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Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…

Medical Physics · Physics 2009-08-19 I. Reiser , J. Bian , R. M. Nishikawa , E. Y. Sidky , X. Pan

Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Yuexi Du , Regina J. Hooley , John Lewin , Nicha C. Dvornek

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…

Numerical Analysis · Mathematics 2020-07-21 Elena Morotti , Elena Loli Piccolomini

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…

Purpose: This work aims to develop an image reconstruction algorithm for wide-angle digital breast tomosynthesis (DBT) that has improved depth resolution and in-plane contrast while reducing non-uniformity artifacts. Approach: The image…

Optimization and Control · Mathematics 2026-05-29 Emil Y. Sidky , Adrian A. Sanchez , John Paul Phillips , Zheng Zhang , Dan Xia , Ingrid S. Reiser , Xiaochuan Pan

PURPOSE: We develop a practical, iterative algorithm for image-reconstruction in under-sampled tomographic systems, such as digital breast tomosynthesis (DBT). METHOD: The algorithm controls image regularity by minimizing the image total…

Full Field Digital Mammograms (FFDMs) and Digital Breast Tomosynthesis (DBT) are the two most widely used imaging modalities for breast cancer screening. Although DBT has increased cancer detection compared to FFDM, its widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Umang Sharma , Jungkyu Park , Laura Heacock , Sumit Chopra , Krzysztof Geras

Purpose: The goal of this study is to develop a novel deep learning (DL) based reconstruction framework to improve the digital breast tomosynthesis (DBT) imaging performance. Methods: In this work, the DIR-DBTnet is developed for DBT image…

Medical Physics · Physics 2021-06-09 Ting Su , Xiaolei Deng , Zhenwei Wang , Jiecheng Yang , Jianwei Chen , Hairong Zheng , Dong Liang , Yongshuai Ge

Breast cancer screening is one of the most common radiological tasks with over 39 million exams performed each year. While breast cancer screening has been one of the most studied medical imaging applications of artificial intelligence, the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Mateusz Buda , Ashirbani Saha , Ruth Walsh , Sujata Ghate , Nianyi Li , Albert Święcicki , Joseph Y. Lo , Maciej A. Mazurowski

There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Cooper's ligaments, blood vessels, and spiculated lesions. Such structures…

Medical Physics · Physics 2018-03-14 Sean D. Rose , Ingrid Reiser , Emil Y. Sidky , Xiaochuan Pan

Fiber-like features are an important aspect of breast imaging. Vessels and ducts are present in all breast images, and spiculations radiating from a mass can indicate malignancy. Accordingly, fiber objects are one of the three types of…

Medical Physics · Physics 2019-04-09 Sean D. Rose , Emil Y. Sidky , Ingrid Reiser , Xiaochuan Pan

Reconstruction of digital breast tomosynthesis is a challenging problem due to the limited angle data available in such systems. Due to memory limitations, deep learning-based methods can help improve these reconstructions, but can not…

Medical Physics · Physics 2020-09-04 Koen Michielsen , Nikita Moriakov , Jonas Teuwen , Ioannis Sechopoulos

Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sadanand Singh , Thomas Paul Matthews , Meet Shah , Brent Mombourquette , Trevor Tsue , Aaron Long , Ranya Almohsen , Stefano Pedemonte , Jason Su

Digital breast tomosynthesis is rapidly replacing digital mammography as the basic x-ray technique for evaluation of the breasts. However, the sparse sampling and limited angular range gives rise to different artifacts, which manufacturers…

Medical Physics · Physics 2018-08-15 Nikita Moriakov , Koen Michielsen , Jonas Adler , Ritse Mann , Ioannis Sechopoulos , Jonas Teuwen

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

Automated tumor detection in Digital Breast Tomosynthesis (DBT) is a difficult task due to natural tumor rarity, breast tissue variability, and high resolution. Given the scarcity of abnormal images and the abundance of normal images for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Nicholas Konz , Haoyu Dong , Maciej A. Mazurowski

Digital breast tomosynthesis (DBT) is now the standard of care for breast cancer screening in the USA. Accurate segmentation of fibroglandular tissue in DBT images is essential for personalized risk estimation, but algorithm development is…

An optimization-based image reconstruction algorithm is developed for contrast enhanced digital breast tomosynthesis (DBT) using dual-energy scanning. The algorithm minimizes directional total variation (TV) with a data discrepancy and…

The segmentation of mass lesions in digital breast tomosynthesis (DBT) images is very significant for the early screening of breast cancer. However, the high-density breast tissue often leads to high concealment of the mass lesions, which…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Haoxuan Zhang , Wenju Cui , Yuzhu Cao , Tao Tan , Jie Liu , Yunsong Peng , Jian Zheng

Digital Breast Tomosynthesis (DBT) enhances finding visibility for breast cancer detection by providing volumetric information that reduces the impact of overlapping tissues; however, limited annotated data has constrained the development…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yen Nhi Truong Vu , Dan Guo , Sripad Joshi , Harshit Kumar , Jason Su , Thomas Paul Matthews
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