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Sampling considerations limit the experimental conditions under which information theoretic analyses of neurophysiological data yield reliable results. We develop a procedure for computing the full temporal entropy and information of…

Biological Physics · Physics 2009-11-06 Simon R. Schultz , Stefano Panzeri

Many properties of perceptual decision making are well-modeled by deep neural networks. However, such architectures typically treat decisions as instantaneous readouts, overlooking the temporal dynamics of the decision process. We present…

Neurons and Cognition · Quantitative Biology 2025-11-25 Hayden R. Johnson , Anastasia N. Krouglova , Hadi Vafaii , Jacob L. Yates , Pedro J. Gonçalves

In this work we study the detection of weak stimuli by spiking neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present…

Neurons and Cognition · Quantitative Biology 2009-06-04 Jorge F. Mejias , Joaquin J. Torres

Knowledge about the collective dynamics of cortical spiking is very informative about the underlying coding principles. However, even most basic properties are not known with certainty, because their assessment is hampered by spatial…

Neurons and Cognition · Quantitative Biology 2019-03-13 Jens Wilting , Viola Priesemann

We recently reported the existence of fluctuations in neural signals that may permit neurons to code multiple simultaneous stimuli sequentially across time. This required deploying a novel statistical approach to permit investigation of…

Neurons and Cognition · Quantitative Biology 2020-02-03 Jeff T. Mohl , Valeria C. Caruso , Surya T. Tokdar , Jennifer M. Groh

Two universal functional principles of Adaptive Resonance Theory simulate the brain code of all biological learning and adaptive intelligence. Low level representations of multisensory stimuli in their immediate environmental context are…

Neurons and Cognition · Quantitative Biology 2023-03-06 Birgitta Dresp-Langley

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

There is growing evidence regarding the importance of spike timing in neural information processing, with even a small number of spikes carrying information, but computational models lag significantly behind those for rate coding.…

Neurons and Cognition · Quantitative Biology 2018-03-13 Zhinus Marzi , Joao Hespanha , Upamanyu Madhow

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Spike correlations between neurons are ubiquitous in the cortex, but their role is at present not understood. Here we describe the firing response of a leaky integrate-and-fire neuron (LIF) when it receives a temporarily correlated input…

Neurons and Cognition · Quantitative Biology 2007-10-15 Ruben Moreno-Bote , Alfonso Renart , Nestor Parga

We consider the evolution of a network of neurons, focusing on the asymptotic behavior of spikes dynamics instead of membrane potential dynamics. The spike response is not sought as a deterministic response in this context, but as a…

Data Analysis, Statistics and Probability · Physics 2010-08-27 J. C. Vasquez , B. Cessac , T. Viéville

How do neuronal populations encode time-dependent stimuli in their population firing rate? To address this question, I consider the quasi-renewal equation and the event-based expansion, two theoretical approximations proposed recently, and…

Neurons and Cognition · Quantitative Biology 2013-12-04 Richard Naud

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

In the light of recent experimental findings that gap junctions are essential for low level intensity detection in the sensory periphery, the Greenberg-Hastings cellular automaton is employed to model the response of a two-dimensional…

Neurons and Cognition · Quantitative Biology 2016-09-08 Mauro Copelli , Osame Kinouchi

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

Statistical Mechanics · Physics 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

In terms of the long-distance communication of a single neuron, interpulse intervals (IPIs) are a possible alternative to rate and binary codes. As a proxy for IPI, the time-to-spike (TTS) for a neuron can be found in the biophysical and…

Neurons and Cognition · Quantitative Biology 2019-01-15 Chandan Singh , William B. Levy

Rhythmic activities that alternate between coherent and incoherent phases are ubiquitous in chemical, ecological, climate, or neural systems. Despite their importance, general mechanisms for their emergence are little understood. In order…

Adaptation and Self-Organizing Systems · Physics 2022-06-01 Max Thiele , Rico Berner , Peter A. Tass , Eckehard Schöll , Serhiy Yanchuk

Neural responses are highly variable, and some portion of this variability arises from fluctuations in modulatory factors that alter their gain, such as adaptation, attention, arousal, expected or actual reward, emotion, and local metabolic…

Neurons and Cognition · Quantitative Biology 2015-07-08 Neil C. Rabinowitz , Robbe L. T. Goris , Johannes Ballé , Eero P. Simoncelli

One of the fundamental characteristics of a nonlinear system is how it transfers correlations in its inputs to correlations in its outputs. This is particularly important in the nervous system, where correlations between spiking neurons are…

Neurons and Cognition · Quantitative Biology 2013-05-29 Eric Shea-Brown , Kresimir Josic , Jaime de la Rocha , Brent Doiron
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