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This paper presents a new algorithm for calculating hash signatures of sets which can be directly used for Jaccard similarity estimation. The new approach is an improvement over the MinHash algorithm, because it has a better runtime…

Data Structures and Algorithms · Computer Science 2017-06-20 Otmar Ertl

This thesis investigates the design of algorithms for solving min-max optimization problems, which form the mathematical foundation of many modern applications in machine learning, game theory, and optimization. This work offers new…

Optimization and Control · Mathematics 2025-12-16 Sayantan Choudhury

In the last decade the broad scope of complex networks has led to a rapid progress. In this area a particular interest has the study of community structures. The analysis of this type of structure requires the formalization of the intuitive…

Information Retrieval · Computer Science 2009-12-07 Vincenza Carchiolo , Alessandro Longheu , Michele Malgeri , Giuseppe Mangioni

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution, which are characterized by successfully finding robust solutions for optimization problems. Here, we propose a subroutine-based quantum genetic…

Quantum Physics · Physics 2024-06-07 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz

Recent work has shown that energy-based language modeling is an effective framework for controllable text generation because it enables flexible integration of arbitrary discriminators. However, because energy-based LMs are globally…

Computation and Language · Computer Science 2023-12-08 Jarad Forristal , Niloofar Mireshghallah , Greg Durrett , Taylor Berg-Kirkpatrick

We have developed a novel method to rapidly obtain homologous genomic data for phylogenetics directly from next-generation sequencing reads without the use of a reference genome. This software, called SISRS, avoids the time consuming steps…

Populations and Evolution · Quantitative Biology 2015-06-12 Rachel S. Schwartz , Kelly Harkins , Anne C. Stone , Reed A. Cartwright

Identification of functional elements of a genome often requires dividing a sequence of measurements along a genome into segments differing from adjacent segments. In many applications, the mean of the measured values at multiple genomic…

Applications · Statistics 2015-06-30 S. B. Girimurugan , Jonathan Dennis , Jinfeng Zhang

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

Machine Learning · Computer Science 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome. Haplotype information is essential in unravelling the…

Genomics · Quantitative Biology 2020-06-19 Sina Majidian , Mohammad Hossein Kahaei , Dick de Ridder

Despite advances in feature representation, leveraging geometric relations is crucial for establishing reliable visual correspondences under large variations of images. In this work we introduce a Hough transform perspective on…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Juhong Min , Minsu Cho

This study introduces an innovative crossover operator named Particle Swarm Optimization-inspired Crossover (PSOX), which is specifically developed for real-coded genetic algorithms. Departing from conventional crossover approaches that…

Neural and Evolutionary Computing · Computer Science 2025-05-07 Xiaobo Jin , JiaShu Tu

Affordable, high-quality whole-genome assemblies have made it possible to construct rich pangenomes that capture haplotype diversity across many species. As these datasets grow, they motivate the development of specialized techniques…

Genomics · Quantitative Biology 2025-12-19 Gorkem Kadir Solun , Ugur Dogrusoz

Code search is to search reusable code snippets from source code corpus based on natural languages queries. Deep learning-based methods of code search have shown promising results. However, previous methods focus on retrieval accuracy but…

Software Engineering · Computer Science 2022-04-01 Wenchao Gu , Yanlin Wang , Lun Du , Hongyu Zhang , Shi Han , Dongmei Zhang , Michael R. Lyu

Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption…

Genomics · Quantitative Biology 2014-02-28 Ka-Kit Lam , Asif Khalak , David Tse

Genome assembly is a prominent problem studied in bioinformatics, which computes the source string using a set of its overlapping substrings. Classically, genome assembly uses assembly graphs built using this set of substrings to compute…

Data Structures and Algorithms · Computer Science 2024-09-24 Saumya Talera , Parth Bansal , Shabnam Khan , Shahbaz Khan

Cross-modal hashing is a successful method to solve large-scale multimedia retrieval issue. A lot of matrix factorization-based hashing methods are proposed. However, the existing methods still struggle with a few problems, such as how to…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Wenyun Li , Chi-Man Pun

With the development of high throughput sequencing technology, it becomes possible to directly analyze mutation distribution in a genome-wide fashion, dissociating mutation rate measurements from the traditional underlying assumptions.…

Genomics · Quantitative Biology 2015-05-14 D. Parkhomchuk , V. S. Amstislavskiy , A. Soldatov , V. Ogryzko

We introduce an algorithm to generate multivariate series of symbols from a finite alphabet with a given hierarchical structure of similarities. The target hierarchical structure of similarities is arbitrary, for instance the one obtained…

Computational Physics · Physics 2008-10-08 Mi. Tumminello , F. Lillo , R. N. Mantegna

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

Multi-omic datasets offer opportunities for improved biomarker discovery in cancer research, but their high dimensionality and limited sample sizes make identifying compact and effective biomarker panels challenging. Feature selection in…

Genomics · Quantitative Biology 2026-04-02 Luca Cattelani , Vittorio Fortino