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In this paper we propose a Monte Carlo maximum likelihood estimation strategy for discretely observed Wright-Fisher diffusions. Our approach provides an unbiased estimator of the likelihood function and is based on exact simulation…

Statistics Theory · Mathematics 2024-06-11 Celia García-Pareja , Fabio Nobile

We study voter models defined on large sets. Through a perspective emphasizing the martingale property of voter density processes, we prove that in general, their convergence to the Wright-Fisher diffusion only involves certain averages of…

Probability · Mathematics 2013-11-25 Yu-Ting Chen , Jihyeok Choi , J. Theodore Cox

Widely used models in genetics include the Wright-Fisher diffusion and its moment dual, Kingman's coalescent. Each has a multilocus extension but under neither extension is the sampling distribution available in closed-form, and their…

Probability · Mathematics 2015-06-24 Paul A. Jenkins , Paul Fearnhead , Yun S. Song

We study a family of n-dimensional diffusions, taking values in the unit simplex of vectors with nonnegative coordinates that add up to one. These processes satisfy stochastic differential equations which are similar to the ones for the…

Probability · Mathematics 2013-03-15 Soumik Pal

We consider the task of filtering a dynamic parameter evolving as a diffusion process, given data collected at discrete times from a likelihood which is conjugate to the marginal law of the diffusion, when a generic dual process on a…

Probability · Mathematics 2023-11-29 Guillaume Kon Kam King , Andrea Pandolfi , Marco Piretto , Matteo Ruggiero

We consider diffusion processes x_{t} on the unit interval. Doob-transformation techniques consist of a selection of x_{t}-paths procedure. The law of the transformed process is the one of a branching diffusion system of particles, each…

Quantitative Methods · Quantitative Biology 2011-07-15 Thierry Huillet

In populations competing for resources, it is natural to ask whether consuming fewer resources provides any selective advantage. To answer this question, we propose a Wright- Fisher model with two types of individuals: the inefficient…

Probability · Mathematics 2020-09-11 Adrian Gonzalez Casanova , Veronica Miro Pina , Juan Carlos Pardo

Learning dynamical systems from sparse observations is critical in numerous fields, including biology, finance, and physics. Even if tackling such problems is standard in general information fusion, it remains challenging for contemporary…

Machine Learning · Computer Science 2024-06-04 Ella Tamir , Arno Solin

This paper is concerned with exploring the microscopic basis for the discrete versions of the standard replicator equation and the adjusted replicator equation. To this end, we introduce frequency-dependent selection -- as a result of…

Populations and Evolution · Quantitative Biology 2021-02-19 Archan Mukhopadhyay , Sagar Chakraborty

By means of the Ito-Nisio theorem, we introduce and discuss a general approach to series representations of path integrals. We then argue that the optimal basis for both ``primitive'' and partial averaged approaches is the Wiener…

Chemical Physics · Physics 2009-11-07 Cristian Predescu , J. D. Doll

In nuclear and particle physics one is often faced with problems where perturbation theory is not applicable. An example of this is the description of bound states. Therefore, an exact solution of field theory to all orders is an…

High Energy Physics - Phenomenology · Physics 2009-10-31 Cetin Savkli

A dynamical picture of phylogenetic evolution is given in terms of Markov models on a state space, comprising joint probability distributions for character types of taxonomic classes. Phylogenetic branching is a process which augments the…

Populations and Evolution · Quantitative Biology 2009-11-10 P. D. Jarvis , J. D. Bashford , J. G. Sumner

Moran or Wright-Fisher processes are probably the most well known model to study the evolution of a population under various effects. Our object of study will be the Simpson index which measures the level of diversity of the population, one…

Probability · Mathematics 2018-09-25 Arnaud Personne , Arnaud Guillin , Franck Jabot , Arnaud Guillin

The kinetics of collective rearrangements in solution, such as protein folding and nanocrystal phase transitions, often involve free energy barriers that are both long and rough. Applying methods of transition path sampling to harvest…

Statistical Mechanics · Physics 2009-11-13 M. Grünwald , P. L. Geissler , C. Dellago

We study the multi-strategy stochastic evolutionary game with death-birth updating in expanding spatial populations of size $N\to \infty$. The model is a voter model perturbation. For typical populations, we require perturbation strengths…

Probability · Mathematics 2021-01-13 Yu-Ting Chen

Particle smoothing methods are used for inference of stochastic processes based on noisy observations. Typically, the estimation of the marginal posterior distribution given all observations is cumbersome and computational intensive. In…

Machine Learning · Computer Science 2017-05-24 H. -Ch. Ruiz , H. J. Kappen

The aim of the presented research is to give a rigorous mathematical approach to Feynman path integrals based on strong (pathwise) approximations based on simple random walks.

Mathematical Physics · Physics 2018-03-22 Tamás Szabados

In this paper we use splitting technique to estimate the probability of hitting a rare but critical set by the continuous component of a switching diffusion. Instead of following classical approach we use Wonham filter to achieve multiple…

Probability · Mathematics 2014-12-19 Anindya Goswami , François Le Gland

As an alternative but unified and more fundamental description for quantum physics, Feynman path integrals generalize the classical action principle to a probabilistic perspective, under which the physical observables' estimation translates…

High Energy Physics - Lattice · Physics 2023-03-03 Shile Chen , Oleh Savchuk , Shiqi Zheng , Baoyi Chen , Horst Stoecker , Lingxiao Wang , Kai Zhou

Using a recent path integral representation for the T-matrix in nonrelativistic potential scattering we investigate new variational approximations in this framework. By means of the Feynman-Jensen variational principle and the most general…

Nuclear Theory · Physics 2010-08-25 J. Carron , R. Rosenfelder