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In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…
The human brain is liable to undergo substantial alterations, anatomically and functionally with aging. Cognitive brain aging can either be healthy or degenerative in nature. Such degeneration of cognitive ability can lead to disorders such…
Pathophysiolpgical modelling of brain systems from microscale to macroscale remains difficult in group comparisons partly because of the infeasibility of modelling the interactions of thousands of neurons at the scales involved. Here, to…
A method for the quantitative assessment of spatio-temporal structuring of brain activity is presented. This approach is employed in a longitudinal case study of a child with frontal lobe epilepsy (FLE) and tested against an age-matched…
A unique feature of neuromorphic computing is that memory is an implicit part of processing through traces of past information in the system's collective dynamics. The extent of memory about past inputs is commonly quantified by the…
While differences in patterns of functional connectivity and neural synchronization have been reported between individuals on the autism spectrum and neurotypical peers at various age stages, these differences appear to be subtle and may…
Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…
The human neocortex is functionally organised at its highest level along a continuous sensory-to-association (AS) hierarchy. This study characterises the AS hierarchy of patients with schizophrenia in a comparison with controls. Using a…
In this paper, the brain functional networks derived from high-resolution synchronous EEG time series during visual task are generated by calculating the phase synchronization among the time series. The hierarchical modular organizations of…
Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…
Epilepsy is one of the most prevalent neurological conditions, where an epileptic seizure is a transient occurrence due to abnormal, excessive and synchronous activity in the brain. Electroencephalogram signals emanating from the brain may…
Neurons in the brain are wired into adaptive networks that exhibit a range of collective dynamics. Oscillations, for example, are paradigmatic synchronous patterns of neural activity with a defined temporal scale. Neuronal avalanches, in…
Whole-brain models offer a promising method of predicting seizure spread, which is critical for successful surgery treatment of focal epilepsy. Existing methods are largely based on structural connectome, which ignores the effects of…
The field of study of complex systems holds that the dynamics of complex systems are founded on universal principles that may used to describe a great variety of scientific and technological approaches of different types of natural,…
Epilepsy, affecting approximately 50 million people globally, is characterized by abnormal brain activity and remains challenging to treat. The diagnosis of epilepsy relies heavily on electroencephalogram (EEG) data, where specialists…
We consider the electrical signals recorded from a subdural array of electrodes placed on the pial surface of the brain for chronic evaluation of epileptic patients before surgical resection. A simple and computationally fast method to…
Qualitatively, some real networks in the brain could be characterized as 'small worlds', in the sense that the structure of their connections is intermediate between the extremes of an orderly geometric arrangement and of a…
Detecting seizure using brain neuroactivations recorded by intracranial electroencephalogram (iEEG) has been widely used for monitoring, diagnosing, and closed-loop therapy of epileptic patients, however, computational efficiency gains are…
Scale-invariant neuronal avalanches have been observed in cell cultures and slices as well as anesthetized and awake brains, suggesting that the brain operates near criticality, i.e. within a narrow margin between avalanche propagation and…
We calculate a measure of statistical complexity from the global dynamics of electroencephalographic (EEG) signals from healthy subjects and epileptic patients, and are able to stablish a criterion to characterize the collective behavior in…