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Large graphs are natural mathematical models for describing the structure of the data in a wide variety of fields, such as web mining, social networks, information retrieval, biological networks, etc. For all these applications, automatic…

Applications · Statistics 2008-01-08 Romain Boulet , Bertrand Jouve , Fabrice Rossi , Nathalie Villa

We comprehensively studied the morphology of the self-organized effective network structures that form in simple coupled maps with interelement synchronization-dependent connection changes. Based on the parameter values, the spontaneous…

Adaptation and Self-Organizing Systems · Physics 2022-02-09 Taito Nakanishi , Masashi Fujii , Akinori Awazu

Many forms of programmable matter have been proposed for various tasks. We use an abstract model of self-organizing particle systems for programmable matter which could be used for a variety of applications, including smart paint and…

Emerging Technologies · Computer Science 2017-10-24 Alexandra Porter , Andréa W. Richa

Protein function is inherently linked to its localization within the cell, and fluorescent microscopy data is an indispensable resource for learning representations of proteins. Despite major developments in molecular representation…

Quantitative Methods · Quantitative Biology 2022-05-25 Anastasia Razdaibiedina , Alexander Brechalov

Graph clustering (or community detection) has long drawn enormous attention from the research on web mining and information networks. Recent literature on this topic has reached a consensus that node contents and link structures should be…

Social and Information Networks · Computer Science 2017-12-25 Carl Yang , Mengxiong Liu , Zongyi Wang , Liyuan Liu , Jiawei Han

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

Neurons and Cognition · Quantitative Biology 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

The biological functions of proteins often depend on dynamic structural ensembles. In this work, we develop a flow-based generative modeling approach for learning and sampling the conformational landscapes of proteins. We repurpose highly…

Biomolecules · Quantitative Biology 2024-09-04 Bowen Jing , Bonnie Berger , Tommi Jaakkola

Computational analyses of, e.g., genomic, proteomic, or metabolomic data, commonly result in one or more sets of candidate genes, proteins, or enzymes. These sets are often the outcome of clustering algorithms. Subsequently, it has to be…

Genomics · Quantitative Biology 2007-06-26 Robbe Wunschiers , Martin Vellguth

Many real-world networks are so large that we must simplify their structure before we can extract useful information about the systems they represent. As the tools for doing these simplifications proliferate within the network literature,…

Physics and Society · Physics 2015-05-13 M. Rosvall , D. Axelsson , C. T. Bergstrom

Understanding protein conformational dynamics is essential for elucidating biological function but remains challenging due to the wide range of timescales and the complexity of collective motions. Enhanced sampling methods overcome…

Statistical Mechanics · Physics 2026-05-11 Souvik Mondal , Michael A. Sauer , Matthias Heyden

An approach to improve neural network interpretability is via clusterability, i.e., splitting a model into disjoint clusters that can be studied independently. We define a measure for clusterability and show that pre-trained models form…

Machine Learning · Computer Science 2025-07-28 Satvik Golechha , Maheep Chaudhary , Joan Velja , Alessandro Abate , Nandi Schoots

Identification and alignment of three-dimensional folding of proteins may yield useful information about relationships too remote to be detected by conventional methods, such as sequence comparison, and may potentially lead to prediction of…

Quantitative Methods · Quantitative Biology 2017-01-10 Barış Ekim

Recent studies have shown how spiking networks can learn complex functionality through error-correcting plasticity, but the resulting structures and dynamics remain poorly studied. To elucidate how these models may link to observed dynamics…

Neurons and Cognition · Quantitative Biology 2025-08-19 Jonas Oberste-Frielinghaus , Anno C. Kurth , Julian Göltz , Laura Kriener , Junji Ito , Mihai A. Petrovici , Sonja Grün

Nowadays there is a multitude of measures designed to capture different aspects of network structure. To be able to say if the structure of certain network is expected or not, one needs a reference model (null model). One frequently used…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Petter Holme , Jing Zhao

Intrinsically disordered proteins and regions are increasingly appreciated for their abundance in the proteome and the many functional roles they play in the cell. In this short review, we describe a variety of approaches used to obtain…

Biological Physics · Physics 2024-12-31 Zi Hao Liu , Maria Tsanai , Oufan Zhang , Teresa Head-Gordon , Julie Forman-Kay

The description of complex configuration is a difficult issue. We present a powerful technique for cluster identification and characterization. The scheme is designed to treat with and analyze the experimental and/or simulation data from…

Statistical Mechanics · Physics 2013-08-29 Guangcai Zhang , Aiguo Xu , Guo Lu , Zeyao Mo

We propose a new self-organizing hierarchical softmax formulation for neural-network-based language models over large vocabularies. Instead of using a predefined hierarchical structure, our approach is capable of learning word clusters with…

Computation and Language · Computer Science 2017-07-29 Yikang Shen , Shawn Tan , Chrisopher Pal , Aaron Courville

Texture is one of the most important properties of visual surface that helps in discriminating one object from another or an object from background. The self-organizing map (SOM) is an excellent tool in exploratory phase of data mining. It…

Computer Vision and Pattern Recognition · Computer Science 2014-08-20 Marghny H. Mohamed , Mohammed M. Abdelsamea

In this paper it is shown how to map a data manifold into a simpler form by progressively discarding small degrees of freedom. This is the key to self-organising data fusion, where the raw data is embedded in a very high-dimensional space…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Stephen Luttrell