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We study the adaptation dynamics of an initially maladapted asexual population with genotypes represented by binary sequences of length $L$. The population evolves in a maximally rugged fitness landscape with a large number of local optima.…

Populations and Evolution · Quantitative Biology 2007-05-23 Kavita Jain , Joachim Krug

We consider a simple mathematical model of gradual Darwinian evolution in continuous time and continuous trait space, due to intraspecific competition for common resource in an asexually reproducing population in constant environment, while…

Populations and Evolution · Quantitative Biology 2014-03-27 Vadim N. Biktashev

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

Using information theory, we propose an estimation method for traits parameters in a Darwinian evolution model for species with on trait or multiple traits. We use the Fisher's information to obtain the errors on the estimation for one…

Populations and Evolution · Quantitative Biology 2024-03-11 Eddy Kwessi

We study the evolution of large but finite asexual populations evolving in fitness landscapes in which all mutations are either neutral or strongly deleterious. We demonstrate that despite the absence of higher fitness genotypes, adaptation…

Biological Physics · Physics 2007-05-23 Claus O. Wilke

We study the evolution of the probability density of an asexual, one locus population under natural selection and random evolution. This evolution is governed by a Fokker-Planck equation with degenerate coefficients on the boundaries,…

Analysis of PDEs · Mathematics 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

These lectures contain a brief description of evolutionary models inspired by the statistical mechanics of disordered systems. After an introduction describing the Darwinian paradigm of evolving populations, the deterministic quasispecies…

Disordered Systems and Neural Networks · Physics 2007-05-23 Luca Peliti

We consider a linear size-structured population model with diffusion in the size-space. Individuals are recruited into the population at arbitrary sizes. The model is equipped with generalized Wentzell-Robin (or dynamic) boundary…

Analysis of PDEs · Mathematics 2019-03-25 J. Z. Farkas , P. Hinow

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

An ongoing debate in evolutionary biology is whether phenotypic change occurs predominantly around the time of speciation or whether it instead accumulates gradually over time. In this work I propose a general framework incorporating both…

Populations and Evolution · Quantitative Biology 2014-07-02 Krzysztof Bartoszek

In the context of global warming, tree populations rely on two primary mechanisms of adaptation: phenotypic plasticity, which enables individuals to adjust their behavior in response to environmental stress, and genetic evolution, driven by…

Populations and Evolution · Quantitative Biology 2026-01-27 Sirine Boucenna , Vasilis Dakos , Gaël Raoul

In sustained growth with random dynamics stationary distributions can exist without detailed balance. This suggests thermodynamical behavior in fast growing complex systems. In order to model such phenomena we apply both a discrete and a…

Statistical Mechanics · Physics 2017-03-22 Tamás Biró , Zoltán Néda

Biological evolution can be conceptualized as a search process in the space of gene sequences guided by the fitness landscape, a mapping that assigns a measure of reproductive value to each genotype. Here we discuss probabilistic models of…

Populations and Evolution · Quantitative Biology 2024-04-10 Joachim Krug , Daniel Oros

We consider population models in which the individuals reproduce, die and also migrate in space. The population size scales according to some parameter $N$, which can have different interpretations depending on the context. Each individual…

Probability · Mathematics 2012-12-21 Ankit Gupta

A key question in evolution is how likely a mutant is to take over. This depends on natural selection and on stochastic fluctuations. Population spatial structure can impact mutant fixation probabilities. We introduce a model for structured…

Populations and Evolution · Quantitative Biology 2021-11-23 Loïc Marrec , Irene Lamberti , Anne-Florence Bitbol

Recent work on mutation-selection models has revealed that, under specific assumptions on the fitness function and the mutation rates, asymptotic estimates for the leading eigenvalue of the mutation-reproduction matrix may be obtained…

Populations and Evolution · Quantitative Biology 2007-05-23 E. Baake , M. Baake , A. Bovier , M. Klein

When studying the dynamics of trait distribution of populations in a heterogeneous environment, classical models from quantitative genetics choose to look at its system of moments, specifically the first two ones. Additionally, in order to…

Populations and Evolution · Quantitative Biology 2020-12-21 Léonard Dekens

We study an equation structured by age and a phenotypic trait describing the growth process of a population subject to aging, competition between individuals, and mutations. This leads to a renewal equation which occurs in many evolutionary…

Analysis of PDEs · Mathematics 2020-01-14 Samuel Nordmann , Benoît Perthame

We present an SI epidemic model whereby a continuous variable captures variability in proliferative potential and resistance to infection among susceptibles. The occurrence of heritable, spontaneous changes in these phenotype and the…

Populations and Evolution · Quantitative Biology 2021-12-30 Tommaso Lorenzi , Andrea Pugliese , Mattia Sensi , Agnese Zardini
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