English
Related papers

Related papers: Agalma: an automated phylogenomics workflow

200 papers

Since the arrival of next-generation sequencing technologies the amount of genetic sequencing data has increased dramatically. This has has fueled an increase in human genetics research. At the same time, with the recent advent of…

Genomics · Quantitative Biology 2016-07-04 Kristiina Ausmees , Pushpam Aji John

Recent advances in large language models (LLMs) transform how machine learning (ML) pipelines are developed and evaluated. LLMs enable a new type of workload, agentic pipeline search, in which autonomous or semi-autonomous agents generate,…

Databases · Computer Science 2026-03-06 Arnab Phani , Elias Strauss , Sebastian Schelter

The use of Large Language Models (LLMs) has drawn growing interest within the scientific community. LLMs can handle large volumes of textual data and support methods for evidence synthesis. Although recent studies highlight the potential of…

Software Engineering · Computer Science 2026-02-12 Cauã Ferreira Barros , Marcos Kalinowski , Mohamad Kassab , Valdemar Vicente Graciano Neto

Motivation: The rapid growth in genome-wide association studies (GWAS) in plants and animals has brought about the need for a central resource that facilitates i) performing GWAS, ii) accessing data and results of other GWAS, and iii)…

By simply composing prompts, developers can prototype novel generative applications with Large Language Models (LLMs). To refine prototypes into products, however, developers must iteratively revise prompts by evaluating outputs to diagnose…

Human-Computer Interaction · Computer Science 2024-02-28 Tae Soo Kim , Yoonjoo Lee , Jamin Shin , Young-Ho Kim , Juho Kim

Large Language Models (LLMs) have shown strong general capabilities in many applications. However, how to make them reliable tools for some specific tasks such as automated short answer grading (ASAG) remains a challenge. We present SteLLA…

Computation and Language · Computer Science 2025-05-26 Hefei Qiu , Brian White , Ashley Ding , Reinaldo Costa , Ali Hachem , Wei Ding , Ping Chen

The exponential growth of academic publications poses challenges for the research process, such as literature review and procedural planning. Large Language Models (LLMs) have emerged as powerful AI tools, especially when combined with…

Applied Physics · Physics 2025-02-13 Joaquin Ramirez-Medina , Mohammadmehdi Ataei , Alidad Amirfazli

Structuring data analysis projects, that is, defining the layout of files and folders needed to analyze data using existing tools and novel code, largely follows personal preferences. In this work, we look at the structure of several data…

Human-Computer Interaction · Computer Science 2024-10-15 Luca Visentin , Luca Munaron , Federico Alessandro Ruffinatti

Recent approaches to large language model (LLM) alignment typically require millions of human annotations or rely on external aligned models for synthetic data generation. This paper introduces ALMA: Alignment with Minimal Annotation,…

Computation and Language · Computer Science 2024-12-06 Michihiro Yasunaga , Leonid Shamis , Chunting Zhou , Andrew Cohen , Jason Weston , Luke Zettlemoyer , Marjan Ghazvininejad

Datasets play a central role in AI governance by enabling both evaluation (measuring capabilities) and alignment (enforcing values) along axes such as helpfulness, harmlessness, toxicity, quality, and more. However, most alignment and…

Computers and Society · Computer Science 2025-07-16 Prajna Soni , Deepika Raman , Dylan Hadfield-Menell

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Maintaining comprehensive and up-to-date knowledge graphs (KGs) is critical for modern AI systems, but manual curation struggles to scale with the rapid growth of scientific literature. This paper presents KARMA, a novel framework employing…

Computation and Language · Computer Science 2026-01-13 Yuxing Lu , Wei Wu , Xukai Zhao , Rui Peng , Jinzhuo Wang

The BioModels database is one of the premier databases for computational models in systems biology. The database contains over 1000 curated models and an even larger number of non-curated models. All the models are stored in the…

Molecular Networks · Quantitative Biology 2026-02-02 Bhavyahshree Navaneetha Krishnan , Adel Heydarabadipour , Herbert Sauro

The advent of Large Language Models (LLMs) has created new opportunities for the automation of scientific research spanning both experimental processes and computational simulations. This study explores the feasibility of constructing an…

Artificial Intelligence · Computer Science 2025-01-16 Zhihan Liu , Yubo Chai , Jianfeng Li

The understanding of large-scale scientific software poses significant challenges due to its diverse codebase, extensive code length, and target computing architectures. The emergence of generative AI, specifically large language models…

Software Engineering · Computer Science 2024-03-19 Kareem Shaik , Dali Wang , Weijian Zheng , Qinglei Cao , Heng Fan , Peter Schwartz , Yunhe Feng

Deductive coding is a widely used qualitative research method for determining the prevalence of themes across documents. While useful, deductive coding is often burdensome and time consuming since it requires researchers to read, interpret,…

Computation and Language · Computer Science 2023-06-28 Robert Chew , John Bollenbacher , Michael Wenger , Jessica Speer , Annice Kim

With the exponential increase of the protein sequence databases over time, multiple-sequence alignment (MSA) methods, like PSI-BLAST, perform exhaustive and time-consuming database search to retrieve evolutionary information. The resulting…

Quantitative Methods · Quantitative Biology 2023-08-21 Issar Arab

System-level audit logs often play a critical role in computer forensics. They capture low-level interactions between programs and users in much detail, making them a rich source of insight and provenance on malicious user activity.…

Cryptography and Security · Computer Science 2020-04-22 Omid Setayeshfar , Christian Adkins , Matthew Jones , Kyu Hyung Lee , Prashant Doshi

Compact Genetic Algorithms (cGAs) are condensed variants of classical Genetic Algorithms (GAs) that use a probability vector representation of the population instead of the complete population. cGAs have been shown to significantly reduce…

Neural and Evolutionary Computing · Computer Science 2025-04-07 Prasanta Dutta , Anirban Mukhopadhyay

This study introduces AGGA, a dataset comprising 80 academic guidelines for the use of Generative AIs (GAIs) and Large Language Models (LLMs) in academic settings, meticulously collected from official university websites. The dataset…

Computation and Language · Computer Science 2025-03-19 Junfeng Jiao , Saleh Afroogh , Kevin Chen , David Atkinson , Amit Dhurandhar