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We introduce a method that automatically and jointly updates both continuous and discrete parameters of a compound lens design, to improve its performance in terms of sharpness, speed, or both. Previous methods for compound lens design use…

Graphics · Computer Science 2025-09-30 Arjun Teh , Delio Vicini , Bernd Bickel , Ioannis Gkioulekas , Matthew O'Toole

Collective guidance of out-of-equilibrium systems without using external fields is a challenge of paramount importance in active matter, ranging from bacterial colonies to swarms of self-propelled particles. Designing strategies to guide…

In order to optimize a self-assembly reaction, it is essential to understand the factors that govern its pathway. Here, we examine the influence of nucleation pathways in a model system for addressable, multicomponent self-assembly based on…

Soft Condensed Matter · Physics 2018-08-01 Martin Sajfutdinow , William M. Jacobs , Aleks Reinhardt , Christoph Schneider , David M. Smith

The ability to control forces between sub-micron-scale building blocks offers considerable potential for designing new materials through self-assembly. A typical paradigm is to first identify a particular (crystal) structure that has some…

Soft Condensed Matter · Physics 2024-04-24 Mengjie Zu , Carl Goodrich

We describe a computational model for studying the complexity of self-assembled structures with active molecular components. Our model captures notions of growth and movement ubiquitous in biological systems. The model is inspired by…

Data Structures and Algorithms · Computer Science 2013-01-15 Damien Woods , Ho-Lin Chen , Scott Goodfriend , Nadine Dabby , Erik Winfree , Peng Yin

We numerically investigate local defectiveness control of self-assembled diblock copolymer patterns through appropriate substrate design. We use a nonlocal Cahn-Hilliard (CH) equation for the phase separation dynamics of diblock copolymers.…

Soft Condensed Matter · Physics 2017-02-13 D. Jeong , Y. Choi , J. Kim

In the present paper, an integrated paradigm for topology optimization on complex surfaces with arbitrary genus is proposed. The approach is constructed based on the two-dimensional (2D) Moving Morphable Component (MMC) framework, where a…

Optimization and Control · Mathematics 2022-02-03 Wendong Huo , Chang Liu , Zongliang Du , Xudong Jiang , Zhengyu Liu , Xu Guo

The main focus of the present work is the inclusion of spatial adaptivity for the snapshot computation in the offline phase of model order reduction utilizing Proper Orthogonal Decomposition (POD-MOR) for nonlinear parabolic evolution…

Numerical Analysis · Mathematics 2020-08-04 Carmen Gräßle , Michael Hinze

This paper investigates a Cahn-Hilliard-Swift-Hohenberg system, focusing on a three-species chemical mixture subject to physical constraints on volume fractions. The resulting system leads to complex patterns involving a separation into…

Analysis of PDEs · Mathematics 2024-10-02 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Andrea Signori

The design space for a self-assembled multicomponent objects ranges from a solution in which every building block is unique to one with the minimum number of distinct building blocks that unambiguously define the target structure. Using a…

Soft Condensed Matter · Physics 2023-03-13 Joakim Bohlin , Andrew J. Turberfield , Ard A. Louis , Petr Šulc

The problem of organizing data that evolves over time into clusters is encountered in a number of practical settings. We introduce evolutionary subspace clustering, a method whose objective is to cluster a collection of evolving data points…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Abolfazl Hashemi , Haris Vikalo

We study two fully discrete evolving surface finite element schemes for the Cahn-Hilliard equation on an evolving surface, given a smooth potential with polynomial growth. In particular we establish optimal order error bounds for a (fully…

Numerical Analysis · Mathematics 2025-03-14 Charles M. Elliott , Thomas Sales

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical…

Machine Learning · Computer Science 2025-09-08 Matouš Soldát , Jiří Kléma

In this paper we present a mixed projection- and density-based topology optimization approach. The aim is to combine the benefits of both parametrizations: the explicit geometric representation provides specific controls on certain design…

Computational Engineering, Finance, and Science · Computer Science 2019-10-09 Nicolò Pollini , Oded Amir

Self-closing assembly is prone to polymorphism due to thermally-excited bending fluctuations, which permit the formation of off-target assemblies at the point of self-closure. One way to overcome this source of polymorphism is to use…

Soft Condensed Matter · Physics 2025-11-06 Sirui Liu , Thomas E. Videbæk , W. Benjamin Rogers

Molecular computing promises massive parallelization to explore solution spaces, but so far practical implementations remain limited due to off-target binding and exponential proliferation of competing structures. Here, we investigate the…

Soft Condensed Matter · Physics 2025-09-26 Erin Crawley , Qian-Ze Zhu , Michael P. Brenner

We formulate statistical-mechanical inverse methods in order to determine optimized interparticle interactions that spontaneously produce target many-particle configurations. Motivated by advances that give experimentalists greater and…

Soft Condensed Matter · Physics 2007-05-23 Mikael C. Rechtsman , Salvatore Torquato , Frank H. Stillinger

Two meta-evolutionary optimization strategies described in this paper accelerate the convergence of evolutionary programming algorithms while still retaining much of their ability to deal with multi-modal problems. The strategies, called…

Neural and Evolutionary Computing · Computer Science 2009-03-26 Ted Dunning

The generation of nanoscale square and stripe patterns is of major technological importance since they are compatible with industry-standard electronic circuitry. Recently, a blend of diblock copolymer interacting via hydrogen-bonding was…

Soft Condensed Matter · Physics 2009-11-13 Carlos I. Mendoza , Erasmo Batta

The self-assembly of anisotropic building blocks into complex spatial architectures is an important design strategy in material science but the mechanisms by which the anisotropic interactions influence the early-stage growth and formation…

Soft Condensed Matter · Physics 2026-05-05 Dillip Kumar Mohapatra , Teun W. J. Verouden , Janne-Mieke Meijer