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Machine learning methods are used to discover complex nonlinear relationships in biological and medical data. However, sophisticated learning models are computationally unfeasible for data with millions of features. Here we introduce the…

Multiple imputation (MI) has been widely applied to missing value problems in biomedical, social and econometric research, in order to avoid improper inference in the downstream data analysis. In the presence of high-dimensional data,…

Methodology · Statistics 2023-05-04 Zhiqi Bu , Zongyu Dai , Yiliang Zhang , Qi Long

Recently, considerable interest has focused on variable selection methods in regression situations where the number of predictors, $p$, is large relative to the number of observations, $n$. Two commonly applied variable selection approaches…

Applications · Statistics 2011-04-19 Peter Radchenko , Gareth M. James

We propose a fast bivariate smoothing approach for symmetric surfaces that has a wide range of applications. We show how it can be applied to estimate the covariance function in longitudinal data as well as multiple additive covariances in…

Computation · Statistics 2016-09-23 Jona Cederbaum , Fabian Scheipl , Sonja Greven

Nonlinear relationships between covariates and a response variable of interest are frequently encountered in animal science research. Within statistical models, these nonlinear effects have, traditionally, been handled using a range of…

Applications · Statistics 2025-10-28 Gavin L. Simpson

This paper investigates the two-step estimation of a high dimensional additive regression model, in which the number of nonparametric additive components is potentially larger than the sample size but the number of significant additive…

Statistics Theory · Mathematics 2013-01-30 Kengo Kato

Multiple-group data is widely used in genomic studies, finance, and social science. This study investigates a block structure that consists of covariate and response groups. It examines the block-selection problem of high-dimensional models…

Methodology · Statistics 2024-12-30 Weixiong Liang , Yuehan Yang

Semi-supervised multi-label feature selection has recently been developed to solve the curse of dimensionality problem in high-dimensional multi-label data with certain samples missing labels. Although many efforts have been made, most…

Machine Learning · Computer Science 2025-10-10 Li Yang , Yanyong Huang , Dongjie Wang , Ke Li , Xiuwen Yi , Fengmao Lv , Tianrui Li

We consider a high-dimensional multi-outcome regression in which $q,$ possibly dependent, binary and continuous outcomes are regressed onto $p$ covariates. We model the observed outcome vector as a partially observed latent realization from…

Methodology · Statistics 2025-11-05 Soham Ghosh , Sameer K. Deshpande

Penalized B-splines are routinely used in additive models to describe smooth changes in a response with quantitative covariates. It is typically done through the conditional mean in the exponential family using generalized additive models…

Methodology · Statistics 2020-05-12 Philippe Lambert

The pattern of zero entries in the inverse covariance matrix of a multivariate normal distribution corresponds to conditional independence restrictions between variables. Covariance selection aims at estimating those structural zeros from…

Statistics Theory · Mathematics 2016-08-16 Nicolai Meinshausen , Peter Bühlmann

In many statistical modeling problems, such as classification and regression, it is common to encounter sparse and blocky coefficients. Sparse fused Lasso is specifically designed to recover these sparse and blocky structured features,…

Statistics Theory · Mathematics 2024-05-30 Xiaofei Wu , Rongmei Liang , Zhimin Zhang , Zhenyu Cui

Additive nonparametric regression models provide an attractive tool for variable selection in high dimensions when the relationship between the response and predictors is complex. They offer greater flexibility compared to parametric…

Machine Learning · Statistics 2016-07-12 Garret Vo , Debdeep Pati

In partially linear additive models the response variable is modelled with a linear component on a subset of covariates and an additive component in which the rest of the covariates enter to the model as a sum of univariate unknown…

Methodology · Statistics 2025-02-19 Alejandra Mercedes Martínez

We propose a method for adaptive nonlinear sequential modeling of vector-time series data. Data is modeled as a nonlinear function of past values corrupted by noise, and the underlying non-linear function is assumed to be approximately…

Methodology · Statistics 2017-10-11 Qiuyi Han , Jie Ding , Edoardo Airoldi , Vahid Tarokh

Methods for choosing a fixed set of knot locations in additive spline models are fairly well established in the statistical literature. While most of these methods are in principle directly extendable to non-additive surface models, they…

Computation · Statistics 2018-07-03 Feng Li , Mattias Villani

Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional…

Statistics Theory · Mathematics 2018-10-05 Francis K. C. Hui , Chong You , Han Lin Shang , Samuel Müller

We consider a high-dimensional regression model with a possible change-point due to a covariate threshold and develop the Lasso estimator of regression coefficients as well as the threshold parameter. Our Lasso estimator not only selects…

Statistics Theory · Mathematics 2019-08-23 Sokbae Lee , Myung Hwan Seo , Youngki Shin

The paper considers variable selection in linear regression models where the number of covariates is possibly much larger than the number of observations. High dimensionality of the data brings in many complications, such as (possibly…

Methodology · Statistics 2016-11-29 Haeran Cho , Piotr Fryzlewicz

We present a new class of methods for high-dimensional nonparametric regression and classification called sparse additive models (SpAM). Our methods combine ideas from sparse linear modeling and additive nonparametric regression. We derive…

Statistics Theory · Mathematics 2008-04-09 Pradeep Ravikumar , John Lafferty , Han Liu , Larry Wasserman
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