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Transcranial ultrasonic stimulation (TUS) has the potential to usher in a new era for human neuroscience by allowing spatially precise and high-resolution non-invasive targeting of both deep and superficial brain regions. Currently,…

Ultrasonic cavitation is being used in medical applications as a way to influence matter, such as tissue or drug vehicles, on a micro-scale. Oscillating or collapsing cavitation bubbles provide transient mechanical force fields, which can,…

Medical Physics · Physics 2022-06-15 Emanuele Perra , Nick Hayward , Kenneth P. H. Pritzker , Heikki J. Nieminen

Neuronal excitability is known to be affected by transcranial electrical stimulation. However, due to the existence of both excitatory and inhibitory neurons in the cortex, the mechanism of neuronal excitability shift is still not clear.…

Neurons and Cognition · Quantitative Biology 2019-08-23 Jiahui Wang , Hao Wang , Xin Yuan Thow , Nitish V. Thakor

Low-intensity transcranial focused ultrasound (tFUS) is rapidly emerging as a transformative non-invasive brain stimulation (NIBS) modality characterized by high spatial resolution and ability to target deep brain circuits. Unlike…

Neurons and Cognition · Quantitative Biology 2026-04-02 William J. Tyler

Objective. While ultrasound is largely established for use in diagnostic imaging and heating therapies, its application for neuromodulation is relatively new and not well understood. The objective of the present study was to investigate…

Tissues and Organs · Quantitative Biology 2015-03-09 Jerel K. Mueller , Wynn Legon , William J. Tyler

This paper presents a short selective review of the non-thermal weak microwave field impact on a nerve fiber. The published results of recent experiments are reviewed and analyzed. The theory of the authors is presented, according to which…

Biological Physics · Physics 2014-11-25 M. N. Shneider , M. Pekker

Nerve stimulation via micro-electrode implants is one of the neurostimulation approaches which is used frequently in the medical treatment of some brain disorders, neural prosthetics, brain-machine interfaces and also in the cyborg. In this…

Biological Physics · Physics 2019-04-30 Yousef Jamali , Mohammad Jamali , Mehdi Golshani

A hearing sensation arises when the elastic basilar membrane inside the cochlea vibrates. The basilar membrane is typically set into motion through airborne sound that displaces the middle ear and induces a pressure difference across the…

Quantitative Methods · Quantitative Biology 2015-06-22 T. Tchumatchenko , T. Reichenbach

Living systems implement and execute an extraordinary plethora of computational tasks. The inherent degree of large scale coordination emerges as a global property, from the intricate sea of microscopic interactions. The brain, with its…

Disordered Systems and Neural Networks · Physics 2018-01-03 Duccio Fanelli , Francesco Ginelli , Roberto Livi , Niccolò Zagli , Clement Zankoc

Cochlear implants (CIs) are devices that restore the sense of hearing in people with severe sensorineural hearing loss. An electrode array inserted in the cochlea bypasses the natural transducer mechanism that transforms mechanical sound…

Neurons and Cognition · Quantitative Biology 2025-01-30 Franklin Alvarez , Yixuan Zhang , Daniel Kipping , Waldo Nogueira

The excitability property of spiking neurons describes their capability to output an action potential as a real-time response to an input synaptic excitation current and is central to the event-based neuromorphic computing paradigm. The…

Statistical Mechanics · Physics 2025-11-18 Léopold Van Brandt , Grégoire Brandsteert , Denis Flandre

In the cerebral cortex, neurons are subject to a continuous bombardment of synaptic inputs originating from the network's background activity. This leads to ongoing, mostly subthreshold membrane dynamics that depends on the statistics of…

Biological Physics · Physics 2009-11-07 Ulrich Hillenbrand

In the present work, electroencephalographic recordings of healthy human participants were performed to study the entrainment of brainwaves using a variety of stimulus. First, periodic entrainment of the brainwaves was studied using two…

Neurons and Cognition · Quantitative Biology 2019-01-04 Richa Phogat , P. Parmananda

Cellular-level neuron stimulation has attracted much attention in the areas of prevention, diagnosis and treatment of neurological disorders. Herein, we propose a spintronic neurostimulator based on the domain wall movement inside…

Medical Physics · Physics 2020-01-08 Diqing Su , Kai Wu , Renata Saha , Jian-Ping Wang

We report theory, measurements and numerical simulations on nonlinear piezoelectric ultrasonic devices with stable limit cycles. The devices are shown to exhibit behavior familiar from the theory of coupled auto-oscillators. Frequency of…

Classical Physics · Physics 2007-05-23 Richard L Weaver , Oleg I Lobkis , Alexey Yamilov

The way nuclear motion affects electronic responses has become a very hot topic in materials science. Coherent acoustic phonons can dynamically modify optical, magnetic and mechanical properties at ultrasonic frequencies, with promising…

Mesoscale and Nanoscale Physics · Physics 2018-08-29 Edoardo Baldini , Tania Palmieri , Adriel Dominguez , Pascal Ruello , Angel Rubio , Majed Chergui

In the emerging research field of bioelectronic medicine, it has been indicated that neuromodulation of the Vagus Nerve (VN) has the potential to treat various conditions such as epilepsy, depression, and autoimmune diseases. In order to…

Nonlinear phononics play important role in strong laser-solid interactions. We discuss nonlinear dynamical protocols which allow for efficient excitation and control of nonlinear phonons. We consider recent inspiring proposals: inducing…

Other Condensed Matter · Physics 2018-05-16 A. P. Itin , M. I. Katsnelson

Objective: The brain operates via generation, transmission and integration of neuronal signals and most neurological disorders are related to perturbation of these processes. Neurostimulation by Focused Ultrasound (FUS) is a promising…

We theoretically describe how weak signals may be efficiently transmitted throughout more than one frequency range in noisy excitable media by kind of stochastic multiresonance. This serves us here to reinterpret recent experiments in…

Data Analysis, Statistics and Probability · Physics 2015-05-27 J. J. Torres , J. Marro , J. F. Mejias
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