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The organism is a fundamental concept in biology. However there is no universally accepted, formal, and yet broadly applicable definition of what an organism is. Here we introduce a candidate definition. We adopt the view that the…

Other Quantitative Biology · Quantitative Biology 2016-12-02 Eric Libby , Joshua Grochow , Simon DeDeo , David Wolpert

High-throughput experiments are shedding light on the topology of large regulatory networks and at the same time their functional states, namely the states of activation of the nodes (for example transcript or protein levels) in different…

Molecular Networks · Quantitative Biology 2009-02-13 M. Cosentino Lagomarsino , B. Bassetti , G. Castellani , D. Remondini

This manuscript contains nothing new, but synthesizes known results: For the theoretical population geneticist with a probabilistic background, we provide a summary of some key results on stochastic differential equations. For the…

Populations and Evolution · Quantitative Biology 2020-08-25 Peter Czuppon , Arne Traulsen

Although deep reinforcement learning has become a promising machine learning approach for sequential decision-making problems, it is still not mature enough for high-stake domains such as autonomous driving or medical applications. In such…

Machine Learning · Computer Science 2022-02-25 Claire Glanois , Paul Weng , Matthieu Zimmer , Dong Li , Tianpei Yang , Jianye Hao , Wulong Liu

Several researchers have argued that a machine learning system's interpretability should be defined in relation to a specific agent or task: we should not ask if the system is interpretable, but to whom is it interpretable. We describe a…

Artificial Intelligence · Computer Science 2018-06-21 Richard Tomsett , Dave Braines , Dan Harborne , Alun Preece , Supriyo Chakraborty

In recent years, the field of neuroscience has gone through rapid experimental advances and a significant increase in the use of quantitative and computational methods. This growth has created a need for clearer analyses of the theory and…

With the adoption of machine learning-based solutions in routine clinical practice, the need for reliable interpretability tools has become pressing. Shapley values provide local explanations. The method gained popularity in recent years.…

Methodology · Statistics 2023-06-27 Lucile Ter-Minassian , Sahra Ghalebikesabi , Karla Diaz-Ordaz , Chris Holmes

This PhD thesis is essentially the story of a scientific idea, from what it has blossomed, how it has grown, what it might become. My ambition in writing has been to produce an original, coherent and compact narrative. It begins (1) with a…

Biological Physics · Physics 2023-12-25 Vito Dichio

Eco-evolutionary game dynamics which characterizes the mutual interactions and the coupled evolutions of strategies and environments has been of growing interests in very recent years. Since such feedback loops widely exist in a range of…

Physics and Society · Physics 2021-02-03 Xin Wang , Feng Fu

Understanding transformer-based language models is becoming increasingly crucial, particularly as they play pivotal roles in advancing towards artificial general intelligence. However, language model research faces significant challenges,…

Computation and Language · Computer Science 2024-01-17 Zhongwang Zhang , Zhiwei Wang , Junjie Yao , Zhangchen Zhou , Xiaolong Li , Weinan E , Zhi-Qin John Xu

Evolutionary and bioinspired computation are crucial for efficiently addressing complex optimization problems across diverse application domains. By mimicking processes observed in nature, like evolution itself, these algorithms offer…

Neural and Evolutionary Computing · Computer Science 2025-01-14 Daniel Molina , Javier Del Ser , Javier Poyatos , Francisco Herrera

Life forms exhibit such a degree of exquisite organization that it seems impossible that they could have developed out of a process of trial and error, as intimated by the theory of Darwinian evolution. In this general public paper I…

Populations and Evolution · Quantitative Biology 2019-01-08 Luca Peliti

We consider the problem of finding plausible knowledge that is missing from a given ontology, as a generalisation of the well-studied taxonomy expansion task. One line of work treats this task as a Natural Language Inference (NLI) problem,…

Computation and Language · Computer Science 2024-03-27 Na Li , Thomas Bailleux , Zied Bouraoui , Steven Schockaert

This paper studies the role that ontologies can play in establishing conceptual data models during the process of information systems development. A mapping algorithm has been proposed and embedded in a special purpose Transformation-Engine…

Software Engineering · Computer Science 2007-05-23 Haya El-Ghalayini , Mohammed Odeh , Richard McClatchey

Evolutionary algorithm research and applications began over 50 years ago. Like other artificial intelligence techniques, evolutionary algorithms will likely see increased use and development due to the increased availability of computation,…

Neural and Evolutionary Computing · Computer Science 2019-06-24 Andrew N. Sloss , Steven Gustafson

We develop a rigorous, equation-free category-theoretic foundation for fungal organisation. A fungal organism is formalised as a functor from a category $\Env$ of structured environmental states and admissible transformations to a category…

Emerging Technologies · Computer Science 2026-03-03 Andrew Adamatzky

An automorphism defined on an evolution algebra can provide both a finite number and an infinite number of evolution operators on it. This question is dealt with in the paper, as well as others more related to the evolution operators of…

Rings and Algebras · Mathematics 2023-01-23 Desamparados Fernández-Ternero , Víctor M. Gómez-Sousa , Juan Núñez-Valdés

Through extensive experience developing and explaining machine learning (ML) applications for real-world domains, we have learned that ML models are only as interpretable as their features. Even simple, highly interpretable model types such…

Machine Learning · Computer Science 2022-02-25 Alexandra Zytek , Ignacio Arnaldo , Dongyu Liu , Laure Berti-Equille , Kalyan Veeramachaneni

Mixed microbial communities, usually composed of various bacterial and fungal species, are fundamental in a plethora of environments, from soil to human gut and skin. Their evolution is a paradigmatic example of intertwined dynamics, where…

Populations and Evolution · Quantitative Biology 2022-07-01 Andrea Roli , Stuart A. Kauffman

Evolution Strategies are inspired in biology and part of a larger research field known as Evolutionary Algorithms. Those strategies perform a random search in the space of admissible functions, aiming to optimize some given objective…

Optimization and Control · Mathematics 2007-12-30 Pedro A. F. Cruz , Delfim F. M. Torres
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