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Prompt optimization has become crucial for enhancing the performance of large language models (LLMs) across a broad range of tasks. Although many research papers demonstrate its effectiveness, practical adoption is hindered because existing…

Computation and Language · Computer Science 2026-02-24 Tom Zehle , Timo Heiß , Moritz Schlager , Matthias Aßenmacher , Matthias Feurer

The availability of open-source molecular simulation software packages allows scientists and engineers to focus on running and analyzing simulations without having to write, parallelize, and validate their own simulation software. While…

Computational Physics · Physics 2025-10-03 Simon Gravelle , Cecilia M. S. Alvares , Jacob R. Gissinger , Axel Kohlmeyer

MLMOD is a software package for incorporating machine learning approaches and models into simulations of microscale mechanics and molecular dynamics in LAMMPS. Recent machine learning approaches provide promising data-driven approaches for…

Machine Learning · Computer Science 2023-10-24 Paul J. Atzberger

We present version 3 of the open-source simulator for flow and transport processes in porous media DuMu$^\text{x}$. DuMu$^\text{x}$ is based on the modular C++ framework Dune (Distributed and Unified Numerics Environment) and is developed…

Large Language Models (LLMs) have achieved remarkable performance across various reasoning tasks, yet post-training is constrained by inefficient sample utilization and inflexible difficulty samples processing. To address these limitations,…

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

Recent progress in artificial intelligence (AI) and high-performance computing (HPC) have brought potentially game-changing opportunities in accelerating reactive flow simulations. In this study, we introduce an open-source computational…

Computational Engineering, Finance, and Science · Computer Science 2023-12-22 Runze Mao , Yingrui Wang , Min Zhang , Han Li , Jiayang Xu , Xinyu Dong , Yan Zhang , Zhi X. Chen

DeePMD-kit is a powerful open-source software package that facilitates molecular dynamics simulations using machine learning potentials (MLP) known as Deep Potential (DP) models. This package, which was released in 2017, has been widely…

Machine learning plays an important and growing role in molecular simulation. The newest version of the OpenMM molecular dynamics toolkit introduces new features to support the use of machine learning potentials. Arbitrary PyTorch models…

Since the release of T\"ULU [Wang et al., 2023b], open resources for instruction tuning have developed quickly, from better base models to new finetuning techniques. We test and incorporate a number of these advances into T\"ULU, resulting…

Enhanced sampling algorithms have emerged as powerful methods to extend the utility of molecular dynamics simulations and allow the sampling of larger portions of the configuration space of complex systems in a given amount of simulation…

Statistical Mechanics · Physics 2022-12-19 Jérôme Hénin , Tony Lelièvre , Michael R. Shirts , Omar Valsson , Lucie Delemotte

CPL here stands for a computer programming language conceived and developed by the author since 1993, but published for the first time in 2020. It was born as a Compiled Programming Language, designed together with its compiler and…

Programming Languages · Computer Science 2021-11-19 Paolo Luchini

Machine learning (ML) provides a broad spectrum of tools and architectures that enable the transformation of data from simulations and experiments into useful and explainable science, thereby augmenting domain knowledge. Furthermore,…

Plasma Physics · Physics 2024-09-05 Farbod Faraji , Maryam Reza

This report provides an introduction to the ensmallen numerical optimization library, as well as a deep dive into the technical details of how it works. The library provides a fast and flexible C++ framework for mathematical optimization of…

Mathematical Software · Computer Science 2023-11-16 Ryan R. Curtin , Marcus Edel , Rahul Ganesh Prabhu , Suryoday Basak , Zhihao Lou , Conrad Sanderson

The immersed boundary method (IB) is an elegant way to fully couple the motion of a fluid and deformations of an immersed elastic structure. In that vein, the IB2d software allows for expedited explorations of fluid-structure interaction…

Fluid Dynamics · Physics 2018-09-19 Nicholas Battista , Christopher Strickland , Aaron Barrett , Laura Miller

With the decline of Moore's law, optimizing program performance has become a major focus of software research. However, high-level optimizations such as API and algorithm changes remain elusive due to the difficulty of understanding the…

Combinatorial evolution - the creation of new things through the combination of existing things - can be a powerful way to evolve rather than design technical objects such as electronic circuits. Intriguingly, this seems to be an ongoing…

Software Engineering · Computer Science 2021-11-23 Sebastian Fix , Thomas Probst , Oliver Ruggli , Thomas Hanne , Patrik Christen

Microfluidic devices have been the subject of considerable attention in recent years. The development of novel microfluidic devices, their evaluation, and their validation requires simulations. While common methods based on Computational…

Fluid Dynamics · Physics 2024-11-05 Maria Emmerich , Florina Costamoling , Robert Wille

We present Liquid, an auto-regressive generation paradigm that seamlessly integrates visual comprehension and generation by tokenizing images into discrete codes and learning these code embeddings alongside text tokens within a shared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Junfeng Wu , Yi Jiang , Chuofan Ma , Yuliang Liu , Hengshuang Zhao , Zehuan Yuan , Song Bai , Xiang Bai

We present MIST, the Molecular Integration Simulation Toolkit, a lightweight and efficient software library written in C++ which provides an abstract in- terface to common molecular dynamics codes, enabling rapid and portable development of…