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Optical endoscopy plays a crucial role in minimally invasive medical diagnostics and therapeutic procedures. Nonetheless, state-of-the-art endoscopic zoom objectives are bulky, requiring multi-element lens actuation, which can limit…

Manipulating the propagation of light through scattering media remains a major challenge for many applications, including astronomy, biomedical imaging and colloidal optics. Wavefront shaping is one of the most promising ways to mitigate…

Neuroprostheses show potential in restoring lost sensory function and enhancing human capabilities, but the sensations produced by current devices often seem unnatural or distorted. Exact placement of implants and differences in individual…

Neurons and Cognition · Quantitative Biology 2023-10-31 Jacob Granley , Tristan Fauvel , Matthew Chalk , Michael Beyeler

Ultrasound B-Mode images are created from data obtained from each element in the transducer array in a process called beamforming. The beamforming goal is to enhance signals from specified spatial locations, while reducing signal from all…

Signal Processing · Electrical Eng. & Systems 2020-07-08 Jaime Tierney , Adam Luchies , Christopher Khan , Brett Byram , Matthew Berger

Quantum imaging employs the nonclassical correlation of photons to break through the noise limitation of classical imaging, realizing high sensitivity, high SNR imaging and multifunctional image processing. To enhance the flexibility and…

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

We consider deep learning strategies in ultrasound systems, from the front-end to advanced applications. Our goal is to provide the reader with a broad understanding of the possible impact of deep learning methodologies on many aspects of…

Signal Processing · Electrical Eng. & Systems 2019-07-30 Ruud JG van Sloun , Regev Cohen , Yonina C Eldar

Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…

Photoacoustic microscopy (PAM) is a promising imaging modality because it is able to reveal optical absorption contrast in high resolution on the order of a micrometer. It can be applied in an endoscopic approach by implementing PAM into a…

Medical Physics · Physics 2019-11-22 Zhendong Guo , Zhanhong Ye , Weihao Shao , Lili Jing , Sung-Liang Chen

Fluoroscopy is critical for real-time X-ray visualization in medical imaging. However, low-dose images are compromised by noise, potentially affecting diagnostic accuracy. Noise reduction is crucial for maintaining image quality, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Sun-Young Jeon , Sen Wang , Adam S. Wang , Garry E. Gold , Jang-Hwan Choi

The suggestive idea of "cloaking" an electromagnetic sensor, i.e., strongly reducing its visibility (scattering) while maintaining its field-sensing (absorption) capabilities, has recently been proposed in the literature, based on…

Light scattering limits the penetration depth of non-invasive Raman spectroscopy in biological media. While safe levels of irradiation may be adequate to analyze superficial tissue, scattering of the pump beam reduces the Raman signal to…

The development of robust, real-time optical methods for the detection and tracking of particles in complex multiple scattering media is a problem of practical importance in a number of fields, including environmental monitoring, air…

Optics · Physics 2025-02-04 Mohammadrasoul Taghavi , Edwin A. Marengo

Control over intensity, shape, direction, and phase of coherent light is essential in numerous fields, reaching from gravitational wave astronomy over quantum metrology and ultrafast sciences to semi-conductor fabrication. Modern laser…

Imaging through complex scattering media is severely limited by aberrations and scattering which obscure images and reduce resolution. Confocal and temporal gatings partly filter out multiple scattering but are severely degraded by…

Optics · Physics 2026-05-18 Yiwen Zhang , Minh Dinh , Zeyu Wang , Tianhao Zhang , Tianhang Chen , Chia Wei Hsu

Extending super-resolution imaging techniques to objects hidden in strongly scattering media potentially revolutionize the technical analysis for much broader categories of samples, such as biological tissues. The main challenge is the…

Score-based diffusion models are a recently developed framework for posterior sampling in Bayesian inverse problems with a state-of-the-art performance for severely ill-posed problems by leveraging a powerful prior distribution learned from…

Optical biosensors are indispensable in medical and environmental diagnostics, yet existing approaches are fundamentally limited in their sensitivity due to ensemble-averaged measurements. Digital biosensing has emerged as a promising…

The recent advent of wave-shaping methods has demonstrated the focusing of light through and inside even the most strongly scattering materials. Typically in wavefront shaping, light is focused in an area with the size of one speckle spot.…