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Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Youssef S. G. Nashed , Frederic Poitevin , Harshit Gupta , Geoffrey Woollard , Michael Kagan , Chuck Yoon , Daniel Ratner

The research on recognizing the most discriminative regions provides referential information for weakly supervised object localization with only image-level annotations. However, the most discriminative regions usually conceal the other…

Computer Vision and Pattern Recognition · Computer Science 2019-09-12 Yukun Zhou , Zailiang Chen , Hailan Shen , Qing Liu , Rongchang Zhao , Yixiong Liang

The goal of cryo-electron microscopy (EM) is to reconstruct the 3-dimensional structure of a molecule from a collection of its 2-dimensional projected images. In this article, we show that the basic premise of cryo-EM --- patching together…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Ke Ye , Lek-Heng Lim

We present a new analysis method for atomic resolution four-dimensional scanning transmission electron microscopy (4D-STEM, in which a diffraction pattern is collected at each point of a raster scan of a focused electron beam across the…

Instrumentation and Detectors · Physics 2025-08-11 Yining Xie , Eoin Moynihan , Marin Alexe , Louis Piper , Ana Sanchez , Richard Beanland

We present a dual cut-off, dc-tunable low-pass microwave filter on a superconducting Nb microstrip with uniaxial asymmetric nanogrooves. The frequency response of the device was measured in the range $300$\,KHz to $14$\,GHz at different…

Superconductivity · Physics 2017-05-01 Oleksandr V. Dobrovolskiy , Michael Huth

Executing multiple tasks simultaneously in medical image analysis, including segmentation, classification, detection, and regression, often introduces significant challenges regarding model generalizability and the optimization of shared…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hui Wan , Libin Lan

Low-dose computed tomography (LDCT) is the current standard for lung cancer screening, yet its adoption and accessibility remain limited. Many regions lack LDCT infrastructure, and even among those screened, early-stage cancer detection…

Medical Physics · Physics 2025-11-03 Joyoni Dey , Hunter C. Meyer , Murtuza S. Taqi

One-dimensional photonic crystals (1DPCs) are widely used platforms for guiding, filtering, and enhancing light at the nanoscale. Traditionally, designs have favored high refractive index contrast to maximize the photonic band gap (PBG)…

Dual energy computerized tomography has gained great interest because of its ability to characterize the chemical composition of a material rather than simply providing relative attenuation images as in conventional tomography. The purpose…

Computer Vision and Pattern Recognition · Computer Science 2015-05-27 Oguz Semerci , Eric L. Miller

Fine-grained image retrieval (FGIR) is to learn visual representations that distinguish visually similar objects while maintaining generalization. Existing methods propose to generate discriminative features, but rarely consider the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Xin Jiang , Hao Tang , Rui Yan , Jinhui Tang , Zechao Li

Due to its favorable computational efficiency time-dependent (TD) density functional theory (DFT) enables the prediction of electronic spectra in a high-throughput manner across chemical space. Its predictions, however, can be quite…

Image denoising is a fundamental challenge in computer vision, with applications in photography and medical imaging. While deep learning-based methods have shown remarkable success, their reliance on specific noise distributions limits…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Dongjin Kim , Jaekyun Ko , Muhammad Kashif Ali , Tae Hyun Kim

Recently, Rydberg atom has emerged as an attractive choice to realize quantum sensing of low-frequency electric field. The progress so far has mostly utilized the intensity and phase changes in probe laser and the corresponding detection…

Atomic Physics · Physics 2026-03-11 Ding Wang , Shenchao Jin , Xiayang Fan , Hongjing Li , Jiatian Liu , Jingzheng Huang , Guihua Zeng , Yuan Sun

Over the past decade, cryogenic electron microscopy (cryo-EM) has emerged as a primary method for determining near-native, near-atomic resolution 3D structures of biological macromolecules. In order to meet increasing demand for cryo-EM,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Paul T. Kim , Alex J. Noble , Anchi Cheng , Tristan Bepler

Traditional image acquisition for cryo focused ion-beam scanning electron microscopy tomography often sees thousands of images being captured over a period of many hours, with immense data sets being produced. When imaging beam sensitive…

We report on a new algorithm for detection of crystallographic information in 3D, as retained in Atom Probe Tomography (APT), with improved robustness and signal detection performance. The algorithm is underpinned by 1D distribution…

Materials Science · Physics 2019-05-22 Daniel Haley , Paul A. J. Bagot , Michael P. Moody

In recent years, Electroencephalographic analysis has gained prominence in stress research when combined with AI and Machine Learning models for validation. In this study, a lightweight dynamic brain connectivity framework based on Time…

Neurons and Cognition · Quantitative Biology 2025-11-11 Sayantan Acharya , Abbas Khosravi , Douglas Creighton , Roohallah Alizadehsani , U. Rajendra Acharya

In automatic target recognition (ATR) systems, sensors may fail to capture discriminative, fine-grained detail features due to environmental conditions, noise created by CMOS chips, occlusion, parallaxes, and sensor misalignment. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Shoaib Meraj Sami , Md Mahedi Hasan , Nasser M. Nasrabadi , Raghuveer Rao

Particle picking is a crucial first step in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM). Selecting particles from the micrographs is difficult especially for small particles with low contrast. As…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Ayelet Heimowitz , Joakim Andén , Amit Singer

Harnessing the potential wide-ranging quantum science applications of molecules will require control of their interactions. Here, we use microwave radiation to directly engineer and tune the interaction potentials between ultracold calcium…

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