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The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

We consider optimization problems involving the multiplication of variable matrices to be selected from a given family, which might be a discrete set, a continuous set or a combination of both. Such nonlinear, and possibly discrete,…

Optimization and Control · Mathematics 2021-03-12 Burak Kocuk

Crystalline materials are widely used in technological applications, yet their discovery remains a significant challenge. As their properties are driven by structure, crystal structure prediction (CSP) methods play a central role in…

Machine Learning · Computer Science 2026-04-28 Stavros Gerolymatos , J. Kyle Brubaker , Martin J. A. Schuetz , Vladimir V. Gusev

Optical proximity correction (OPC) is a widely-used resolution enhancement technique (RET) for printability optimization. Recently, rigorous numerical optimization and fast machine learning are the research focus of OPC in both academia and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Wenqian Zhao , Xufeng Yao , Ziyang Yu , Guojin Chen , Yuzhe Ma , Bei Yu , Martin D. F. Wong

An important factor in the practical implementation of optimization models is the acceptance by the intended users. This is influenced among other factors by the interpretability of the solution process. Decision rules that meet this…

Machine Learning · Computer Science 2024-12-03 Marc Goerigk , Michael Hartisch , Sebastian Merten

Optimal design of experiments for Bayesian inverse problems has recently gained wide popularity and attracted much attention, especially in the computational science and Bayesian inversion communities. An optimal design maximizes a…

Optimization and Control · Mathematics 2023-05-09 Ahmed Attia , Sven Leyffer , Todd Munson

It is classical that, when the small deformation is assumed, the incremental analysis problem of an elastoplastic structure with a piecewise-linear yield condition and a linear strain hardening model can be formulated as a convex quadratic…

Optimization and Control · Mathematics 2017-08-22 Yoshihiro Kanno

Optimization problems with norm-bounding constraints arise in a variety of applications, including portfolio optimization, machine learning, and feature selection. A common approach to these problems involves relaxing the norm constraint…

Optimization and Control · Mathematics 2025-05-08 Danial Davarnia , Mohammadreza Kiaghadi

We present an improved method for topology optimization with both adaptive mesh refinement and derefinement. Since the total volume fraction in topology optimization is usually modest, after a few initial iterations the domain of…

Numerical Analysis · Mathematics 2010-09-28 Shun Wang , Eric de Sturler , Glaucio H. Paulino

Augmented Lagrangian and optimistic primal--dual methods stabilize equality-constrained optimization through seemingly different mechanisms: the former adds constraint-dependent primal curvature, while the latter adds dual memory. Recent…

Machine Learning · Computer Science 2026-05-08 Jiayi Zhao

In several applications such as databases, planning, and sensor networks, parameters such as selectivity, load, or sensed values are known only with some associated uncertainty. The performance of such a system (as captured by some…

Data Structures and Algorithms · Computer Science 2010-01-28 Sudipto Guha , Kamesh Munagala

Gradient-based inverse design in photonics has already achieved remarkable results in designing small-footprint, high-performance optical devices. The adjoint variable method, which allows for the efficient computation of gradients, has…

In the present work we introduce a complete set of algorithms to efficiently perform adaptive refinement and coarsening by exploiting truncated hierarchical B-splines (THB-splines) defined on suitably graded isogeometric meshes, that are…

Numerical Analysis · Mathematics 2019-03-27 Massimo Carraturo , Carlotta Giannelli , Alessandro Reali , Rafael Vázquez

We present a new framework for the simultaneous optimiziation of both the topology as well as the relative density grading of cellular structures and materials, also known as lattices. Due to manufacturing constraints, the optimization…

Computational Engineering, Finance, and Science · Computer Science 2025-05-27 Jonathan Stollberg , Tarun Gangwar , Oliver Weeger , Dominik Schillinger

The semiconductor industry faces a computational crisis in extreme ultraviolet (EUV) lithography optimization, where traditional methods consume billions of CPU hours while failing to achieve sub-nanometer precision. We present a…

Machine Learning · Computer Science 2025-11-18 Rubén Darío Guerrero

Robust optimization is a common framework in optimization under uncertainty when the problem parameters are not known, but it is rather known that the parameters belong to some given uncertainty set. In the robust optimization framework the…

Optimization and Control · Mathematics 2014-02-27 Aharon Ben-Tal , Elad Hazan , Tomer Koren , Shie Mannor

Despite the success statistical physics has enjoyed at predicting the properties of materials for given parameters, the inverse problem, identifying which material parameters produce given, desired properties, is only beginning to be…

Statistical Mechanics · Physics 2016-02-17 Marc Z. Miskin , Gurdaman S. Khaira , Juan J. de Pablo , Heinrich M. Jaeger

Adaptable computing is an increasingly important paradigm that specializes system resources to variable application requirements, environmental conditions, or user requirements. Adapting computing resources to variable application…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-03 Keeley Criswell , Tosiron Adegbija

This document introduces a strategy to solve linear optimization problems. The strategy is based on the bounding condition each constraint produces on each one of the problem's dimension. The solution of a linear optimization problem is…

Optimization and Control · Mathematics 2018-09-24 Gerardo L. Febres

Differentiable optics, as an emerging paradigm that jointly optimizes optics and (optional) image processing algorithms, has made innovative optical designs possible across a broad range of applications. Many of these systems utilize…