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Mutations of genetic sequences are often accompanied by their recombinations, known as phylogenetic networks. These networks are typically reconstructed from coalescent processes that may arise from optimal merging or fitting together a…

Algebraic Topology · Mathematics 2024-08-28 Paweł Dłotko , Jan Felix Senge , Anastasios Stefanou

Surface registration is a technique that is used in various areas such as object recognition and 3D model reconstruction. Problem of surface registration can be analyzed as an optimization problem of seeking a rigid motion between two…

Computer Vision and Pattern Recognition · Computer Science 2013-10-02 Vedran Hrgetić , Tomislav Pribanić

We address the problem of computing distances between rankings that take into account similarities between candidates. The need for evaluating such distances is governed by applications as diverse as rank aggregation, bioinformatics, social…

Data Structures and Algorithms · Computer Science 2014-11-20 Farzad Farnoud , Lili Su , Gregory J. Puleo , Olgica Milenkovic

Motivated by applications in single-cell biology and metagenomics, we investigate the problem of matrix reordering based on a noisy disordered monotone Toeplitz matrix model. We establish the fundamental statistical limit for this problem…

Statistics Theory · Mathematics 2023-08-15 T. Tony Cai , Rong Ma

The seriation problem seeks to reorder a set of elements given pairwise similarity information, so that elements with higher similarity are closer in the resulting sequence. When a global ordering consistent with the similarity information…

Optimization and Control · Mathematics 2018-06-05 Antoine Recanati , Nicolas Servant , Jean-Philippe Vert , Alexandre d'Aspremont

This paper is concerned with the problem of recovering an unknown matrix from a small fraction of its entries. This is known as the matrix completion problem, and comes up in a great number of applications, including the famous Netflix…

Information Theory · Computer Science 2009-03-10 Emmanuel J. Candes , Terence Tao

Solution and analysis of mathematical programming problems may be simplified when these problems are symmetric under appropriate linear transformations. In particular, a knowledge of the symmetries may help reduce the problem dimension, cut…

Optimization and Control · Mathematics 2020-10-13 A. V. Eremeev , A. S. Yurkov

We address the problem of filling missing entries in a kernel Gram matrix, given a related full Gram matrix. We attack this problem from the viewpoint of regression, assuming that the two kernel matrices can be considered as explanatory…

Quantitative Methods · Quantitative Biology 2011-11-10 Yoshihiro Yamanishi , Jean-Philippe Vert

The last decade brought a significant increase in the amount of data and a variety of new inference methods for reconstructing the detailed evolutionary history of various cancers. This brings the need of designing efficient procedures for…

Data Structures and Algorithms · Computer Science 2020-04-30 Giulia Bernardini , Paola Bonizzoni , Paweł Gawrychowski

We consider the following problem: from a given set of gene families trees on a set of genomes, find a first speciation, that splits these genomes into two subsets, that minimizes the number of gene duplications that happened before this…

Discrete Mathematics · Computer Science 2009-04-15 Cedric Chauve , Aïda Ouangraoua

Colorectal cancer is the third-most common cancer in the Western Hemisphere. The segmentation of colorectal and colorectal cancer by computed tomography is an urgent problem in medicine. Indeed, a system capable of solving this problem will…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 I. M. Chernenkiy , Y. A. Drach , S. R. Mustakimova , V. V. Kazantseva , N. A. Ushakov , S. K. Efetov , M. V. Feldsherov

The design of genome-scale constraint-based metabolic networks has steadily advanced, with an increasing number of successful cases achieving growth-coupled production, in which the biosynthesis of key metabolites is linked to cell growth.…

Molecular Networks · Quantitative Biology 2026-05-19 Yier Ma , Takeyuki Tamura

Deciphering cell type heterogeneity is crucial for systematically understanding tissue homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient approach estimating cell type abundances from a variety of…

Other Quantitative Biology · Quantitative Biology 2023-09-06 Lana X. Garmire , Yijun Li , Qianhui Huang , Chuan Xu , Sarah Teichmann , Naftali Kaminski , Matteo Pellegrini , Quan Nguyen , Andrew E. Teschendorff

This paper provides the best bounds to date on the number of randomly sampled entries required to reconstruct an unknown low rank matrix. These results improve on prior work by Candes and Recht, Candes and Tao, and Keshavan, Montanari, and…

Information Theory · Computer Science 2009-10-21 Benjamin Recht

We propose a novel Riemannian method for solving the Extreme multi-label classification problem that exploits the geometric structure of the sparse low-dimensional local embedding models. A constrained optimization problem is formulated as…

Optimization and Control · Mathematics 2021-10-01 Jayadev Naram , Tanmay Kumar Sinha , Pawan Kumar

With the constant advancements of genetic engineering, a common concern is to be able to identify the lab-of-origin of genetically engineered DNA sequences. For that reason, AltLabs has hosted the genetic Engineering Attribution Challenge…

Machine Learning · Computer Science 2021-07-19 I. Muniz , F. H. F. Camargo , A. Marques

In this paper, we present a new algorithm for computing the linear recurrence relations of multi-dimensional sequences. Existing algorithms for computing these relations arise in computational algebra and include constructing structured…

Symbolic Computation · Computer Science 2024-10-23 Hamid Rahkooy

We propose a machine learning based approach for automatic regularization and polygonization of building segmentation masks. Taking an image as input, we first predict building segmentation maps exploiting generic fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Stefano Zorzi , Ksenia Bittner , Friedrich Fraundorfer

We propose an extremely versatile approach to address a large family of matrix nearness problems, possibly with additional linear constraints. Our method is based on splitting a matrix nearness problem into two nested optimization problems,…

Numerical Analysis · Mathematics 2025-08-14 Miryam Gnazzo , Vanni Noferini , Lauri Nyman , Federico Poloni

Computing a consensus object from a set of given objects is a core problem in machine learning and pattern recognition. One popular approach is to formulate it as an optimization problem using the generalized median. Previous methods like…

Computer Vision and Pattern Recognition · Computer Science 2022-09-22 Andreas Nienkötter , Xiaoyi Jiang