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Related papers: MSARC: Multiple Sequence Alignment by Residue Clus…

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Most machine learning classifiers only concern classification accuracy, while certain applications (such as medical diagnosis, meteorological forecasting, and computation advertising) require the model to predict the true probability, known…

Machine Learning · Computer Science 2025-03-13 Siguang Huang , Yunli Wang , Lili Mou , Huayue Zhang , Han Zhu , Chuan Yu , Bo Zheng

Many biological questions, including the estimation of deep evolutionary histories and the detection of remote homology between protein sequences, rely upon multiple sequence alignments (MSAs) and phylogenetic trees of large datasets.…

Genomics · Quantitative Biology 2015-04-07 Nam-phuong Nguyen , Siavash Mirarab , Keerthana Kumar , Tandy Warnow

This paper addresses the problem of fault diagnosis in multistation assembly systems. Fault diagnosis is to identify process faults that cause the excessive dimensional variation of the product using dimensional measurements. For such…

Applications · Statistics 2022-10-31 Jihoon Chung , Bo Shen , Zhenyu , Kong

Multi-view Clustering (MVC) has achieved significant progress, with many efforts dedicated to learn knowledge from multiple views. However, most existing methods are either not applicable or require additional steps for incomplete MVC. Such…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Junjie Liu , Junlong Liu , Rongxin Jiang , Yaowu Chen , Chen Shen , Jieping Ye

Sequences of nucleotides (for DNA and RNA) or amino acids (for proteins) are central objects in biology. Among the most important computational problems is that of sequence alignment, i.e. arranging sequences from different organisms in…

Quantitative Methods · Quantitative Biology 2020-12-08 Anna Paola Muntoni , Andrea Pagnani , Martin Weigt , Francesco Zamponi

In this paper we address the application of pre-processing techniques to multi-channel time series data with varying lengths, which we refer to as the alignment problem, for downstream machine learning. The misalignment of multi-channel…

Numerous machine learning (ML) models employed in protein function and structure prediction depend on evolutionary information, which is captured through multiple-sequence alignments (MSA) or position-specific scoring matrices (PSSM) as…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Issar Arab

Semi-supervised learning (SSL) is a promising machine learning paradigm to address the issue of label scarcity in medical imaging. SSL methods were originally developed in image classification. The state-of-the-art SSL methods in image…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Mou-Cheng Xu , Yukun Zhou , Chen Jin , Marius De Groot , Neil P. Oxtoby , Daniel C. Alexander , Joseph Jacob

The modern scale of data has brought new challenges to Bayesian inference. In particular, conventional MCMC algorithms are computationally very expensive for large data sets. A promising approach to solve this problem is embarrassingly…

Machine Learning · Statistics 2015-10-27 Xiangyu Wang , Fangjian Guo , Katherine A. Heller , David B. Dunson

We study the problem of aligning multiple sequences with the goal of finding an alignment that either maximizes the number of aligned symbols (the longest common subsequence (LCS)), or minimizes the number of unaligned symbols (the…

Data Structures and Algorithms · Computer Science 2021-10-26 Debarati Das , Barna Saha

Multiple sequence alignment (MSA) plays a key role in biological sequence analyses, especially in phylogenetic tree construction. Extreme increase in next-generation sequencing results in shortage of efficient ultra-large biological…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-05 Shixiang Wan , Quan Zou

Multi-Label Image Classification (MLIC) aims to predict a set of labels that present in an image. The key to deal with such problem is to mine the associations between image contents and labels, and further obtain the correct assignments…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Yanan Wu , He Liu , Songhe Feng , Yi Jin , Gengyu Lyu , Zizhang Wu

Multi-view clustering (MVC), which effectively fuses information from multiple views for better performance, has received increasing attention. Most existing MVC methods assume that multi-view data are fully paired, which means that the…

Machine Learning · Computer Science 2023-07-10 Yi Wen , Siwei Wang , Qing Liao , Weixuan Liang , Ke Liang , Xinhang Wan , Xinwang Liu

Due to the increased availability of large datasets of biological sequences, the tools for sequence comparison are now relying on efficient alignment-free approaches to a greater extent. Most of the alignment-free approaches require the…

Data Structures and Algorithms · Computer Science 2018-07-23 F. Garofalo , G. Rosone , M. Sciortino , D. Verzotto

Bayesian inference is now a leading technique for reconstructing phylogenetic trees from aligned sequence data. In this short note, we formally show that the maximum posterior tree topology provides a statistically consistent estimate of a…

Populations and Evolution · Quantitative Biology 2013-07-12 Mike Steel

Several structure-learning algorithms for staged trees, asymmetric extensions of Bayesian networks, have been proposed. However, these either do not scale efficiently as the number of variables considered increases, a priori restrict the…

Methodology · Statistics 2022-11-15 Peter Strong , Jim Q. Smith

We study how to allocate a fixed supervised fine-tuning budget when three objectives must be balanced at once: multi-turn safety alignment, low over-refusal on benign boundary queries, and instruction following under verifiable constraints.…

Cryptography and Security · Computer Science 2026-03-20 Yipu Dou , Wang Yang

With the development of multimedia systems, multimodal recommendations are playing an essential role, as they can leverage rich contexts beyond interactions. Existing methods mainly regard multimodal information as an auxiliary, using them…

Information Retrieval · Computer Science 2024-08-02 Yifan Liu , Kangning Zhang , Xiangyuan Ren , Yanhua Huang , Jiarui Jin , Yingjie Qin , Ruilong Su , Ruiwen Xu , Yong Yu , Weinan Zhang

Advances in bio-technology have made available massive amounts of functional, structural and genomic data for many biological sequences. This increased availability of heterogeneous biological data has resulted in biological applications…

Computational Engineering, Finance, and Science · Computer Science 2013-02-26 Srikrishnan Divakaran , Arpit Mithal , Namit Jain

Multimodal representation is faithful and highly effective in describing real-world data samples' characteristics by describing their complementary information. However, the collected data often exhibits incomplete and misaligned…

Machine Learning · Computer Science 2025-07-08 Shubin Ma , Liang Zhao , Mingdong Lu , Yifan Guo , Bo Xu