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Redistricting is the problem of partitioning a set of geographical units into a fixed number of districts, subject to a list of often-vague rules and priorities. In recent years, the use of randomized methods to sample from the vast space…

Computers and Society · Computer Science 2019-11-14 Daryl DeFord , Moon Duchin , Justin Solomon

Recently, due to the genomic sequence analysis in several types of cancer, the genomic data based on {\em copy number profiles} ({\em CNP} for short) are getting more and more popular. A CNP is a vector where each component is a…

Data Structures and Algorithms · Computer Science 2020-02-13 Manuel Lafond , Binhai Zhu , Peng Zou

We consider optimization problems involving the multiplication of variable matrices to be selected from a given family, which might be a discrete set, a continuous set or a combination of both. Such nonlinear, and possibly discrete,…

Optimization and Control · Mathematics 2021-03-12 Burak Kocuk

An important application of distance geometry to biochemistry studies the embeddings of the vertices of a weighted graph in the three-dimensional Euclidean space such that the edge weights are equal to the Euclidean distances between…

Computational Geometry · Computer Science 2011-03-08 Leo Liberti , Carlile Lavor , Benoit Masson , Antonio Mucherino

In this paper, we define the geometric median of a probability measure on a Riemannian manifold, give its characterization and a natural condition to ensure its uniqueness. In order to calculate the median in practical cases, we also…

Differential Geometry · Mathematics 2019-02-20 Le Yang

De novo genome assembly focuses on finding connections between a vast amount of short sequences in order to reconstruct the original genome. The central problem of genome assembly could be described as finding a Hamiltonian path through a…

Machine Learning · Computer Science 2020-11-11 Lovro Vrček , Petar Veličković , Mile Šikić

Given a dissimilarity matrix, the metric nearness problem is to find the nearest matrix of distances that satisfy the triangle inequalities. This problem has wide applications, such as sensor networks, image processing, and so on. But it is…

Optimization and Control · Mathematics 2022-11-03 Peipei Tang , Bo Jiang , Chengjing Wang

Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions. While there are some more complex genome rearrangements such as…

Genomics · Quantitative Biology 2015-04-07 Nikita Alexeev , Rustem Aidagulov , Max A. Alekseyev

The problem of reconstructing evolutionary trees or phylogenies is of great interest in computational biology. A popular model for this problem assumes that we are given the set of leaves (current species) of an unknown binary tree and the…

Data Structures and Algorithms · Computer Science 2022-06-16 Eshwar Ram Arunachaleswaran , Anindya De , Sampath Kannan

In this work we study the interleaving distance between merge trees from a combinatorial point of view. We use a particular type of matching between trees to obtain a novel formulation of the distance. With such formulation, we tackle the…

Combinatorics · Mathematics 2024-11-11 Matteo Pegoraro

The classical branch-and-bound algorithm for the integer feasibility problem has exponential worst case complexity. We prove that it is surprisingly efficient on reformulated problems, in which the columns of the constraint matrix are…

Optimization and Control · Mathematics 2009-08-06 Gabor Pataki , Mustafa Tural

The article presents the theoretical foundations of the algorithm for calculating the number of different genomes in the medium under study and of two algorithms for determining the presence of a particular (known) genome in this medium.…

Genomics · Quantitative Biology 2015-06-23 Valery Kirzhner , Zeev Volkovich

Accelerated Cardiovascular Magnetic Resonance (CMR) image reconstruction remains a critical challenge due to the trade-off between scan time and image quality, particularly when generalizing across diverse acquisition settings. We propose…

Image and Video Processing · Electrical Eng. & Systems 2025-10-30 Kian Anvari Hamedani , Narges Razizadeh , Shahabedin Nabavi , Mohsen Ebrahimi Moghaddam

Given a matrix $A$, a linear feasibility problem (of which linear classification is a special case) aims to find a solution to a primal problem $w: A^Tw > \textbf{0}$ or a certificate for the dual problem which is a probability distribution…

Optimization and Control · Mathematics 2016-02-01 Aaditya Ramdas , Javier Peña

Previous divide-and-conquer segmentation analyses of DNA sequences do not provide a satisfactory stopping criterion for the recursion. This paper proposes that segmentation be considered as a model selection process. Using the tools in…

Biological Physics · Physics 2007-05-23 Wentian Li

The diagonalization of general mass matrices is a more delicate problem when eigenvalue degeneracies exist. In this case, often overlooked in the literature, some difficulties arise related to the freedom in the choice of basis in…

High Energy Physics - Phenomenology · Physics 2015-06-25 J. A. Aguilar-Saavedra

Finding the k-medianin a network involves identifying a subset of k vertices that minimize the total distance to all other vertices in a graph. This problem has been extensively studied in computer science, graph theory, operations…

Data Structures and Algorithms · Computer Science 2023-12-14 Roldan Pozo

The Single Cut or Join (SCJ) operation on genomes, generalizing chromosome evolution by fusions and fissions, is the computationally simplest known model of genome rearrangement. While most genome rearrangement problems are already hard…

Computational Engineering, Finance, and Science · Computer Science 2013-04-09 Istvan Miklos , Sandor Z. Kiss , Eric Tannier

We present subquadratic algorithms in the algebraic decision-tree model for several \textsc{3Sum}-hard geometric problems, all of which can be reduced to the following question: Given two sets $A$, $B$, each consisting of $n$ pairwise…

Computational Geometry · Computer Science 2021-09-17 Boris Aronov , Mark de Berg , Jean Cardinal , Esther Ezra , John Iacono , Micha Sharir

This article is the first part of a two-fold study, the objective of which is the theoretical analysis and numerical investigation of new approximate corrector problems in the context of stochastic homogenization. We present here three new…

Numerical Analysis · Mathematics 2018-07-16 Eric Cancès , Virginie Ehrlacher , Frederic Legoll , Benjamin Stamm , Shuyang Xiang
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