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In real life, it is always an urge to reach our goal in minimum effort i.e., it should have a minimum constrained path. The path may be shortest route in practical life, either physical or electronic medium. The scenario is to represents…

Neural and Evolutionary Computing · Computer Science 2014-01-14 Sounak Sadhukhan , Samar Sen Sarma

We study persistent query evaluation over streaming graphs, which is becoming increasingly important. We focus on navigational queries that determine if there exists a path between two entities that satisfies a user-specified constraint. We…

Databases · Computer Science 2020-04-07 Anil Pacaci , Angela Bonifati , M. Tamer Özsu

Single-cell RNA sequencing provides tremendous insights to understand biological systems. However, the noise from dropout can corrupt the downstream biological analysis. Hence, it is desirable to impute the dropouts accurately. In this…

Quantitative Methods · Quantitative Biology 2020-08-11 Kexin Huang

Graph Neural Networks (GNN) exhibit superior performance in graph representation learning, but their inference cost can be high, due to an aggregation operation that can require a memory fetch for a very large number of nodes. This…

Machine Learning · Computer Science 2025-03-18 Yaochen Hu , Mai Zeng , Ge Zhang , Pavel Rumiantsev , Liheng Ma , Yingxue Zhang , Mark Coates

Genome annotation is an important issue in biology which has long been addressed with gene prediction methods and manual experiments requiring biological expertise. The expanding Next Generation Sequencing technologies and their enhanced…

Computation · Statistics 2013-07-02 Alice Cleynen , Michel Koskas , Emilie Lebarbier , Guillem Rigaill , Stephane Robin

Ray tracing has become a standard for accurate radio propagation modeling, but suffers from exponential computational complexity, as the number of candidate paths scales with the number of objects raised to the interaction order. This…

Training on large-scale graphs has achieved remarkable results in graph representation learning, but its cost and storage have raised growing concerns. As one of the most promising directions, graph condensation methods address these issues…

Machine Learning · Computer Science 2024-09-30 Tianle Zhang , Yuchen Zhang , Kun Wang , Kai Wang , Beining Yang , Kaipeng Zhang , Wenqi Shao , Ping Liu , Joey Tianyi Zhou , Yang You

Unified graph representation learning aims to generate node embeddings, which can be applied to multiple downstream applications of graph analytics. However, existing studies based on graph neural networks and language models either suffer…

Computation and Language · Computer Science 2025-08-05 Wenbo Shang , Xuliang Zhu , Xin Huang

Aligning sequencing reads on graph representations of genomes is an important ingredient of pan-genomics. Such approaches typically find a set of local anchors that indicate plausible matches between substrings of a read to subpaths of the…

Data Structures and Algorithms · Computer Science 2018-01-30 Anna Kuosmanen , Topi Paavilainen , Travis Gagie , Rayan Chikhi , Alexandru I. Tomescu , Veli Mäkinen

In Bioinformatics, the applications of flow decomposition in directed acyclic graphs are highlighted in RNA Assembly problem. However, it admits multiple solutions where exactly one solution correctly represents the underlying transcripts.…

Data Structures and Algorithms · Computer Science 2024-09-23 Bashar Ahmed , Siddharth Singh Rana , Ujjwal , Shahbaz Khan

Regular path queries (RPQs) select nodes connected by some path in a graph. The edge labels of such a path have to form a word that matches a given regular expression. We investigate the evaluation of RPQs with an additional constraint that…

Databases · Computer Science 2013-01-01 Guillaume Bagan , Angela Bonifati , Benoit Groz

Graph comparison is a fundamental operation in data mining and information retrieval. Due to the combinatorial nature of graphs, it is hard to balance the expressiveness of the similarity measure and its scalability. Spectral analysis…

Social and Information Networks · Computer Science 2020-03-04 Anton Tsitsulin , Marina Munkhoeva , Bryan Perozzi

We introduce and study the complexity of Path Packing. Given a graph $G$ and a list of paths, the task is to embed the paths edge-disjoint in $G$. This generalizes the well known Hamiltonian-Path problem. Since Hamiltonian Path is…

Computational Complexity · Computer Science 2019-10-02 Jan Dreier , Janosch Fuchs , Tim A. Hartmann , Philipp Kuinke , Peter Rossmanith , Bjoern Tauer , Hung-Lung Wang

Analysis of single-cell RNA sequencing data is often conducted through network projections such as coexpression networks, primarily due to the abundant availability of network analysis tools for downstream tasks. However, this approach has…

Quantitative Methods · Quantitative Biology 2025-12-24 Wan He , Daniel I. Bolnick , Samuel V. Scarpino , Tina Eliassi-Rad

Recently Graph Neural Network (GNN) has been applied successfully to various NLP tasks that require reasoning, such as multi-hop machine reading comprehension. In this paper, we consider a novel case where reasoning is needed over graphs…

Computation and Language · Computer Science 2020-04-13 Ming Tu , Jing Huang , Xiaodong He , Bowen Zhou

The Smatch metric is a popular method for evaluating graph distances, as is necessary, for instance, to assess the performance of semantic graph parsing systems. However, we observe some issues in the metric that jeopardize meaningful…

Computation and Language · Computer Science 2025-10-17 Juri Opitz

Random walk neural networks (RWNNs) have emerged as a promising approach for graph representation learning, leveraging recent advances in sequence models to process random walks. However, under realistic sampling constraints, RWNNs often…

Machine Learning · Computer Science 2025-10-28 Michael Ito , Danai Koutra , Jenna Wiens

Isoform quantification is an important goal of RNA-seq experiments, yet it remains prob- lematic for genes with low expression or several isoforms. These difficulties may in principle be ameliorated by exploiting correlated experimental…

Genomics · Quantitative Biology 2016-02-23 Yuanhua Huang , Guido Sanguinetti

Graph neural networks (GNNs) have struggled to outperform traditional optimization methods on combinatorial problems, limiting their practical impact. We address this gap by introducing a novel chaining procedure for the graph alignment…

Machine Learning · Computer Science 2025-10-06 Marc Lelarge

In this paper we present an algorithmic framework for solving a class of combinatorial optimization problems on graphs with bounded pathwidth. The problems are NP-hard in general, but solvable in linear time on this type of graphs. The…

Data Structures and Algorithms · Computer Science 2012-12-18 Mugurel Ionut Andreica