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Related papers: Bacterial chemotaxis without gradient-sensing

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This work concerns with a class of chemotaxis models in which external sources, comprising nonlocal and gradient-dependent damping reactions, influence the motion of a cell density attracted by a chemical signal. The mechanism of the two…

Analysis of PDEs · Mathematics 2024-06-17 Rafael Díaz Fuentes , Silvia Frassu , Giuseppe Viglialoro

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

Statistical Mechanics · Physics 2009-09-01 Pierre-Henri Chavanis

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

Statistical Mechanics · Physics 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

Active particles with their characteristic feature of self-propulsion are regarded as the simplest models for motility in living systems. The accumulation of active particles in low activity regions has led to the general belief that…

Soft Condensed Matter · Physics 2021-05-26 Hidde D. Vuijk , Holger Merlitz , Michael Lang , Abhinav Sharma , Jens-Uwe Sommer

A wide array of biological systems can navigate in shallow gradients of chemoattractant with remarkable precision. Whilst previous approaches model such systems using coarse-grained chemical density profiles, we construct a dynamical model…

Biological Physics · Physics 2023-12-19 Jacob Knight , Paula García-Galindo , Johannes Pausch , Gunnar Pruessner

Sensory systems have evolved to respond to input stimuli of certain statistical properties, and to reliably transmit this information through biochemical pathways. Hence, for an experimentally well-characterized sensory system, one ought to…

Cell Behavior · Quantitative Biology 2014-10-30 Diana Clausznitzer , Gabriele Micali , Silke Neumann , Victor Sourjik , Robert G. Endres

Kinetic-transport equations that take into account the intra-cellular pathways are now considered as the correct description of bacterial chemotaxis by run and tumble. Recent mathematical studies have shown their interest and their…

Analysis of PDEs · Mathematics 2018-06-13 Benoît Perthame , Weiran Sun , Min Tang

Many eukaryotic cells are able to sense chemical gradients by directly measuring spatial concentration differences. The precision of such gradient sensing is limited by fluctuations in the binding of diffusing particles to specific…

Cell Behavior · Quantitative Biology 2010-06-04 Bo Hu , Wen Chen , Wouter-Jan Rappel , Herbert Levine

Cells encounter a diverse array of physical and chemical signals as they navigate their natural surroundings. However, their response to the simultaneous presence of multiple cues remains elusive. Particularly, the impact of topography…

Analysis of PDEs · Mathematics 2026-03-10 Valeria Cuentas , Elio Espejo

Through evolution, bacteria have developed the ability to perform chemotactic motion in order to find nourishment. By adopting a machine learning approach, we aim to understand how this behavior arises. We consider run-and-tumble agents…

Soft Condensed Matter · Physics 2026-01-13 Nicholas Tovazzi , Gorka Muñoz-Gil , Michele Caraglio

A Keller-Segel model describes macroscopic dynamics of bacterial colonies and biological cells. Bacteria secret chemical which attracts other bacteria so that they move towards chemical gradient creating nonlocal attraction between…

Pattern Formation and Solitons · Physics 2010-05-18 Pavel M. Lushnikov

Chemotaxis, i.e. motion generated by chemical gradients, is a motility mode shared by many living species that has been developed by evolution to optimize certain biological processes such as foraging or immune response. In particular,…

Soft Condensed Matter · Physics 2023-05-24 Hugues Meyer , Heiko Rieger

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution…

Optimization and Control · Mathematics 2023-09-19 Gianni Gilardi , Andrea Signori , Jürgen Sprekels

A novel trait-structured Keller-Segel model that explores the dynamics of a migrating cell population guided by chemotaxis in response to an external ligand concentration is derived and analysed. Unlike traditional Keller-Segel models, this…

Cell Behavior · Quantitative Biology 2025-02-27 Viktoria Freingruber , Tommaso Lorenzi , Kevin J. Painter , Mariya Ptashnyk

Chemotaxis is a fundamental guidance mechanism of cells and organisms, responsible for attracting microbes to food, embryonic cells into developing tissues, immune cells to infection sites, animals towards potential mates, and…

Quantitative Methods · Quantitative Biology 2018-06-26 K. J. Painter

Bacterial chemotaxis is controlled by the signalling of a cluster of receptors. A cooperative model is presented, in which coupling between neighbouring receptor dimers enhances the sensitivity with which stimuli can be detected, without…

Biological Physics · Physics 2009-10-31 Yu Shi , Thomas Duke

We present a simple model that describes the motion of a single chemotactic cell exposed to a traveling wave of the chemoattractant. The model incorporates two types of responses to stimulation by the chemoattractant, i.e., change in…

Biological Physics · Physics 2011-10-26 Masatomo Iwasa , Ryosuke Ishiwata

It is of great biological interest to understand the molecular origins of chemotactic behavior of E. coli by developing population-level models based on the underlying signaling pathway dynamics. We derive macroscopic models for E.coli…

Analysis of PDEs · Mathematics 2016-05-06 Weiran Sun , Min Tang

The Patlak-Keller-Segel equation is a canonical model of chemotaxis to describe self-organized aggregation of organisms interacting with chemical signals. We investigate a variant of this model, assuming that the organisms exert effective…

Statistical Mechanics · Physics 2017-10-30 Seung Ki Baek , Beom Jun Kim

Many types of cells are able to accurately sense shallow gradients of chemicals across their diameters, allowing the cells to move towards or away from chemical sources. This chemotactic ability relies on the remarkable capacity of cells to…

Cell Behavior · Quantitative Biology 2015-05-13 Robert G. Endres , Ned S. Wingreen