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New biological assays like Perturb-seq link highly parallel CRISPR interventions to a high-dimensional transcriptomic readout, providing insight into gene regulatory networks. Causal gene regulatory networks can be represented by directed…

Machine Learning · Statistics 2024-02-22 Albert Xue , Jingyou Rao , Sriram Sankararaman , Harold Pimentel

There has been a growing interest in causal learning in recent years. Commonly used representations of causal structures, including Bayesian networks and structural equation models (SEM), take the form of directed acyclic graphs (DAGs). We…

Machine Learning · Computer Science 2025-11-20 Pavel Rytir , Ales Wodecki , Jakub Marecek

We propose a novel score-based approach to learning a directed acyclic graph (DAG) from observational data. We adapt a recently proposed continuous constrained optimization formulation to allow for nonlinear relationships between variables…

Machine Learning · Computer Science 2020-02-19 Sébastien Lachapelle , Philippe Brouillard , Tristan Deleu , Simon Lacoste-Julien

Faithfulness is the foundation of probability distribution and graph in causal discovery and causal inference. In this paper, several unfaithful probability distribution examples are constructed in three--vertices binary causality directed…

Machine Learning · Statistics 2025-01-31 Jingwei Liu

An important task in data analysis is the discovery of causal relationships between observed variables. For continuous-valued data, linear acyclic causal models are commonly used to model the data-generating process, and the inference of…

A directed acyclic graph (DAG) provides valuable prior knowledge that is often discarded in regression tasks in machine learning. We show that the independences arising from the presence of collider structures in DAGs provide meaningful…

Machine Learning · Statistics 2023-06-22 Shahine Bouabid , Jake Fawkes , Dino Sejdinovic

This paper considers the problem of estimating the structure of multiple related directed acyclic graph (DAG) models. Building on recent developments in exact estimation of DAGs using integer linear programming (ILP), we present an ILP…

Machine Learning · Statistics 2014-11-13 Chris J. Oates , Jim Q. Smith , Sach Mukherjee , James Cussens

This work addresses the problem of learning directed acyclic graphs (DAGs) from nodal observations generated by a linear structural equation model. DAG learning is a central task in signal processing, machine learning, and causal inference,…

Machine Learning · Computer Science 2026-05-20 Samuel Rey , Madeline navarro , Gonzalo Mateos

We consider graphs that represent pairwise marginal independencies amongst a set of variables (for instance, the zero entries of a covariance matrix for normal data). We characterize the directed acyclic graphs (DAGs) that faithfully…

Artificial Intelligence · Computer Science 2015-08-04 Johannes Textor , Alexander Idelberger , Maciej Liśkiewicz

Recovering the underlying Directed Acyclic Graph (DAG) structures from observational data presents a formidable challenge, partly due to the combinatorial nature of the DAG-constrained optimization problem. Recently, researchers have…

Machine Learning · Computer Science 2025-03-26 Zhen Zhang , Ignavier Ng , Dong Gong , Yuhang Liu , Mingming Gong , Biwei Huang , Kun Zhang , Anton van den Hengel , Javen Qinfeng Shi

Estimating causal models from observational data is a crucial task in data analysis. For continuous-valued data, Shimizu et al. have proposed a linear acyclic non-Gaussian model to understand the data generating process, and have shown that…

Machine Learning · Computer Science 2018-02-19 Chao Li , Shohei Shimizu

Conventional methods for causal structure learning from data face significant challenges due to combinatorial search space. Recently, the problem has been formulated into a continuous optimization framework with an acyclicity constraint to…

Machine Learning · Computer Science 2022-06-06 Hristo Petkov , Colin Hanley , Feng Dong

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

In public opinion studies, the relationships between opinions on different topics are likely to shift based on the characteristics of the respondents. Thus, understanding the complexities of public opinion requires methods that can account…

We introduce a novel class of labeled directed acyclic graph (LDAG) models for finite sets of discrete variables. LDAGs generalize earlier proposals for allowing local structures in the conditional probability distribution of a node, such…

Machine Learning · Statistics 2014-11-12 Johan Pensar , Henrik Nyman , Timo Koski , Jukka Corander

A key step in the Bayesian workflow for model building is the graphical assessment of model predictions, whether these are drawn from the prior or posterior predictive distribution. The goal of these assessments is to identify whether the…

Methodology · Statistics 2025-03-04 Teemu Säilynoja , Andrew R. Johnson , Osvaldo A. Martin , Aki Vehtari

Acyclic digraphs are the underlying representation of Bayesian networks, a widely used class of probabilistic graphical models. Learning the underlying graph from data is a way of gaining insights about the structural properties of a…

Machine Learning · Statistics 2022-05-06 Jack Kuipers , Giusi Moffa

The investigation of directed acyclic graphs (DAGs) encoding the same Markov property, that is the same conditional independence relations of multivariate observational distributions, has a long tradition; many algorithms exist for model…

Methodology · Statistics 2012-09-27 Alain Hauser , Peter Bühlmann

We propose causal preference elicitation, a Bayesian framework for expert-in-the-loop causal discovery that actively queries local edge relations to concentrate a posterior over directed acyclic graphs (DAGs). From any black-box…

Machine Learning · Computer Science 2026-02-03 Edwin V. Bonilla , He Zhao , Daniel M. Steinberg

Bayesian networks are widely used to learn and reason about the dependence structure of discrete variables. However, they are only capable of formally encoding symmetric conditional independence, which in practice is often too strict to…

Artificial Intelligence · Computer Science 2023-01-03 Manuele Leonelli , Gherardo Varando