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Conceptual modelling using the entity relationship (ER) model has been widely used for database design for a long period of time. However, studies indicate that creating a satisfactory relational model representation from an ER model is…

Databases · Computer Science 2013-07-01 Dhammika Pieris

Elucidating principles that underlie computation in neural networks is currently a major research topic of interest in neuroscience. Transfer Entropy (TE) is increasingly used as a tool to bridge the gap between network structure, function,…

Neurons and Cognition · Quantitative Biology 2017-06-08 Madhavun Candadai Vasu , Eduardo J. Izquierdo

Our work combines aspects of three promising paradigms in machine learning, namely, attention mechanism, energy-based models, and associative memory. Attention is the power-house driving modern deep learning successes, but it lacks clear…

Metabolism is a fascinating cell machinery underlying life and disease and genome-scale reconstructions provide us with a captivating view of its complexity. However, deciphering the relationship between metabolic structure and function…

Molecular Networks · Quantitative Biology 2011-09-12 M. Angeles Serrano , Marian Boguna , Francesc Sagues

Representation learning provides new and powerful graph analytical approaches and tools for the highly valued data science challenge of mining knowledge graphs. Since previous graph analytical methods have mostly focused on homogeneous…

Information Retrieval · Computer Science 2019-05-29 Zheng Gao , Gang Fu , Chunping Ouyang , Satoshi Tsutsui , Xiaozhong Liu , Jeremy Yang , Christopher Gessner , Brian Foote , David Wild , Qi Yu , Ying Ding

Evolutionary Computation (EC) has emerged as a powerful field of Artificial Intelligence, inspired by nature's mechanisms of gradual development. However, EC approaches often face challenges such as stagnation, diversity loss, computational…

Neural and Evolutionary Computing · Computer Science 2024-02-15 Abdennour Boulesnane

We present Bionic Tracking, a novel method for solving biological cell tracking problems with eye tracking in virtual reality using commodity hardware. Using gaze data, and especially smooth pursuit eye movements, we are able to track cells…

Human-Computer Interaction · Computer Science 2020-08-04 Ulrik Günther , Kyle I. S. Harrington , Raimund Dachselt , Ivo F. Sbalzarini

Many living and non-living complex systems can be modeled and understood as collective systems made of heterogeneous components that self-organize and generate nontrivial morphological structures and behaviors. This chapter presents a brief…

Adaptation and Self-Organizing Systems · Physics 2018-01-09 Hiroki Sayama

Background: The study of genome-scale metabolic models and their underlying networks is one of the most important fields in systems biology. The complexity of these models and their description makes the use of computational tools an…

Molecular Networks · Quantitative Biology 2012-12-03 D. Gamermann , A. Montagud , R. A. Jaime Infante , J. Triana , P. F. de Córdoba , J. F. Urchueguía

Large-scale molecular representation methods have revolutionized applications in material science, such as drug discovery, chemical modeling, and material design. With the rise of transformers, models now learn representations directly from…

Computational Engineering, Finance, and Science · Computer Science 2024-10-17 Indra Priyadarsini , Seiji Takeda , Lisa Hamada , Emilio Vital Brazil , Eduardo Soares , Hajime Shinohara

It is becoming common to archive research datasets that are not only large but also numerous. In addition, their corresponding metadata and the software required to analyse or display them need to be archived. Yet the manual curation of…

Digital Libraries · Computer Science 2011-08-24 Daniel Lemire , Andre Vellino

Data-efficient image classification is a challenging task that aims to solve image classification using small training data. Neural network-based deep learning methods are effective for image classification, but they typically require…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Ying Bi , Bing Xue , Mengjie Zhang

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

The state of the art in electromagnetic Finite Element Particle-in-Cell (EM-FEMPIC) has advanced significantly in the last few years. These have included understanding function spaces that must be used to represent sources and fields…

Computational Physics · Physics 2022-08-29 Omkar H. Ramachandran , Zane D. Crawford , Scott O'Connor , John Luginsland , B. Shanker

Euler-Lagrange (EL) simulations provide a direct and robust framework for modeling disperse multiphase flows. However, they are computationally expensive. While various approaches have attempted to leverage heterogeneous computing…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Silvio Schmalfuß , Sergey Lesnik , Henrik Rusche , Dennis Niedermeier

Cells with the same genome can exist in different phenotypes. and can change between distinct phenotypes when subject to specific stimuli and microenvironments. Some examples include cell differentiation during development, reprogramming…

Quantitative Methods · Quantitative Biology 2022-09-28 Jianhua Xing

Recent advances in data-driven evolutionary algorithms (EAs) have demonstrated the potential of leveraging historical data to improve optimization accuracy and adaptability. Despite these advancements, existing methods remain reliant on…

Neural and Evolutionary Computing · Computer Science 2026-02-16 Tao Jiang , Kebin Sun , Zhenyu Liang , Ran Cheng , Yaochu Jin , Kay Chen Tan

This study facilitates the understanding of evolutionary transitions in individuality (ETIs) through a novel artificial life framework, named VitaNova, that intricately merges self-organization and natural selection to simulate the…

Populations and Evolution · Quantitative Biology 2024-09-23 Nam H. Le , Richard Watson , Mike Levin , Chrys Buckley

Large datasets represented by multidimensional data point clouds often possess non-trivial distributions with branching trajectories and excluded regions, with the recent single-cell transcriptomic studies of developing embryo being notable…

The field of evolutionary many-task optimization (EMaTO) is increasingly recognized for its ability to streamline the resolution of optimization challenges with repetitive characteristics, thereby conserving computational resources. This…

Artificial Intelligence · Computer Science 2024-07-15 Yudong Yang , Kai Wu , Xiangyi Teng , Handing Wang , He Yu , Jing Liu