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Simulating soft matter systems such as the cytoskeleton can enable deep understanding of experimentally observed phenomena. One challenge of modeling such systems is realistic description of the steric repulsion between nearby polymers.…

Soft Condensed Matter · Physics 2021-12-22 Carlos Floyd , Aravind Chandrasekaran , Haoran Ni , Qin Ni , Garegin A. Papoian

The possibility of simulating in detail in-vivo experiments could be highly beneficial to the neuroscientific community. It could easily allow for preliminary testing of different experimental conditions without having to be constrained by…

Neurons and Cognition · Quantitative Biology 2020-04-10 Lorenzo Vannucci , Maria Pasquini , Cristina Spalletti , Matteo Caleo , Silvestro Micera , Cecilia Laschi , Egidio Falotico

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

Neural networks modularity is a major challenge for the development of control circuits of neural activity. Under physiological limitations, the accessible regions for external stimulation are possibly different from the functionally…

Neurons and Cognition · Quantitative Biology 2018-02-23 Hanna Keren , Johannes Partzsch , Shimon Marom , Christian Mayr

Tendon-driven robotic catheters are capable of precise execution of minimally invasive cardiac procedures including ablations and imaging. These procedures require accurate mathematical models of not only the catheter and tendons but also…

Robotics · Computer Science 2024-09-26 Pierre-Frédéric Villard , Thomas M. Waite , Robert D. Howe

Neural networks are a central technique in machine learning. Recent years have seen a wave of interest in applying neural networks to physical systems for which the governing dynamics are known and expressed through differential equations.…

Computational Physics · Physics 2020-01-31 M. Mattheakis , P. Protopapas , D. Sondak , M. Di Giovanni , E. Kaxiras

Despite advances in deep learning, robustness under domain shift remains a major bottleneck in medical imaging settings. Findings on natural images suggest that deep neural models can show a strong textural bias when carrying out image…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Seoin Chai , Daniel Rueckert , Ahmed E. Fetit

As deep neural networks grow in size, from thousands to millions to billions of weights, the performance of those networks becomes limited by our ability to accurately train them. A common naive question arises: if we have a system with…

Machine Learning · Computer Science 2018-05-29 Nathan O. Hodas , Panos Stinis

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

Musculoskeletal models have been widely used for detailed biomechanical analysis to characterise various functional impairments given their ability to estimate movement variables (i.e., muscle forces and joint moment) which cannot be…

Signal Processing · Electrical Eng. & Systems 2022-07-05 Jie Zhang , Yihui Zhao , Fergus Shone , Zhenhong Li , Alejandro F. Frangi , Shengquan Xie , Zhiqiang Zhang

It has been suggested that microtubules and other cytoskeletal filaments may act as electrical transmission lines. An electrical circuit model of the microtubule is constructed incorporating features of its cylindrical structure with…

Subcellular Processes · Quantitative Biology 2010-06-28 Holly Freedman , Vahid Rezania , Avner Priel , Eric Carpenter , Sergei Y. Noskovd , Jack A. Tuszynski

Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this…

Neurons and Cognition · Quantitative Biology 2018-11-01 David G. T. Barrett , Ari S. Morcos , Jakob H. Macke

We present a library to automatically embed signal processing and neural network predictions into the material robots are made of. Deep and shallow neural network models are first trained offline using state-of-the-art machine learning…

Robotics · Computer Science 2019-11-12 Sarah Aguasvivas Manzano , Dana Hughes , Cooper Simpson , Radhen Patel , Nikolaus Correll

We use a numerical electromagnetic simulation software to investigate a filtering device consisting of a small dimensional microstrips embedded with a thin layer of ferromagnetic material and we compare our results to experimental results.…

Materials Science · Physics 2008-02-20 Jonah N. Gollub , Bijoy Kuanr , Zibigniew Celinski , Robert Camley , David R. Smith

The dynamic of thermosensitive neuronal networks under the influence of external electric fields is explored, focusing on hybrid coupling models that incorporate both electrical and chemical synapses. Numerical simulations reveal a variety…

Chaotic Dynamics · Physics 2025-09-19 Ediline L. F. Nguessap , Antonio C. Roque , Fernando F. Ferreira

Artificial synapse is a key element of future brain-inspired neuromorphic computing systems implemented in hardware. This work presents a graphene synaptic transistor based on all-technology-compatible materials that exhibits highly tunable…

A network of semiflexible biopolymers, known as the cytoskeleton, and molecular motors play fundamental mechanical roles in cellular activities. The cytoskeletal response to forces generated by molecular motors is profoundly linked to…

Soft Condensed Matter · Physics 2022-05-25 N. Honda , K. Shiraki , F. van Esterik , S. Inokuchi , H. Ebata , D. Mizuno

Design of robots at the small scale is a trial-and-error based process, which is costly and time-consuming. There are few dynamic simulation tools available to accurately predict the motion or performance of untethered microrobots as they…

Robotics · Computer Science 2020-10-08 Jiayin Xie , Chenghao Bi , David J. Cappelleri , Nilanjan Chakraborty

Translating neural networks from theory to clinical practice has unique challenges, specifically in the field of neuroimaging. In this paper, we present DeepNeuro, a deep learning framework that is best-suited to putting deep learning…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Andrew Beers , James Brown , Ken Chang , Katharina Hoebel , Elizabeth Gerstner , Bruce Rosen , Jayashree Kalpathy-Cramer

Entangled networks of stiff biopolymers exhibit complex dynamic response, emerging from the topological constraints that neighboring filaments impose upon each other. We propose a class of reference models for entanglement dynamics of stiff…

Soft Condensed Matter · Physics 2008-06-23 Felix Höfling , Tobias Munk , Erwin Frey , Thomas Franosch
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