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Related papers: Reverse Coarse-graining for Equation-free Modeling…

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We present a novel thermodynamically guided, low-noise, time-scale bridging, and pertinently efficient strategy for the dynamic simulation of microscopic models for complex fluids. The systematic coarse-graining method is exemplified for…

Soft Condensed Matter · Physics 2010-11-12 Patrick Ilg , Hans Christian Öttinger , Martin Kröger

We developed a multiscale approach (MultiSCAAL) that integrates the potential of mean force (PMF) obtained from all-atomistic molecular dynamics simulations with a knowledge-based energy function for coarse-grained molecular simulations in…

Biological Physics · Physics 2010-05-10 Antonios Samiotakis , Dirar Homouz , Margaret S. Cheung

This paper series aims to establish a complete correspondence between fine-grained (FG) and coarse-grained (CG) dynamics by way of excess entropy scaling (introduced in Paper I). While Paper II successfully captured translational motions in…

Chemical Physics · Physics 2023-08-01 Jaehyeok Jin , Eok Kyun Lee , Gregory A. Voth

Motivated by the understanding of holography as realized in tensor networks, we develop a bulk procedure that can be interpreted as generating a sequence of coarse-grained holographic states. The coarse-graining procedure involves…

High Energy Physics - Theory · Physics 2020-10-07 Chitraang Murdia , Yasunori Nomura , Pratik Rath

We present a computer-assisted approach to coarse-graining the evolutionary dynamics of a system of nonidentical oscillators coupled through a (fixed) network structure. The existence of a spectral gap for the coupling network graph…

Statistical Mechanics · Physics 2015-05-28 Karthikeyan Rajendran , Ioannis G. Kevrekidis

Coarse-grained models have played an important role in the study of the behavior of DNA at length scales beyond a few hundred base pairs. Traditionally, these models have relied on structurally featureless and sequence-independent…

Soft Condensed Matter · Physics 2024-09-10 Enrico Skoruppa , Helmut Schiessel

The combination of high-dimensionality and disparity of time scales encountered in many problems in computational physics has motivated the development of coarse-grained (CG) models. In this paper, we advocate the paradigm of data-driven…

Computational Physics · Physics 2018-03-05 L. Felsberger , P. S. Koutsourelakis

Molecular dynamics (MD) has served as a powerful tool for designing materials with reduced reliance on laboratory testing. However, the use of MD directly to treat the deformation and failure of materials at the mesoscale is still largely…

Materials Science · Physics 2023-01-12 Huaiqian You , Xiao Xu , Yue Yu , Stewart Silling , Marta D'Elia , John Foster

Quantum geometrical molecular dynamics provides a quantum geometric picture for understanding reactive dynamics, especially excited-state conical intersection dynamics, and also a numerically exact method for strongly correlated…

Chemical Physics · Physics 2026-01-26 Mo Sha , Bing Gu

We extend our previously developed coarse-graining strategy for linear polymers with a tunable number n of effective atoms (blobs) per chain [D'Adamo et al., J. Chem. Phys. 137, 4901 (2012)] to polymer systems in thermal crossover between…

Soft Condensed Matter · Physics 2014-11-07 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

We show how the Equation-Free approach for mutliscale computations can be exploited to extract, in a computational strict and systematic way the emergent dynamical attributes, from detailed large-scale microscopic stochastic models, of…

Social and Information Networks · Computer Science 2013-10-02 Konstantinos G. Spiliotis , Constantinos I. Siettos

In molecular dynamics and sampling of high dimensional Gibbs measures coarse-graining is an important technique to reduce the dimensionality of the problem. We will study and quantify the coarse-graining error between the coarse-grained…

Analysis of PDEs · Mathematics 2020-06-04 M. H. Duong , A. Lamacz , M. A. Peletier , A. Schlichting , U. Sharma

We present an application of equation-free computation to the coarse-grained feedback linearization problem of nonlinear systems described by microscopic/stochastic simulators. Feedback linearization with pole placement requires the…

Cellular Automata and Lattice Gases · Physics 2007-05-23 C. I. Siettos , I. G. Kevrekidis , N. Kazantzis

We formulate thermodynamically consistent coarse-graining procedures for molecular systems undergoing thermally and photo-induced transitions: starting from elementary vibronic transitions, we derive effective photo-isomerization reactions…

Statistical Mechanics · Physics 2025-10-08 Francesco Avanzini , Massimiliano Esposito , Emanuele Penocchio

Identifying the relevant coarse-grained degrees of freedom in a complex physical system is a key stage in developing powerful effective theories in and out of equilibrium. The celebrated renormalization group provides a framework for this…

Statistical Mechanics · Physics 2024-11-27 Doruk Efe Gökmen , Zohar Ringel , Sebastian D. Huber , Maciej Koch-Janusz

In many stochastic simulations of biochemical reaction networks, it is desirable to ``coarse-grain'' the reaction set, removing fast reactions while retaining the correct system dynamics. Various coarse-graining methods have been proposed,…

Quantitative Methods · Quantitative Biology 2009-11-13 M. J. Morelli , R. J. Allen , S. Tanase-Nicola , P. R. ten Wolde

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

Quantitative Methods · Quantitative Biology 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

The unfolding of molecular complexes or biomolecules under the influence of external mechanical forces can routinely be simulated with atomistic resolution. To obtain a match of the characteristic time scales with those of experimental…

Soft Condensed Matter · Physics 2024-07-17 Marco Oestereich , Jürgen Gauss , Gregor Diezemann

In this report we introduce the basic techniques (of the Closed Time Path - Coarse Grained Effective Action CTP-CGEA) and ideas (scaling, coarse-graining and backreaction) behind the treatment of quantum processes in dynamical background…

High Energy Physics - Theory · Physics 2008-11-26 Esteban A. Calzetta , Bei Lok Hu , Francisco D. Mazzitelli

We present a new adaptive resolution technique for efficient particle-based multiscale molecular dynamics (MD) simulations. The presented approach is tailor-made for molecular systems where atomistic resolution is required only in spatially…

Soft Condensed Matter · Physics 2007-05-23 Matej Praprotnik , Luigi Delle Site , Kurt Kremer