Related papers: nuSTORM Project Definition Report
A novel probabilistic approach for the design of mechanical structures with friction interfaces is proposed. The objective function is defined as the probability that a specified performance measure of the forced vibration response is…
Estimation of quantum states is one of the most important steps in any quantum information processing experiment. A naive reconstruction of the density matrix from experimental measurements can often give density matrices which are not…
We propose a function-valued evaluation metric for generative models based on the relative density ratio (RDR) designed to characterize distributional differences between real and generated samples. As an evaluation metric, the RDR function…
The BioNLP Workshop 2023 initiated the launch of a shared task on Problem List Summarization (ProbSum) in January 2023. The aim of this shared task is to attract future research efforts in building NLP models for real-world diagnostic…
We summarize the status of Deep Underground Neutrino Experiment (DUNE) Offline Software and Computing program. We describe plans for the computing infrastructure needed to acquire, catalog, reconstruct, simulate and analyze the data from…
The Proton EDM Experiment (pEDM) is the first direct search for the proton electric dipole moment (EDM) with the aim of being the first experiment to probe the Standard Model (SM) prediction of any particle EDM. Phase-I of pEDM will achieve…
Differential expression (DE) analysis is a key task in RNA-seq studies, aiming to identify genes with expression differences across conditions. A central challenge is balancing false discovery rate (FDR) control with statistical power.…
This document is the second in a series of reports on the exciting physics that would be accessible at Fermilab in the event of an upgraded proton source. Where the first report covered a broad range of topics, this report focuses…
In this work, we address a foundational question in the theoretical analysis of the Deep Ritz Method (DRM) under the over-parameteriztion regime: Given a target precision level, how can one determine the appropriate number of training…
Quasi-experimental evaluations are central for generating real-world causal evidence and complementing insights from randomized trials. The regression discontinuity design (RDD) is a quasi-experimental design that can be used to estimate…
Exploratory testing is neither black nor white, but rather a continuum of exploration exists. In this research we propose an approach for decision support helping practitioners to distribute time between different degrees of exploratory…
The materials engineering data base relevant to fusion irradiation is poorly populated and it has long been recognized that a fusion spectrum neutron source will be required, the facility IFMIF being the present proposal. Re- evaluation of…
Reward modeling is essential for aligning Large Language Models(LLMs) with human preferences, yet conventional reward models suffer from poor interpretability and heavy reliance on costly expert annotations. While recent rubric-based…
Fast and accurate protein structure prediction is one of the major challenges in structural biology, biotechnology and molecular biomedicine. These fields require 3D protein structures for rational design of proteins with improved or novel…
The US Food and Drug Administration launched Project Optimus with the aim of shifting the paradigm of dose-finding and selection towards identifying the optimal biological dose that offers the best balance between benefit and risk, rather…
Machine-learning models have demonstrated great success in learning complex patterns that enable them to make predictions about unobserved data. In addition to using models for prediction, the ability to interpret what a model has learned…
Intrinsically disordered regions (IDRs) play central roles in cellular function, yet remain poorly evaluated by existing protein structure prediction benchmarks. Current evaluations largely focus on well-folded domains, overlooking three…
We present the design of a next-generation experiment, n2EDM, currently under construction at the ultracold neutron source at the Paul Scherrer Institute (PSI) with the aim of carrying out a high-precision search for an electric dipole…
Motivation: In microarray analysis, special consideration must be given to the issues of multiple statistical tests and typically p-values are adjusted to control family-wise error rate (FWER) or false discovery rate (FDR). FDR metrics have…
DUNE is a new international experiment for neutrino physics and nucleon decay searches. It will consist of two detectors, about 1300 km apart, exposed to a multi-megawatt neutrino beam that will be built at Fermilab. One of the two…