English
Related papers

Related papers: Scalable Protein Sequence Similarity Search using …

200 papers

The exponential growth of DNA sequencing data has outpaced traditional heuristic-based methods, which struggle to scale effectively. Efficient computational approaches are urgently needed to support large-scale similarity search, a…

Protein retrieval, which targets the deconstruction of the relationship between sequences, structures and functions, empowers the advancing of biology. Basic Local Alignment Search Tool (BLAST), a sequence-similarity-based algorithm, has…

Information Retrieval · Computer Science 2025-01-06 Yuxuan Wu , Xiao Yi , Yang Tan , Huiqun Yu , Guisheng Fan , Gaowei Zheng

Similarity search is critical for many database applications, including the increasingly popular online services for Content-Based Multimedia Retrieval (CBMR). These services, which include image search engines, must handle an overwhelming…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-10-16 Thiago S. F. X. Teixeira , George Teodoro , Eduardo Valle , Joel H. Saltz

Searching for local sequence patterns is one of the basic tasks in bioinformatics. Sequence patterns might have structural, functional or some other relevance, and numerous methods have been developed to detect and analyze them. These…

Quantitative Methods · Quantitative Biology 2018-08-01 Braslav Rabar , Strahil Ristov , Maja Zagorščak , Martin Rosenzweig , Pavle Goldstein

The Basic Local Alignment Search Tool (BLAST) is currently the most popular method for searching databases of biological sequences. BLAST compares sequences via similarity defined by a weighted edit distance, which results in it being…

Biomolecules · Quantitative Biology 2020-10-29 Amir Shanehsazzadeh , David Belanger , David Dohan

Identifying similar protein sequences is a core step in many computational biology pipelines such as detection of homologous protein sequences, generation of similarity protein graphs for downstream analysis, functional annotation and gene…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-01 Oguz Selvitopi , Saliya Ekanayake , Giulia Guidi , Georgios Pavlopoulos , Ariful Azad , Aydin Buluc

We present SLASH (Sketched LocAlity Sensitive Hashing), an MPI (Message Passing Interface) based distributed system for approximate similarity search over terabyte scale datasets. SLASH provides a multi-node implementation of the popular…

Databases · Computer Science 2020-08-19 Nicholas Meisburger , Anshumali Shrivastava

Finding similar data in high-dimensional spaces is one of the important tasks in multimedia applications. Approaches introduced to find exact searching techniques often use tree-based index structures which are known to suffer from the…

Databases · Computer Science 2022-11-17 Omid Jafari , Parth Nagarkar

Distributed tracing serves as a fundamental element in the monitoring of cloud-based and datacenter systems. It provides visibility into the full lifecycle of a request or operation across multiple services, which is essential for…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-12 Zhuangbin Chen , Zhihan Jiang , Yuxin Su , Michael R. Lyu , Zibin Zheng

We present ElasticHash, a novel approach for high-quality, efficient, and large-scale semantic image similarity search. It is based on a deep hashing model to learn hash codes for fine-grained image similarity search in natural images and a…

Computer Vision and Pattern Recognition · Computer Science 2023-05-10 Nikolaus Korfhage , Markus Mühling , Bernd Freisleben

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is…

Quantitative Methods · Quantitative Biology 2015-05-27 Kévin Vervier , Pierre Mahé , Maud Tournoud , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Single Molecule Real-Time (SMRT) sequencing is a recent advancement of Next Gen technology developed by Pacific Bio (PacBio). It comes with an explosion of long and noisy reads demanding cutting edge research to get most out of it. To deal…

Genomics · Quantitative Biology 2019-03-13 Angana Chakraborty , Sanghamitra Bandyopadhyay

MetaScope is a fast and accurate tool for analyzing (host-associated) metagenome datasets. Sequence alignment of reads against the host genome (if requested) and against microbial Genbank is performed using a new DNA aligner called SASS.…

Genomics · Quantitative Biology 2015-11-30 Benjamin Buchfink , Daniel H. Huson , Chao Xie

All pairs similarity search is a problem where a set of data objects is given and the task is to find all pairs of objects that have similarity above a certain threshold for a given similarity measure-of-interest. When the number of points…

Information Retrieval · Computer Science 2016-06-29 Aniket Chakrabarti , Srinivasan Parthasarathy

Recently, community has paid increasing attention on model scaling and contributed to developing a model family with a wide spectrum of scales. Current methods either simply resort to a one-shot NAS manner to construct a non-structural and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-18 Jiyang Xie , Xiu Su , Shan You , Zhanyu Ma , Fei Wang , Chen Qian

Protein motifs are conserved fragments occurred frequently in protein sequences. They have significant functions, such as active site of an enzyme. Search and clustering protein sequence motifs are computational intensive. Most existing…

Genomics · Quantitative Biology 2017-01-03 Haifeng Chen , Ting Chen

Data similarity (or distance) computation is a fundamental research topic which fosters a variety of similarity-based machine learning and data mining applications. In big data analytics, it is impractical to compute the exact similarity of…

Data Structures and Algorithms · Computer Science 2025-03-12 Wei Wu , Bin Li

Scalar field comparison is a fundamental task in scientific visualization. In topological data analysis, we compare topological descriptors of scalar fields -- such as persistence diagrams and merge trees -- because they provide succinct…

Computational Geometry · Computer Science 2024-09-18 Weiran Lyu , Raghavendra Sridharamurthy , Jeff M. Phillips , Bei Wang

Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

Scientists increasingly rely on Python tools to perform scalable distributed memory array operations using rich, NumPy-like expressions. However, many of these tools rely on dynamic schedulers optimized for abstract task graphs, which often…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-14 Melih Elibol , Vinamra Benara , Samyu Yagati , Lianmin Zheng , Alvin Cheung , Michael I. Jordan , Ion Stoica
‹ Prev 1 2 3 10 Next ›