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Microscope objectives achieve near diffraction-limited performance only when used under the conditions they are designed for. In non-standard geometries, such as thick cover slips or curved surfaces, severe aberrations arise, inevitably…

Optics · Physics 2025-03-24 D. W. S. Cox , T. Knop , I. M. Vellekoop

The usage of a GaAsP (gallium arsenide phosphide) photomultiplier for microscopical imaging allows the evaluation of low-light luminescent objects. We designed a setup for collecting a confocal microscopic image signal, which is divided…

Electron backscatter diffraction (EBSD) in the scanning electron microscope is routinely used for microstructural characterisation of polycrystalline materials. Maps of EBSD data are typically acquired at high stage tilt and slow scan…

Materials Science · Physics 2020-09-01 Vivian Tong , Thomas Benjamin Britton

Echo-planar imaging (EPI) remains the cornerstone of diffusion MRI, but it is prone to severe geometric distortions due to its rapid sampling scheme that renders the sequence highly sensitive to $B_{0}$ field inhomogeneities. While deep…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Namgyu Han , Seong Dae Yun , Chaeeun Lim , Sunghyun Seok , Sunju Kim , Yoonhwan Kim , Yohan Jun , Tae Hyung Kim , Berkin Bilgic , Jaejin Cho

Quality control in molecular optical sectioning microscopy is indispensable for transforming acquired digital images from qualitative descriptions to quantitative data. Although numerous tools, metrics, and phantoms have been developed,…

Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation or via clinical imaging systems, e.g., ultrasound or magnetic resonance imaging. Typically, the image based approaches are not suitable during…

Signal Processing · Electrical Eng. & Systems 2025-09-04 Maximilian Neidhardt , Sarah Latus , Tim Eixmann , Gereon Hüttmann , Alexander Schlaefer

When multimode optical fibers are perturbed, the data that is transmitted through them is scrambled. This presents a major difficulty for many possible applications, such as multimode fiber-based telecommunication and endoscopy. To overcome…

Image and Video Processing · Electrical Eng. & Systems 2022-02-17 Shachar Resisi , Sebastien M. Popoff , Yaron Bromberg

Video endoscopy represents a major advance in the investigation of gastrointestinal diseases. Reviewing endoscopy videos often involves frequent adjustments and reorientations to piece together a complete view, which can be both…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Juming Xiong , Muyang Li , Ruining Deng , Tianyuan Yao , Shunxing Bao , Regina N Tyree , Girish Hiremath , Yuankai Huo

Optical imaging through scattering media is an important challenge in a variety of fields ranging from microscopy to autonomous vehicles. While advanced wavefront shaping techniques have offered significant breakthroughs in the past decade,…

Optics · Physics 2023-05-23 Omri Haim , Jeremy Boger-Lombard , Ori Katz

Fluorescence microscopy is widely used in biological imaging, however scattering from tissues strongly limits its applicability to a shallow depth. In this work we adapt a methodology inspired from stellar speckle interferometry, and…

One challenge that has long held the attention of scientists is that of clearly seeing objects hidden by turbid media, as smoke, fog or biological tissue, which has major implications in fields such as remote sensing or early diagnosis of…

Optics · Physics 2014-11-12 V. Durán , F. Soldevila , E. Irles , P. Clemente , E. Tajahuerce , P. Andrés , J. Lancis

As recent advances in mobile camera technology have enabled the capability to capture high-resolution images, such as 4K images, the demand for an efficient deblurring model handling large motion has increased. In this paper, we discover…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Insoo Kim , Jae Seok Choi , Geonseok Seo , Kinam Kwon , Jinwoo Shin , Hyong-Euk Lee

Focusing waves inside inhomogeneous media is a fundamental problem for imaging. Spatial variations of wave velocity can strongly distort propagating wavefronts and degrade image quality. Adaptive focusing can compensate for such aberration,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 William Lambert , Laura A. Cobus , Thomas Frappart , Mathias Fink , Alexandre Aubry

Endoscopic surgery relies on intraoperative video, making image quality a decisive factor for surgical safety and efficacy. Yet, endoscopic videos are often degraded by uneven illumination, tissue scattering, occlusions, and motion blur,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Handing Xu , Zhenguo Nie , Tairan Peng , Huimin Pan , Xin-Jun Liu

Optical endomicroscopy (OEM) is an emerging technology platform with preclinical and clinical imaging applications. Pulmonary OEM via fibre bundles has the potential to provide in vivo, in situ molecular signatures of disease such as…

Computer Vision and Pattern Recognition · Computer Science 2018-08-29 Ahmed Karam Eldaly , Yoann Altmann , Antonios Perperidis , Nikola Krstajic , Tushar Choudhary , Kevin Dhaliwal , Stephen McLaughlin

Endoscopic image analysis is vital for colorectal cancer screening, yet real-world conditions often suffer from lens fogging, motion blur, and specular highlights, which severely compromise automated polyp detection. We propose EndoCaver, a…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhuoyu Wu , Wenhui Ou , Pei-Sze Tan , Jiayan Yang , Wenqi Fang , Zheng Wang , Raphaël C. -W. Phan

In recent years, the usefulness of 3D shape estimation is being realized in microscopic or close-range imaging, as the 3D information can further be used in various applications. Due to limited depth of field at such small distances, the…

Computer Vision and Pattern Recognition · Computer Science 2017-01-02 Arnav Bhavsar

Poor access to eye care is a major global challenge that could be ameliorated by low-cost, portable, and easy-to-use diagnostic technologies. Diffuser-based imaging has the potential to enable inexpensive, compact optical systems that can…

Medical Physics · Physics 2020-06-23 Yunzhe Li , Gregory N. McKay , Nicholas J. Durr , Lei Tian

We report a novel lensless on-chip microscopy platform based on near-field blind ptychographic modulation. In this platform, we place a thin diffuser in between the object and the image sensor for light wave modulation. By blindly scanning…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Shaowei Jiang , Jiakai Zhu , Pengming Song , Chengfei Guo , Zichao Bian , Ruihai Wang , Yikun Huang , Shiyao Wang , He Zhang , Guoan Zheng

Multimode fibers (MMFs) provide a compact, high-throughput platform for minimally invasive imaging and information transmission. However, their utility is fundamentally constrained by mode mixing, which renders image transmission spatially…

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