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Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Diffusion tensor imaging (DTI) plays a key role in analyzing the physical structures of biological tissues, particularly in reconstructing fiber tracts of the human brain in vivo. On the one hand, eigenvalues of diffusion tensors (DTs)…

Applications · Statistics 2013-04-18 Tao Yu , Chunming Zhang , Andrew L. Alexander , Richard J. Davidson

We enable the estimation of the per-axon axial diffusivity from single encoding, strongly diffusion-weighted, pulsed gradient spin echo data. Additionally, we improve the estimation of the per-axon radial diffusivity compared to estimates…

Medical Physics · Physics 2022-07-07 Marco Pizzolato , Erick Jorge Canales-Rodríguez , Mariam Andersson , Tim B. Dyrby

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

This paper presents an annotated dataset of brain MRI images designed to advance the field of brain symmetry study. Magnetic resonance imaging (MRI) has gained interest in analyzing brain symmetry in neonatal infants, and challenges remain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Arnaud Gucciardi , Safouane El Ghazouali , Francesca Venturini , Vida Groznik , Umberto Michelucci

We present a method for estimating intravoxel parameters from a DW-MRI based on deep learning techniques. We show that neural networks (DNNs) have the potential to extract information from diffusion-weighted signals to reconstruct cerebral…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Hanna Ehrlich , Mariano Rivera

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

Plane wave imaging (PWI) in medical ultrasound is becoming an important reconstruction method with high frame rates and new clinical applications. Recently, single PWI based on deep learning (DL) has been studied to overcome lowered frame…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hyunwoo Cho , Seongjun Park , Jinbum Kang , Yangmo Yoo

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Medical brain image analysis is a necessary step in Computer Assisted /Aided Diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 Darwin Castillo , Vasudevan Lakshminarayanan , Maria J. Rodriguez-Alvarez

Diffusion Magnetic Resonance Imaging (dMRI) is a non-invasive tool for watching the microstructure of fibrous nerve and muscle tissue. From dMRI, it is possible to estimate 2-rank diffusion tensors imaging (DTI) fields, that are widely used…

Computer Vision and Pattern Recognition · Computer Science 2016-06-28 Hernan Dario Vargas Cardona , Mauricio A. Alvarez , Alvaro A. Orozco

Recent research in neuroimaging has focused on assessing associations between genetic variants that are measured on a genomewide scale and brain imaging phenotypes. A large number of works in the area apply massively univariate analyses on…

Diffusion-weighted MRI (DW-MRI) is used to quantitatively characterize the microscopic structure of soft tissue due to the anisotropic diffusion of water in muscle. Applications such as fiber tractography or modeling of tumor spread in soft…

Medical Physics · Physics 2024-06-07 Nadya Shusharina , Xiaofeng Liu , Evangelia Kaza , Miranda Lam , Stephan Maier , Jonghye Woo

Diffusion Magnetic Resonance Imaging (dMRI) plays a critical role in studying microstructural changes in the brain. It is, therefore, widely used in clinical practice; yet progress in learning general-purpose representations from dMRI has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Gustavo Chau Loo Kung , Mohammad Abbasi , Camila Blank , Juze Zhang , Alan Q. Wang , Sophie Ostmeier , Akshay Chaudhari , Kilian Pohl , Ehsan Adeli

Accurately modeling longitudinal brain MRI progression is crucial for understanding neurodegenerative diseases and predicting individualized structural changes. Existing state-of-the-art approaches, such as Brain Latent Progression (BrLP),…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Cheng Wan , Bahram Jafrasteh , Ehsan Adeli , Miaomiao Zhang , Qingyu Zhao

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Ashiqur Rahman , Muhammad E. H. Chowdhury , Md Sharjis Ibne Wadud , Rusab Sarmun , Adam Mushtak , Sohaib Bassam Zoghoul , Israa Al-Hashimi

Stroke is a leading cause of mortality and disability. Emergent diagnosis and intervention are critical, and predicated upon initial brain imaging; however, existing clinical imaging modalities are generally costly, immobile, and demand…

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