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Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Motivated by biological evolution, this paper explains the rationality of Vision Transformer by analogy with the proven practical evolutionary algorithm (EA) and derives that both have consistent mathematical formulation. Then inspired by…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Jiangning Zhang , Xiangtai Li , Yabiao Wang , Chengjie Wang , Yibo Yang , Yong Liu , Dacheng Tao

The transition between epithelial and mesenchymal (EMT) is a fundamental cellular process that plays critical roles in development, cancer metastasis, and tissue wound healing. EMT is not a binary process but involves multiple partial EMT…

Cell Behavior · Quantitative Biology 2019-05-22 Jianhua Xing , Xiao-Jun Tian

Computer simulations are an important tool for studying the mechanics of biological evolution. In particular, in silico work with agent-based models provides an opportunity to collect high-quality records of ancestry relationships among…

Neural and Evolutionary Computing · Computer Science 2024-10-03 Matthew Andres Moreno , Anika Ranjan , Emily Dolson , Luis Zaman

The human brain has immense learning capabilities at extreme energy efficiencies and scale that no artificial system has been able to match. For decades, reverse engineering the brain has been one of the top priorities of science and…

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

Computation and Language · Computer Science 2020-01-07 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Since the advent of modern bioinformatics, the challenging, multifaceted problem of reconstructing phylogenetic history from biological sequences has hatched perennial statistical and algorithmic innovation. Studies of the phylogenetic…

Data Structures and Algorithms · Computer Science 2024-03-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Emily Dolson

The detection of cell shape changes in 3D time-lapse images of complex tissues is an important task. However, it is a challenging and tedious task to establish a comprehensive dataset to improve the performance of deep learning models. In…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Dali Wang , Zheng Lu , Zhirong Bao

Creating autonomous, self-supporting, self-replicating, sustainable systems is a great challenge. To some extent, understanding life means not only being able to create it from scratch, but also improving, supporting, saving it, or even…

Robotics · Computer Science 2011-11-07 Serge Kernbach

Electroencephalogram (EEG) is a common tool used to understand brain activities. The data are typically obtained by placing electrodes at the surface of the scalp and recording the oscillations of currents passing through the electrodes.…

Signal Processing · Electrical Eng. & Systems 2021-02-19 Eddy Kwessi , Lloyd Edwards

Stem cell regeneration is a vital biological process in self-renewing tissues, governing development and tissue homeostasis. Gene regulatory network dynamics are pivotal in controlling stem cell regeneration and cell type transitions.…

Molecular Networks · Quantitative Biology 2024-04-19 Yakun Li , Xiyin Liang , Jinzhi Lei

Morphogenesis of complex body shapes is reproducible despite the noise inherent in the underlying morphogenetic processes. However, how these morphogenetic processes work together to achieve this reproducibility remains unclear. Here, we…

Cell Behavior · Quantitative Biology 2025-12-24 Dominic K Devlin , Austen RD Ganley , Nobuto Takeuchi

Cross-task knowledge transfer via multi-task learning has recently made remarkable progress in general NLP tasks. However, entity tracking on the procedural text has not benefited from such knowledge transfer because of its distinct…

Computation and Language · Computer Science 2023-02-14 Janvijay Singh , Fan Bai , Zhen Wang

We formulate the search for phenomenological models of synaptic plasticity as an optimization problem. We employ Cartesian genetic programming to evolve biologically plausible human-interpretable plasticity rules that allow a given network…

Neural and Evolutionary Computing · Computer Science 2021-02-09 Henrik D. Mettler , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici , Jakob Jordan

Biotechnology offers many opportunities for the sustainable manufacturing of valuable products. The toolbox to optimize bioprocesses includes \textit{extracellular} process elements such as the bioreactor design and mode of operation,…

Systems and Control · Electrical Eng. & Systems 2023-02-07 Sebastián Espinel-Ríos , Bruno Morabito , Johannes Pohlodek , Katja Bettenbrock , Steffen Klamt , Rolf Findeisen

Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the…

Tissues and Organs · Quantitative Biology 2017-12-12 Eric D. Siggia , Aryeh Warmflash

Entity tracking (ET), the ability to keep track of states, is a fundamental skill that underlies complex reasoning. An increasing amount of work investigates how transformer language models (LMs) solve entity binding $\textit{without}$…

Computation and Language · Computer Science 2026-05-29 Zilu Tang , Qiao Zhao , Gabriel Franco , Derry Wijaya , Aaron Mueller , Sebastian Schuster , Najoung Kim

Biological plastic neural networks are systems of extraordinary computational capabilities shaped by evolution, development, and lifetime learning. The interplay of these elements leads to the emergence of adaptive behavior and…

Neural and Evolutionary Computing · Computer Science 2018-08-09 Andrea Soltoggio , Kenneth O. Stanley , Sebastian Risi

The nematode Caenorhabditis elegans (C. elegans) is used as a model organism to better understand developmental biology and neurobiology. C. elegans features an invariant cell lineage, which has been catalogued and observed using…

Computer Vision and Pattern Recognition · Computer Science 2022-08-03 Andrew Lauziere , Ryan Christensen , Hari Shroff

Designing the structure of neural networks is considered one of the most challenging tasks in deep learning, especially when there is few prior knowledge about the task domain. In this paper, we propose an Ecologically-Inspired GENetic…

Neural and Evolutionary Computing · Computer Science 2019-04-16 Jian Ren , Zhe Li , Jianchao Yang , Ning Xu , Tianbao Yang , David J. Foran
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