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Crop yield is a highly complex trait determined by multiple factors such as genotype, environment, and their interactions. Accurate yield prediction requires fundamental understanding of the functional relationship between yield and these…

Machine Learning · Computer Science 2019-06-12 Saeed Khaki , Lizhi Wang

Maize, a crucial crop globally cultivated across vast regions, especially in sub-Saharan Africa, Asia, and Latin America, occupies 197 million hectares as of 2021. Various statistical and machine learning models, including mixed-effect…

Machine Learning · Statistics 2024-05-13 Lorenzo Valleggi , Marco Scutari , Federico Mattia Stefanini

Heritability is a central parameter in quantitative genetics, both from an evolutionary and a breeding perspective. For plant traits heritability is traditionally estimated by comparing within and between genotype variability. This approach…

Global food security depends on predicting crop responses to climate variability, yet process based crop models remain too computationally expensive for large scale exploration of genotype and environment interactions. Here we develop a…

Computational Engineering, Finance, and Science · Computer Science 2026-05-25 Mojdeh Saadati , Juan Panelo , Gustavo Visentini , Soumik Sarkar , Carlos Messina , Baskar Ganapathysubramanian

The presence of phenomena analogous to phase transition in Statistical Mechanics, has been suggested in the evolution of a polygenic trait under stabilizing selection, mutation and genetic drift. By using numerical simulations of a model…

Populations and Evolution · Quantitative Biology 2017-02-13 Annalisa Fierro , Sergio Cocozza , Antonella Monticelli , Giovanni Scala , Gennaro Miele

Large populations may contain numerous simultaneously segregating polymorphisms subject to natural selection. Since selection acts on individuals whose fitness depends on many loci, different loci affect each other's dynamics. This leads to…

Populations and Evolution · Quantitative Biology 2011-08-09 Richard A. Neher , Boris I. Shraiman

Biochemical and regulatory interactions central to biological networks are expected to cause extensive genetic interactions or epistasis affecting the heritability of complex traits and the distribution of genotypes in populations. However,…

Populations and Evolution · Quantitative Biology 2009-12-15 Richard A. Neher , Boris I. Shraiman

Recruitment dynamics, or the distribution of the number of offspring among individuals, is central for understanding ecology and evolution. Sweepstakes reproduction (heavy right-tailed offspring number distribution) is central for…

Populations and Evolution · Quantitative Biology 2026-01-16 Bjarki Eldon

Genetic diversity is central to the process of evolution. Both natural selection and random genetic drift are influenced by the level of genetic diversity of a population; selection acts on diversity while drift samples from it. At a given…

Populations and Evolution · Quantitative Biology 2024-11-12 Nikolas Vellnow , Toni I. Gossmann , David Waxman

Background: Hybridogenesis is a very interesting example of reproduction which seems to integrate the sexual and clonal processes in one system. In a case of frogs, described in the paper, two parental species - Rana lessonae and Rana…

Genomics · Quantitative Biology 2009-03-18 Mateusz Kula , Katarzyna Bonkowska , Maria Ogielska , Piotr Kierzkowski , Anna Zalesna , Stanislaw Cebrat

Plant breeding and variety trials are usually conducted in multiple environments sampled from a defined target population of environments in order to characterize the performance of breeding lines or varieties. When the population is large…

Applications · Statistics 2026-05-01 Maryna Prus , Lenka Filová , Hans-Peter Piepho , Waqas Ahmed Malik

Inferring dependencies between complex biological traits while accounting for evolutionary relationships between specimens is of great scientific interest yet remains infeasible when trait and specimen counts grow large. The…

A genome-wide association study (GWAS) correlates marker variation with trait variation in a sample of individuals. Each study subject is genotyped at a multitude of SNPs (single nucleotide polymorphisms) spanning the genome. Here we assume…

Machine Learning · Statistics 2019-01-14 Kevin L. Keys , Gary K. Chen , Kenneth Lange

Horizontal gene transfer is an important factor in bacterial evolution that can act across species boundaries. Yet, we know little about rate and genomic targets of cross-lineage gene transfer, and about its effects on the recipient…

Populations and Evolution · Quantitative Biology 2022-10-12 Jeffrey J. Power , Fernanda Pinheiro , Simone Pompei , Viera Kovacova , Melih Yüksel , Isabel Rathmann , Mona Förster , Michael Lässig , Berenike Maier

We review and extend results for mutation, selection, genetic drift, and migration in a one-dimensional continuous population. The population is described by a continuous limit of the stepping stone model, which leads to the stochastic…

Populations and Evolution · Quantitative Biology 2011-04-14 K. S. Korolev , Mikkel Avlund , Oskar Hallatschek , David R. Nelson

To learn about the past from a sample of genomic sequences, one needs to understand how evolutionary processes shape genetic diversity. Most population genetic inference is based on frameworks assuming adaptive evolution is rare. But if…

Populations and Evolution · Quantitative Biology 2014-03-25 Richard A. Neher

Rapid adaptation has been observed in numerous organisms in response to selective pressures, such as the application of pesticides and the presence of pathogens. When rapid adaptation is driven by rare alleles from the standing genetic…

Populations and Evolution · Quantitative Biology 2014-11-04 Nandita R. Garud , Philipp W. Messer , Erkan O. Buzbas , Dmitri A. Petrov

Genomic prediction can be a powerful tool to achieve greater rates of genetic gain for quantitative traits if thoroughly integrated into a breeding strategy. In rice as in other crops, the interest in genomic prediction is very strong with…

Genomics · Quantitative Biology 2021-10-01 Jérôme Bartholomé , Parthiban Thathapalli Prakash , Joshua N. Cobb

Population genetics models typically consider a fixed population size and a unique selection coefficient. However, population dynamics inherently generate noise in numbers of individuals and selection acts on various components of the…

Populations and Evolution · Quantitative Biology 2017-12-12 Lukas Heinrich , Johannes Müller , Aurélien Tellier , Daniel Zivković

Plant domestication involved a process of selection through human agency of a series of traits collectively termed the domestication syndrome. Current debate concerns the pace at which domesticated plants emerged from cultivated wild…

Populations and Evolution · Quantitative Biology 2014-03-06 Robin G. Allaby , Dorian Q. Fuller , James L. Kitchen