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Pandemics have the potential to cause immense disruption and damage to communities and societies. In this paper, we model the Influenza Pandemic of 2009. We propose a hybrid model to determine how the pandemic spreads through the world. The…

Populations and Evolution · Quantitative Biology 2010-06-02 Teruhiko Yoneyama , Mukkai S. Krishnamoorthy

The impact of information dissemination on epidemic control is essentially subject to individual behaviors. Unlike information-driven behaviors, vaccination is determined by many cost-related factors, whose correlation with the information…

Physics and Society · Physics 2019-04-03 Xiao-Jie Li , Cong Li , Xiang Li

The 1918 influenza pandemic was characterized by multiple epidemic waves. We investigated into reactive social distancing, a form of behavioral responses, and its effect on the multiple influenza waves in the United Kingdom. Two forms of…

Populations and Evolution · Quantitative Biology 2017-07-19 Duo Yu , Qianying Lin , Alice PY Chiu , Daihai He

Understanding how misinformation affects the spread of disease is crucial for public health, especially given recent research indicating that misinformation can increase vaccine hesitancy and discourage vaccine uptake. However, it is…

Social and Information Networks · Computer Science 2026-02-09 Matthew R. DeVerna , Francesco Pierri , Yong-Yeol Ahn , Santo Fortunato , Alessandro Flammini , Filippo Menczer

This paper presents several simple linear vaccination-based control strategies for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , S. Alonso-Quesada

Despite many studies on the transmission mechanism of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it remains still challenging to efficiently reduce mortality. In this work, we apply a two-population…

Physics and Society · Physics 2021-09-14 Long Ma , Maksim Kitsak , Piet Van Mieghem

Dengue remains a major global public health concern due to its high mortality and economic burden. Mathematical modeling is essential to understand its transmission mechanisms and for evaluating intervention strategies. In this paper, we…

Populations and Evolution · Quantitative Biology 2026-04-28 Sourav Banerjee , Thomas Götz , Satyananda Panda

With a simple phenomenological metapopulation model, which characterizes the invasion process of an influenza pandemic from a source to a subpopulation at risk, we compare the efficiency of inter- and intra-population interventions in…

Physics and Society · Physics 2012-09-27 Lin Wang , Yan Zhang , Tianyi Huang , Xiang Li

Background: Information on influenza-associated mortality in Russia is limited. Methods: Using previously developed methodology (Goldstein et al., Epidemiology 2012), we regressed the monthly rates of mortality for respiratory causes, as…

Populations and Evolution · Quantitative Biology 2019-12-02 Edward Goldstein

We introduce a new measure of antigenic distance between influenza A vaccine and circulating strains. The measure correlates well with efficacies of the H3N2 influenza A component of the annual vaccine between 1971 and 2004, as do results…

Biomolecules · Quantitative Biology 2007-05-23 Vishal Gupta , David J. Earl , Michael W. Deem

The Susceptible-Infected-Recovered (SIR) model has successfully mimicked the propagation of such airborne diseases as influenza A (H1N1). Although the SIR model has recently been studied in a multilayer networks configuration, in almost all…

Physics and Society · Physics 2015-07-16 L. G. Alvarez Zuzek , H. E. Stanley , L. A. Braunstein

We consider optimal vaccination protocol where the vaccine is in short supply. In this case, disease extinction results from a large and rare fluctuation. We show that the probability of such fluctuation can be exponentially increased by…

Populations and Evolution · Quantitative Biology 2013-05-29 M. Khasin , M. I. Dykman , B. Meerson

The accurate estimation of time-varying transmission rates is fundamental for understanding infectious disease dynamics and implementing effective public health interventions. To this end, we propose an improved inverse method for…

Populations and Evolution · Quantitative Biology 2025-12-17 Shuanglin Jing , Yuting Huang , Hai-Feng Huo

Decline of immunity is a phenomenon characterized by immunocompromised host and plays a crucial role in the epidemiology of emerging infectious diseases (EIDs) such as COVID-19. In this paper, we propose an age-structured model with…

Dynamical Systems · Mathematics 2024-07-23 Shuanglin Jing , Ling Xue , Jichen Yang

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

We use analytical methods to investigate a continuous vaccination strategy effects on the infectious disease dynamics in a closed population and a demographically open population. The methodology and key assumptions are based on Breda et al…

Populations and Evolution · Quantitative Biology 2020-09-24 Aubain Nzokem , Neal Madras

The Influenza A virus belongs to the Orthomyxoviridae family. Influenza virus infection occurs yearly in all countries of the world. It usually kills between 250,000 and 500,000 people and causes severe illness in millions more. Over the…

Cell Behavior · Quantitative Biology 2014-11-25 Juliana Silva Capitanio , Richard W. Wozniak

There is great interest in the dynamics of health behaviors in social networks and how they affect collective public health outcomes, but measuring population health behaviors over time and space requires substantial resources. Here, we use…

Social and Information Networks · Computer Science 2015-05-28 Marcel Salathé , Shashank Khandelwal

Public health surveillance systems often fail to detect emerging infectious diseases, particularly in resource limited settings. By integrating relevant clinical and internet-source data, we can close critical gaps in coverage and…

Applications · Statistics 2019-03-05 Kai Liu , Ravi Srinivasan , Lauren Ancel Meyers

Background: Network-based interventions are most powerful against epidemics when the full network structure is known. However, resource constraints often require decisions based on partial network data. We investigated how the effectiveness…

Populations and Evolution · Quantitative Biology 2018-03-30 Yingrui Yang , Ashley McKhann , Guy Harling , Jukka-Pekka Onnela