English
Related papers

Related papers: Agalma: an automated phylogenomics workflow

200 papers

The LLM-as-a-judge paradigm enables flexible, user-defined evaluation, but its effectiveness is often limited by the scarcity of diverse, representative data for refining criteria. We present a tool that integrates synthetic data generation…

Human-Computer Interaction · Computer Science 2025-11-07 Hyo Jin Do , Zahra Ashktorab , Jasmina Gajcin , Erik Miehling , Martín Santillán Cooper , Qian Pan , Elizabeth M. Daly , Werner Geyer

Circular genome visualizations are essential for exploring structural variants and gene regulation. However, existing tools often require complex scripting and manual configuration, making the process time-consuming, error-prone, and…

Genomics · Quantitative Biology 2025-07-08 Chi Zhang , Yu Dong , Yang Wang , Yuetong Han , Guihua Shan , Bixia Tang

To perform effective causal inference in high-dimensional datasets, initiating the process with causal discovery is imperative, wherein a causal graph is generated based on observational data. However, obtaining a complete and accurate…

Machine Learning · Computer Science 2025-04-18 Elahe Khatibi , Mahyar Abbasian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Evolutionary Biologists have long struggled with the challenge of developing analysis workflows in a flexible manner, thus facilitating the reuse of phylogenetic knowledge. An evolutionary biology workflow can be viewed as a plan which…

Artificial Intelligence · Computer Science 2018-05-02 Thanh Hai Nguyen , Enrico Pontelli , Tran Cao Son

We present Camyla, a system for fully autonomous research within the scientific domain of medical image segmentation. Camyla transforms raw datasets into literature-grounded research proposals, executable experiments, and complete…

Artificial Intelligence · Computer Science 2026-04-14 Yifan Gao , Haoyue Li , Feng Yuan , Xin Gao , Weiran Huang , Xiaosong Wang

Scientific research increasingly relies on specialized computational tools, yet effectively utilizing these tools demands substantial domain expertise. While Large Language Models (LLMs) show promise in tool automation, they struggle to…

Artificial Intelligence · Computer Science 2025-07-29 Keyan Ding , Jing Yu , Junjie Huang , Yuchen Yang , Qiang Zhang , Huajun Chen

Probabilistic programming frameworks are powerful tools for statistical modelling and inference. They are not immediately generalisable to phylogenetic problems due to the particular computational properties of the phylogenetic tree object.…

Populations and Evolution · Quantitative Biology 2022-11-11 Christiaan Swanepoel , Mathieu Fourment , Xiang Ji , Hassan Nasif , Marc A Suchard , Frederick A Matsen , Alexei Drummond

In qualitative research, data transcription is often labor-intensive and time-consuming. To expedite this process, a workflow utilizing artificial intelligence (AI) was developed. This workflow not only enhances transcription speed but also…

Computation and Language · Computer Science 2025-04-22 Jakob Sponholz , Andreas Weilinghoff , Juliane Schopf

We describe the calibration and imaging heuristics developed and deployed in the ALMA interferometric data processing pipeline, as of ALMA Cycle 9. The pipeline software framework is written in Python, with each data reduction stage layered…

Under the impact of global climate changes and human activities, harmful algae blooms in surface waters have become a growing concern due to negative impacts on water related industries. Therefore, reliable and cost effective methods of…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Jason L. Deglint , Chao Jin , Alexander Wong

This paper introduces AnalyticsGPT, an intuitive and efficient large language model (LLM)-powered workflow for scientometric question answering. This underrepresented downstream task addresses the subcategory of meta-scientific questions…

Computation and Language · Computer Science 2026-02-11 Khang Ly , Georgios Cheirmpos , Adrian Raudaschl , Christopher James , Seyed Amin Tabatabaei

Phylogenomics heavily relies on well-curated sequence data sets that consist, for each gene, exclusively of 1:1-orthologous. Paralogs are treated as a dangerous nuisance that has to be detected and removed. We show here that this severe…

Discrete Mathematics · Computer Science 2017-12-19 Marc Hellmuth , Nicolas Wieseke , Marcus Lechner , Hans-Peter Lenhof , Martin Middendorf , Peter F. Stadler

Large language models excel in many human-language tasks but often falter in highly specialized domains like scholarly astronomy. To bridge this gap, we introduce AstroLLaMA, a 7-billion-parameter model fine-tuned from LLaMA-2 using over…

The last twenty years have witnessed molecular data emerge as a primary research instrument in most branches of mycology. Fungal systematics, taxonomy, and ecology have all seen tremendous progress and have undergone rapid, far-reaching…

Machine learning (ML) offers powerful methods for detecting and modeling associations often in data with large feature spaces and complex associations. Many useful tools/packages (e.g. scikit-learn) have been developed to make the various…

Machine Learning · Computer Science 2022-06-27 Ryan J. Urbanowicz , Robert Zhang , Yuhan Cui , Pranshu Suri

With the advance in genome sequencing technology, the lengths of deoxyribonucleic acid (DNA) sequencing results are rapidly increasing at lower prices than ever. However, the longer lengths come at the cost of a heavy computational burden…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-12 Seongyeon Park , Junguk Hong , Jaeyong Song , Hajin Kim , Youngsok Kim , Jinho Lee

Logs provide users with useful insights to help with a variety of development and operations tasks. The problem is that logs are often unstructured, making their analysis a complex task. This is mainly due to the lack of guidelines and best…

Software Engineering · Computer Science 2021-11-01 Issam Sedki , Abdelwahab Hamou-Lhadj , Otmane Ait-Mohamed

Tables, figures, and listings (TFLs) are essential tools for summarizing clinical trial data. Creation of TFLs for reporting activities is often a time-consuming task encountered routinely during the execution of clinical trials. This study…

Computation and Language · Computer Science 2024-09-20 Yumeng Yang , Peter Krusche , Kristyn Pantoja , Cheng Shi , Ethan Ludmir , Kirk Roberts , Gen Zhu

Allergens, typically proteins capable of triggering adverse immune responses, represent a significant public health challenge. To accurately identify allergen proteins, we introduce Applm (Allergen Prediction with Protein Language Models),…

Phylogenetic analysis, which allow to understand the evolution of bacterial and viral epidemics, requires large quantities of data to be analysed and processed for knowledge extraction. One of the major challenges consists on the…

Populations and Evolution · Quantitative Biology 2024-05-28 Nyckollas Brandão , André Jesus , André Páscoa , Alexandre P. Francisco , Mário Ramirez , Cátia Vaz