological free energy is a functional of two order parameters. The first one reflects the orientational order while the…

Materials Science · Physics 2009-10-31 Alexander E. Lobkovsky , James A. Warren

We consider the sharp interface limit of the Allen-Cahn equation with homogeneous Neumann boundary condition in a two-dimensional domain $\Omega$, in the situation where an interface has developed and intersects $\partial\Omega$. Here a…

Analysis of PDEs · Mathematics 2018-06-07 Helmut Abels , Maximilian Moser

We consider the sharp interface limit of a coupled Stokes/Allen-Cahn system, when a parameter $\varepsilon>0$ that is proportional to the thickness of the diffuse interface tends to zero, in a two dimensional bounded domain. For…

Analysis of PDEs · Mathematics 2017-01-04 Helmut Abels , YuNing Liu

In this work, the sharp interface limit of the degenerate Cahn-Hilliard equation (in two space dimensions) with a polynomial double well free energy and a quadratic mobility is derived via a matched asymptotic analysis involving…

Mathematical Physics · Physics 2015-07-10 Alpha Albert Lee , Andreas Münch , Endre Süli
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