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Large-scale simulation optimization (SO) problems encompass both large-scale ranking-and-selection problems and high-dimensional discrete or continuous SO problems, presenting significant challenges to existing SO theories and algorithms.…

Optimization and Control · Mathematics 2024-03-26 Weiwei Fan , L. Jeff Hong , Guangxin Jiang , Jun Luo

Simulators are the most dominant and eminent tool for analyzing and investigating different type of networks. The simulations can be executed with less cost as compared to large scale experiment as less computational resources are required…

Networking and Internet Architecture · Computer Science 2014-05-05 Mansoor Ebrahim , Shujaat Khan , Syed Sheraz Ul Hasan Mohani

Bayesian synthetic likelihood (BSL) is a popular method for estimating the parameter posterior distribution for complex statistical models and stochastic processes that possess a computationally intractable likelihood function. Instead of…

Computation · Statistics 2019-07-26 Ziwen An , Leah F South , Christopher Drovandi

Semi-competing risks refer to the setting where primary scientific interest lies in estimation and inference with respect to a non-terminal event, the occurrence of which is subject to a terminal event. In this paper, we present the R…

Computation · Statistics 2018-04-06 Danilo Alvares , Sebastien Haneuse , Catherine Lee , Kyu Ha Lee

There are enormous amount of examples of Computation in nature, exemplified across multiple species in biology. One crucial aim for these computations across all life forms their ability to learn and thereby increase the chance of their…

Machine Learning · Computer Science 2013-12-30 Nabarun Mondal , Partha P. Ghosh

Measurement error in a covariate or the outcome of regression models is common, but is often ignored, even though measurement error can lead to substantial bias in the estimated covariate-outcome association. While several texts on…

Methodology · Statistics 2021-02-10 Linda Nab , Maarten van Smeden , Ruth H. Keogh , Rolf H. H. Groenwold

We introduce the R package ContaminatedMixt, conceived to disseminate the use of mixtures of multivariate contaminated normal distributions as a tool for robust clustering and classification under the common assumption of elliptically…

Computation · Statistics 2016-06-14 Antonio Punzo , Angelo Mazza , Paul D. McNicholas

R is a language and computing environment that has been developed for data manipulation, statistical computing, and scientific graphing. In the paper, we demonstrate its use analyzing data collected in a few experiments taken from an…

Physics Education · Physics 2009-11-25 Primoz Peterlin

The Causal Roadmap outlines a systematic approach to asking and answering questions of cause-and-effect: define the quantity of interest, evaluate needed assumptions, conduct statistical estimation, and carefully interpret results. To…

Methodology · Statistics 2024-05-30 Nerissa Nance , Maya L. Petersen , Mark van der Laan , Laura B. Balzer

Scientific knowledge expands by observing the world, hypothesizing some theories about it, and testing them against collected data. When those theories take the form of statistical models, statistical analyses are involved in the process of…

Machine Learning · Statistics 2026-03-11 Arnaud Delaunoy

Context: It has been argued that software engineering replications are useful for verifying the results of previous experiments. However, it has not yet been agreed how to check whether the results hold across replications. Besides, some…

Software Engineering · Computer Science 2020-11-06 Adrian Santos , Sira Vegas , Markku Oivo , Natalia Juristo

Advancements in medical informatics tools and high-throughput biological experimentation make large-scale biomedical data routinely accessible to researchers. Competing risks data are typical in biomedical studies where individuals are at…

Computation · Statistics 2021-11-30 Eric S Kawaguchi , Jenny I Shen , Gang Li , Marc A Suchard

Background. The bootComb R package allows researchers to derive confidence intervals with correct target coverage for arbitrary combinations of arbitrary numbers of independently estimated parameters. Previous versions (< 1.1.0) of bootComb…

Methodology · Statistics 2022-10-03 Marc Yves Romain Henrion

Simulation has emerged as a popular method to study the long-term societal consequences of recommender systems. This approach allows researchers to specify their theoretical model explicitly and observe the evolution of system-level…

Computers and Society · Computer Science 2021-07-29 Eli Lucherini , Matthew Sun , Amy Winecoff , Arvind Narayanan

We describe the \proglang{R} package \pkg{glmmrBase} and an extension \pkg{glmmrOptim}. \pkg{glmmrBase} provides a flexible approach to specifying, fitting, and analysing generalised linear mixed models. We use an object-orientated class…

Computation · Statistics 2024-03-15 Samuel I. Watson

The simmer package brings discrete-event simulation to R. It is designed as a generic yet powerful process-oriented framework. The architecture encloses a robust and fast simulation core written in C++ with automatic monitoring…

Computation · Statistics 2019-08-02 Iñaki Ucar , Bart Smeets , Arturo Azcorra

Designing scalable estimation algorithms is a core challenge in modern statistics. Here we introduce a framework to address this challenge based on parallel approximants, which yields estimators with provable properties that operate on the…

Methodology · Statistics 2023-08-04 Aritra Chakravorty , William S. Cleveland , Patrick J. Wolfe

The matched case-control design, up until recently mostly pertinent to epidemiological studies, is becoming customary in biomedical applications as well. For instance, in omics studies, it is quite common to compare cancer and healthy…

Methodology · Statistics 2024-02-05 Vera Djordjilović , Erica Ponzi , Therese Haugdahl Nøst , Magne Thoresen

There are billions of lines of sequential code inside nowadays' software which do not benefit from the parallelism available in modern multicore architectures. Automatically parallelizing sequential code, to promote an efficient use of the…

Programming Languages · Computer Science 2016-04-13 Alcides Fonseca , Bruno Cabral , João Rafael , Ivo Correia

Large-scale observational health databases are increasingly popular for conducting comparative effectiveness and safety studies of medical products. However, increasing number of patients poses computational challenges when fitting survival…

Computation · Statistics 2023-10-26 Jianxiao Yang , Martijn J. Schuemie , Xiang Ji , Marc A. Suchard