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People's transportation choices reflect complex trade-offs shaped by personal preferences, social norms, and technology acceptance. Predicting such behavior at scale is a critical challenge with major implications for urban planning and…

Human-Computer Interaction · Computer Science 2026-01-28 Simon Lämmer , Mark Colley , Patrick Ebel

Fully Test-Time Adaptation (TTA), which aims at adapting models to data drifts, has recently attracted wide interest. Numerous tricks and techniques have been proposed to ensure robust learning on arbitrary streams of unlabeled data.…

Machine Learning · Computer Science 2023-11-13 Saypraseuth Mounsaveng , Florent Chiaroni , Malik Boudiaf , Marco Pedersoli , Ismail Ben Ayed

From scientific experiments to online A/B testing, the previously observed data often affects how future experiments are performed, which in turn affects which data will be collected. Such adaptivity introduces complex correlations between…

Machine Learning · Statistics 2018-01-03 Xinkun Nie , Xiaoying Tian , Jonathan Taylor , James Zou

Randomized Controlled Trials (RCTs) are the gold standard for evaluating the effect of new medical treatments. Treatments must pass stringent regulatory conditions in order to be approved for widespread use, yet even after the regulatory…

Machine Learning · Statistics 2025-03-13 Omer Noy Klein , Alihan Hüyük , Ron Shamir , Uri Shalit , Mihaela van der Schaar

Most clinical trials involve the comparison of a new treatment to a control arm (e.g., the standard of care) and the estimation of a treatment effect. External data, including historical clinical trial data and real-world observational…

Methodology · Statistics 2021-03-17 Tianjian Zhou , Yuan Ji

Graph contrastive learning (GCL) has become a hot topic in the field of graph representation learning. In contrast to traditional supervised learning relying on a large number of labels, GCL exploits augmentation strategies to generate…

Machine Learning · Computer Science 2025-03-28 Jianqing Liang , Xinkai Wei , Min Chen , Zhiqiang Wang , Jiye Liang

Response-adaptive designs have been extensively studied and used in clinical trials. However, there is a lack of a comprehensive study of response-adaptive designs that include covariates, despite their importance in clinical experiments.…

Statistics Theory · Mathematics 2008-12-26 Li-Xin Zhang , Feifang Hu , Siu Hung Cheung , Wai Sum Chan

In learning-phase clinical trials in drug development, adaptive designs can be efficient and highly informative when used appropriately. In this article, we extend the multiple comparison procedures with modeling techniques (MCP-Mod)…

Methodology · Statistics 2021-08-02 Shiyang Ma , Michael P. McDermott

As clinical decision-making increasingly moves toward individualized and context-specific treatment recommendations, reliance on any single evidence source, randomized or observational, may be insufficient. Principled integration of…

Generalizability and transportability methods have been proposed to address the external validity bias of randomized clinical trials that results from differences in the distribution of treatment effect modifiers between trial and target…

In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency with the final hypothesis testing decision. Accordingly, as…

Effective decision making from randomised controlled clinical trials relies on robust interpretation of the numerical results. However, the language we use to describe clinical trials can cause confusion both in trial design and in…

Continual Test-Time Adaptation (CTA) is a challenging task that aims to adapt a source pre-trained model to continually changing target domains. In the CTA setting, a model does not know when the target domain changes, thus facing a drastic…

Machine Learning · Computer Science 2024-03-05 Inseop Chung , Kyomin Hwang , Jayeon Yoo , Nojun Kwak

Background: Advanced adaptive randomised clinical trials are increasingly used. Compared to their conventional counterparts, their flexibility may make them more efficient, increase the probability of obtaining conclusive results without…

We consider a general difference-in-differences model in which the treatment variable of interest may be non-binary and its value may change in each period. It is generally difficult to estimate treatment parameters defined with the…

Econometrics · Economics 2023-05-30 Takahide Yanagi

Individualized randomized experiments are central to online platforms for optimizing personalized decisions in complex environments. In two-sided markets, however, standard treatment effect estimation is often invalid due to strong temporal…

Methodology · Statistics 2026-05-27 Shuguang Yu , Ting Li , Yuchen Lu , Chengchun Shi , Fan Zhou , Zhichao Zou , Peng Zhen , Hongtu Zhu

Since distribution shifts are likely to occur during test-time and can drastically decrease the model's performance, online test-time adaptation (TTA) continues to update the model after deployment, leveraging the current test data.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Robert A. Marsden , Mario Döbler , Bin Yang

One of the fastest evolving field among teaching and learning research is students' performance evaluation. Computer based testing systems are increasingly adopted by universities. However, the implementation and maintenance of such a…

Computers and Society · Computer Science 2016-08-14 Margit Antal , Levente Erős , Attila Imre

Test-time adaptation (TTA) intends to adapt the pretrained model to test distributions with only unlabeled test data streams. Most of the previous TTA methods have achieved great success on simple test data streams such as independently…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Longhui Yuan , Binhui Xie , Shuang Li

Methods for extending -- generalizing or transporting -- inferences from a randomized trial to a target population involve conditioning on a large set of covariates that is sufficient for rendering the randomized and non-randomized groups…