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While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

We study the quantization of the M-theory G-flux on elliptically fibered Calabi-Yau fourfolds with singularities giving rise to unitary and symplectic gauge groups. We seek and find its relation to the Freed-Witten quantization of…

High Energy Physics - Theory · Physics 2015-06-04 Andres Collinucci , Raffaele Savelli

Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…

Biological Physics · Physics 2021-01-22 Youyuan Deng , Herbert Levine , Xiaoming Mao , Leonard M. Sander

This article is an invitation. It is, first, an invitation to consider as a subject worthy of attention the wide range of situations where small discrete elements, either bubbles, droplets or solid particles, are embedded in turbulent…

Fluid Dynamics · Physics 2023-11-06 Jean-Pierre Minier , Christophe Henry

Organisms often swim through fluids that are spatially inhomogeneous. If the fluids are polymeric, gradients in polymer concentration may lead to gradients in both fluid viscosity and elasticity. In this letter, we present theoretical…

Fluid Dynamics · Physics 2024-11-08 Vaseem A. Shaik , Jiahao Gong , Gwynn J. Elfring

A mode-coupling theory for the slow single-particle dynamics in fluids adsorbed in disordered porous media is derived, which complements previous work on the collective dynamics [V. Krakoviack, Phys. Rev. E 75, 031503 (2007)]. Its…

Disordered Systems and Neural Networks · Physics 2009-06-10 V. Krakoviack

Dehydration and brain interstitial fluid alterations associate to cognitive dysfunction. We now explore whether changes in matrix hydration are a possible common signal for modulation of water-transfer rates and neuron function.

Tissues and Organs · Quantitative Biology 2020-04-30 Maria P McGee , Michael Morykwas , Mary Kerns , Anirudh Vashisht , Ashok N Hegde , Louis Argenta

Microorganisms, such as bacteria and microalgae, often live in habitats consisting of a liquid phase and a plethora of interfaces. The precise ways in which these motile microbes behave in their confined environment remain unclear. Using…

Protein-DNA complexes with loops play a fundamental role in a wide variety of cellular processes, ranging from the regulation of DNA transcription to telomere maintenance. As ubiquitous as they are, their precise in vivo properties and…

Biomolecules · Quantitative Biology 2007-05-23 Leonor Saiz , Jose M. G. Vilar

Quantum molecular dynamics is applied to study the ground state properties of nuclear matter at subsaturation densities. Clustering effects are observed as to soften the equation of state at these densities. The structure of nuclear matter…

We study the role of active coupling on the transport properties of homogeneously charged macromolecules in an infinitely dilute solution. An enzyme becomes actively bound to a segment of the macromolecule, exerting an electrostatic force…

Soft Condensed Matter · Physics 2024-05-24 Tapas Singha , Siao-Fong Li , Murugappan Muthukumar

Geometric deep learning (GDL), which is based on neural network architectures that incorporate and process symmetry information, has emerged as a recent paradigm in artificial intelligence. GDL bears particular promise in molecular modeling…

Chemical Physics · Physics 2022-01-03 Kenneth Atz , Francesca Grisoni , Gisbert Schneider

Fluid membranes made out of lipid bilayers are the fundamental separation structure in eukaryotic cells. Many physiological processes rely on dramatic shape and topological changes (e.g. fusion, fission) of fluid membrane systems. Fluidity…

Numerical Analysis · Mathematics 2010-07-29 Marino Arroyo , Antonio DeSimone , Luca Heltai

Biological membranes are shaped by various proteins that either generate inward or outward membrane curvature. In this article, we investigate the membrane morphologies induced by mixtures of arc-shaped particles with coarse-grained…

Subcellular Processes · Quantitative Biology 2020-04-03 Francesco Bonazzi , Carol K. Hall , Thomas R. Weikl

We present a new modeling approach for G protein coupled receptors signaling systems, that take into account the compartmentalization of receptors and their effectors, both at plasma membrane and in dynamic intra-cellular vesicles called…

Analysis of PDEs · Mathematics 2023-05-23 Claire Alamichel , Juan Calvo , Erwan Hingant , Saoussen Latrach , Nathan Quiblier , Romain Yvinec

It is shown that new data from the HERMES collaboration, as well as all of the earlier improved data from experiments concerning the EMC effect and shadowing in deep-inelastic scattering of leptons from nuclei, provide strong evidence for…

High Energy Physics - Phenomenology · Physics 2011-07-19 Saul Barshay , Georg Kreyerhoff

Cellular uptake of nanoplastics is instrumental in their environmental accumulation and transfer to humans through the food chain. Despite extensive studies using spherical plastic nanoparticles, the influence of the morphological…

Soft Condensed Matter · Physics 2023-08-29 Xin Yong , Ke Du

We investigate the hydrodynamic effects on the dynamics of critical concentration fluctuations in multicomponent fluid membranes. Two geometrical cases are considered; (i) confined membrane case and (ii) supported membrane case. We…

Soft Condensed Matter · Physics 2010-11-29 Sanoop Ramachandran , Shigeyuki Komura , Kazuhiko Seki , Masayuki Imai

This is an investigation of the role of shuffling and concatenating in the theory of graph drawing. A simple syntactic description of these and related operations is proved complete in the context of finite partial orders, as general as…

Logic · Mathematics 2012-11-01 K. Dosen , Z. Petric

Many transport processes in nature take place on substrates, often considered as unidimensional lanes. These unidimensional substrates are typically non-static: affected by a fluctuating environment, they can undergo conformational changes.…

Statistical Mechanics · Physics 2013-01-11 Francesco Turci , Andrea Parmeggiani , Estelle Pitard , M. Carmen Romano , Luca Ciandrini