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Drug development is time-consuming and expensive. Repurposing existing drugs for new therapies is an attractive solution that accelerates drug development at reduced experimental costs, specifically for Coronavirus Disease 2019 (COVID-19),…

Biomolecules · Quantitative Biology 2022-02-11 Xiaoqin Pan , Xuan Lin , Dongsheng Cao , Xiangxiang Zeng , Philip S. Yu , Lifang He , Ruth Nussinov , Feixiong Cheng

Service Oriented Architecture is a loosely coupled architecture designed to tackle the problem of Business Infrastructure alignment to meet the needs of an organization. A SOA based platform enables the enterprises to develop applications…

Software Engineering · Computer Science 2014-11-26 Debajyoti Mukhopadhyay , Juhi Jariwala , Payal Innani , Sheetal Bablani , Sushama Kothawale

The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

Physics and Society · Physics 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

Introduction: Artificial intelligence (AI) is exhibiting tremendous potential to reduce the massive costs and long timescales of drug discovery. There are however important challenges currently limiting the impact and scope of AI models.…

Other Quantitative Biology · Quantitative Biology 2024-09-25 Ghita Ghislat , Saiveth Hernandez-Hernandez , Chayanit Piyawajanusorn , Pedro J. Ballester

With the advance of Web Services technologies and the emergence of Web Services into the information space, tremendous opportunities for empowering users and organizations appear in various application domains including electronic commerce,…

Databases · Computer Science 2011-03-07 Hela Limam , Jalel Akaichi

The current zero trust model adopted in System-on-Chip (SoC) design is vulnerable to various malicious entities, and modern SoC designs must incorporate various security policies to protect sensitive assets from unauthorized access. These…

Cryptography and Security · Computer Science 2023-08-08 Sudipta Paria , Swarup Bhunia

Because Service-Oriented Architecture (SOA) is one of the hottest topics that is currently gaining momentum, and the number of its adopters (both business and IT executives) is increasing in a tremendous manner, it is really a must to…

Software Engineering · Computer Science 2012-03-01 Qusay F. Hassan

In this paper based on agent and semantic web technologies we propose an approach .i.e., Semantic Oriented Agent Based Search (SOAS), to cope with currently existing challenges of Meta data extraction, modeling and information retrieval…

Information Retrieval · Computer Science 2010-08-10 Zeeshan Ahmed , Detlef Gerhard

Bringing together the information latent in distributed medical databases promises to personalize medical care by enabling reliable, stable modeling of outcomes with rich feature sets (including patient characteristics and treatments…

Access to healthcare facilities is a critical issue in developing countries, where limited resources and significant challenges hinder progress toward universal health coverage, one of the targets pursued by the United Nations. As a result,…

Optimization and Control · Mathematics 2026-03-24 Laura Davila-Pena , Maria Paola Scaparra , Dick den Hertog

Due to their excellent drug-like and pharmacokinetic properties, small molecule drugs are widely used to treat various diseases, making them a critical component of drug discovery. In recent years, with the rapid development of deep…

Machine Learning · Computer Science 2025-05-15 Kun Li , Yida Xiong , Hongzhi Zhang , Xiantao Cai , Jia Wu , Bo Du , Wenbin Hu

Implementing Information and Communication Technology (ICT) solutions can alleviate pressing problems in society and are a central component of sustainable development. Often, healthcare addresses the symptoms without approaching the…

Computers and Society · Computer Science 2021-08-24 Martina A. Clarke , Sajda Qureshi , Timi Barone , John R. Windle

Drug repurposing has historically been an economically infeasible process for identifying novel uses for abandoned drugs. Modern machine learning has enabled the identification of complex biochemical intricacies in candidate drugs; however,…

Machine Learning · Computer Science 2025-09-16 Luke Delzer , Robert Kroleski , Ali K. AlShami , Jugal Kalita

In this fast developing world of information, the amount of medical knowledge is rising at an exponential level. The UMLS (Unified Medical Language Systems), is rich knowledge base consisting files and software that provides many health and…

Computers and Society · Computer Science 2016-12-23 Nareena Soomro , Safeeulah Soomro , Zainab Alansari , Suhni Abbasi , Mohammad Riyaz Belgaum , Abdul Baqi Khakwani

Research papers in the biomedical field come with large and complex data sets that are shared with the scientific community as unstructured data files via public data repositories. Examples are sequencing, microarray, and mass spectroscopy…

Quantitative Methods · Quantitative Biology 2020-05-28 Michael Huttner , Claudio Lottaz , Christian Kohler , Rainer Spang

With the advancement in the technology sector spanning over every field, a huge influx of information is inevitable. Among all the opportunities that the advancements in the technology have brought, one of them is to propose efficient…

Information Retrieval · Computer Science 2021-12-14 Sudhanshu , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

Maintaining competitive advantage is significant in this present day of globalization, knowledge management and enormous economic activities. An organization's future developments are influenced by its managements' decisions. Businesses…

Other Computer Science · Computer Science 2013-07-31 Quist-Aphetsi Kester , Koumadi , Koudjo M , Nii Narku Quaynor

Regarding to the smart city infrastructures, there is a demand for big data processing and its further usage. This data can be gained by various means. There are many IoT devices in the city, which can communicate and share the information…

Computers and Society · Computer Science 2023-01-24 Zuzana Špitálová , Oliver Leontiev , Patrik Harmaňoš

Every year, millions of pounds of medicines remain unused in the U.S. and are subject to an in-home disposal, i.e., kept in medicine cabinets, flushed in toilet or thrown in regular trash. In-home disposal, however, can negatively impact…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Bahram Marami , Atabak Reza Royaee

Distributed applications are broadly used due the existence of mobile devices as are mobile phones, tablets and chrome books. They are often based on an architecture client-server. A server part contains a central storage where all…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-04-12 Jan Kožusznik
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