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A stochastic model for the growth of a virus in a cell population is introduced. The virus has two ways of spreading: either by allowing its host cell to live on and duplicate, or else by multiplying in large numbers within the host cell…

Cell Behavior · Quantitative Biology 2012-10-30 Jakob E. Björnberg , Tom Britton , Erik I. Broman , Eviatar Natan

We consider a branching particle system where each particle moves as an independent Brownian motion and breeds at a rate proportional to its distance from the origin raised to the power $p$, for $p\in[0,2)$. The asymptotic behaviour of the…

Probability · Mathematics 2014-02-24 Julien Berestycki , Éric Brunet , John W. Harris , Simon C. Harris , Matthew I. Roberts

Information transmission via communication between agents is ubiquitous on Earth, and is a vital facet of living systems. In this paper, we aim to quantify this rate of information transmission associated with Earth's biosphere and…

Physics and Society · Physics 2023-09-19 Manasvi Lingam , Adam Frank , Amedeo Balbi

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Fluctuations of cell state, e.g., abundances of some proteins, have attracted much attention both theoretically and experimentally. The distribution of such state over cells, however, is not only a result of intracellular stochastic…

Biological Physics · Physics 2007-05-23 Katsuhiko Sato , Kunihiko Kaneko

The adaptive immune system relies on the diversity of receptors expressed on the surface of B and T-cells to protect the organism from a vast amount of pathogenic threats. The proliferation and degradation dynamics of different cell types…

Populations and Evolution · Quantitative Biology 2016-02-10 Jonathan Desponds , Thierry Mora , Aleksandra M. Walczak

How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a…

Consider a decision maker who is responsible to dynamically collect observations so as to enhance his information about an underlying phenomena of interest in a speedy manner while accounting for the penalty of wrong declaration. Due to the…

Information Theory · Computer Science 2013-12-19 Mohammad Naghshvar , Tara Javidi

Energy efficient information transmission may be relevant to biological sensory signal processing as well as to low power electronic devices. We explore its consequences in two different regimes. In an ``immediate'' regime, we argue that…

Statistical Mechanics · Physics 2007-05-23 Vijay Balasubramanian , Don Kimber , Michael J Berry

Intelligent behavior in life-like systems often arises from the ability to gather, process, and act on information. While active matter provides a framework for studying life-like dynamics, it typically omits internal information-processing…

Statistical Mechanics · Physics 2026-03-02 Kristian Stølevik Olsen , Mitsusuke Tarama , Hartmut Löwen

We study the evolutionary dynamics of a phenotypically structured population in a changing environment , where the environmental conditions vary with a linear trend but in an oscillatory manner. Such phenomena can be described by parabolic…

Analysis of PDEs · Mathematics 2021-05-04 Susely Figueroa Iglesias , Sepideh Mirrahimi

Quantitative assessment of the growth of biological organisms has produced many mathematical equations. Many efforts have been given on statistical identification of the correct growth model from experimental data. Every growth equation is…

Methodology · Statistics 2021-02-17 Md Aktar Ul Karim , Supriya Ramdas Bhagat , Amiya Ranjan Bhowmick

In varying environments it is beneficial for organisms to utilize available cues to infer the conditions they may encounter and express potentially favorable traits. However, external cues can be unreliable or too costly to use. We consider…

Populations and Evolution · Quantitative Biology 2023-01-10 Leo Law , BingKan Xue

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

A recurrent idea in the study of complex systems is that optimal information processing is to be found near bifurcation points or phase transitions. However, this heuristic hypothesis has few (if any) concrete realizations where a standard…

Neurons and Cognition · Quantitative Biology 2007-05-23 Osame Kinouchi , Mauro Copelli

Isogenic Escherichia coli growing exponentially in a constant environment display large variation in growth-rates, division-sizes and generation-times. It is unclear how these seemingly random cell cycles can be reconciled with the precise…

Quantitative Methods · Quantitative Biology 2015-10-14 Mats Wallden , David Fange , Özden Baltekin , Johan Elf

Biomolecules stochastically occupy different possible configurations with probabilities given by non-equilibrium steady-state distributions. These distributions are determined by the transition rate constants between different…

Biological Physics · Physics 2024-07-19 Easun Arunachalam , Milo M. Lin

Organisms must acquire and use environmental information to guide their behaviors. However, it is unclear whether and how information quantitatively limits behavioral performance. Here, we relate information to behavioral performance in…

Biological Physics · Physics 2023-02-22 Henry H. Mattingly , Keita Kamino , Benjamin B. Machta , Thierry Emonet

Recently, the impacts of spatiotemporal heterogeneities of human activities on spreading dynamics have attracted extensive attention. In this paper, to study heterogeneous response times on information spreading, we focus on the…

Physics and Society · Physics 2015-06-18 Ai-Xiang Cui , Wei Wang , Ming Tang , Yan Fu , Xiaoming Liang , Younghae Do

Single-cell experiments have revealed cell-to-cell variability in generation times and growth rates for genetically identical cells. Theoretical models relating the fluctuating generation times of single cells to the population growth rate…

Populations and Evolution · Quantitative Biology 2020-01-15 Jie Lin , Ariel Amir
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