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Applications of Implicit Neural Representations (INRs) have emerged as a promising deep learning approach for compactly representing large volumetric datasets. These models can act as surrogates for volume data, enabling efficient storage…

Machine Learning · Computer Science 2026-01-27 Shanu Saklani , Tushar M. Athawale , Nairita Pal , David Pugmire , Christopher R. Johnson , Soumya Dutta

Simulated high-dimensional data is useful for testing, validating, and improving algorithms used in dimension reduction, supervised and unsupervised learning. High-dimensional data is characterized by multiple variables that are dependent…

Understanding molecular structure, dynamics, and reactivity requires bridging processes that occur across widely separated time scales. Conventional molecular dynamics simulations provide atomistic resolution, but their femtosecond time…

Chemical Physics · Physics 2025-10-10 Juan Viguera Diez , Mathias Schreiner , Simon Olsson

Collective variables (CVs) are low-dimensional projections of high-dimensional system states. They are used to gain insights into complex emergent dynamical behaviors of processes on networks. The relation between CVs and network measures…

Physics and Society · Physics 2026-03-19 Marvin Lücke , Stefanie Winkelmann , Jobst Heitzig , Nora Molkenthin , Péter Koltai

Obtaining a rigorous and reliable method for linking computer simulations of polymer blends and composites at different length scales of interest is a highly desirable goal in soft matter physics. In this paper a multiscale modeling…

Soft Condensed Matter · Physics 2015-05-19 J. McCarty , M. G. Guenza

As an effective way to integrate the information contained in multiple medical images under different modalities, medical image synthesis and fusion have emerged in various clinical applications such as disease diagnosis and treatment…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Yuhao Wang , Ruirui Liu , Zihao Li , Cailian Yang , Qiegen Liu

We present a method of parameter estimation for large class of nonlinear systems, namely those in which the state consists of output derivatives and the flow is linear in the parameter. The method, which solves for the unknown parameter by…

Systems and Control · Electrical Eng. & Systems 2024-07-16 Simon Kuang , Xinfan Lin

Simulation of reasonable timescales for any long physical process using molecular dynamics (MD) is a major challenge in computational physics. In this study, we have implemented an approach based on multi-fidelity physics informed neural…

Computational Physics · Physics 2020-12-08 Mahmudul Islam , Md Shajedul Hoque Thakur , Satyajit Mojumder , Mohammad Nasim Hasan

High-dimensional metastable molecular system can often be characterised by a few features of the system, i.e. collective variables (CVs). Thanks to the rapid advance in the area of machine learning and deep learning, various deep…

Machine Learning · Computer Science 2023-08-10 Wei Zhang , Christof Schütte

Vortex-induced vibration (VIV) is a typical nonlinear fluid-structure interaction phenomenon, which widely exists in practical engineering (the flexible riser, the bridge and the aircraft wing, etc). The conventional finite element model…

Fluid Dynamics · Physics 2021-12-30 Hesheng Tang , Hu Yang , Yangyang Liao , Liyu Xie

This paper discusses a novel initialization algorithm for the estimation of nonlinear state-space models. Good initial values for the model parameters are obtained by identifying separately the linear dynamics and the nonlinear terms in the…

Systems and Control · Computer Science 2018-04-25 A. Marconato , J. Sjöberg , J. A. K. Suykens , J. Schoukens

Nonlinear stochastic motion presents significant challenges for Bayesian particle tracking. To address this challenge, this paper proposes a framework to construct an invertible transformation that maps the nonlinear state-space model (SSM)…

Methodology · Statistics 2026-04-13 Yonatan L. Ashenafi

Many physical systems characterized by nonlinear multiscale interactions can be effectively modeled by treating unresolved degrees of freedom as random fluctuations. However, even when the microscopic governing equations and qualitative…

Statistical Mechanics · Physics 2021-06-07 Jared L. Callaham , Jean-Christophe Loiseau , Georgios Rigas , Steven L. Brunton

Finding proper collective variables for complex systems and processes is one of the most challenging tasks in simulations, which limits the interpretation of experimental and simulated data and the application of enhanced sampling…

Recently, several approaches for multiscale simulations for problems with high contrast and no scale separation are introduced. Among them is the nonlocal multicontinua (NLMC) method, which introduces multiple macroscopic variables in each…

Numerical Analysis · Mathematics 2020-01-23 Eric T. Chung , Y. Efendiev , Wing T. Leung , ans M. Vasilyeva

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

Biomolecules · Quantitative Biology 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

Estimating the state of a dynamical system from a series of noise-corrupted observations is fundamental in many areas of science and engineering. The most well-known method, the Kalman smoother (and the related Kalman filter), relies on…

Machine Learning · Statistics 2017-04-24 Luca Ambrogioni , Umut Güçlü , Eric Maris , Marcel van Gerven

Large molecular dynamics simulations (millions of atoms, tens of microseconds, thousands of processors) hit the strong scalability wall: simulation on twice as many processors does not take half the time. Inspired by large N-body space…

Numerical Analysis · Computer Science 2013-10-21 Jana Pazúriková , Luděk Matyska

We propose a flexible yet interpretable model for high-dimensional data with time-varying second order statistics, motivated and applied to functional neuroimaging data. Motivated by the neuroscience literature, we factorize the covariances…

Machine Learning · Statistics 2021-07-20 Katherine Tsai , Mladen Kolar , Oluwasanmi Koyejo

Classical simulation of real-space quantum dynamics is challenging due to the exponential scaling of computational cost with system dimensions. Quantum computer offers the potential to simulate quantum dynamics with polynomial complexity;…

Quantum Physics · Physics 2021-10-13 Chee-Kong Lee , Chang-Yu Hsieh , Shengyu Zhang , Liang Shi