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Suppression of excessively synchronous beta-band oscillatory activity in the brain is believed to suppress hypokinetic motor symptoms of Parkinson's disease. Recently, a lot of interest has been devoted to desynchronizing delayed feedback…

Neurons and Cognition · Quantitative Biology 2013-03-05 Andrey Dovzhenok , Choongseok Park , Robert M. Worth , Leonid L. Rubchinsky

Neuropixels probes, initially developed for use in small animal models, have transformed basic neuroscience by enabling high-density, single-cell resolution recordings across multiple brain regions simultaneously. The recent development of…

Spiking Neural Networks (SNNs) hold great potential to realize brain-inspired, energy-efficient computational systems. However, current SNNs still fall short in terms of multi-scale temporal processing compared to their biological…

Neural and Evolutionary Computing · Computer Science 2024-08-28 Xinyi Chen , Jibin Wu , Chenxiang Ma , Yinsong Yan , Yujie Wu , Kay Chen Tan

We study noisy calcium imaging data, with a focus on the classification of spike traces. As raw traces obscure the true temporal structure of neuron's activity, we performed a tuned filtering of the calcium concentration using two methods:…

Neurons and Cognition · Quantitative Biology 2024-09-17 Arianna Burzacchi , Nicoletta D'Angelo , David Payares-Garcia , Jorge Mateu

Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…

Bidirectional deep brain stimulation (bdDBS) devices capable of recording differential local field potentials (dLFP) enable neural recordings alongside clinical therapy. Efforts to identify objective signals of various brain disorders, or…

Monitoring respiration parameters such as respiratory rate could be beneficial to understand the impact of training on equine health and performance and ultimately improve equine welfare. In this work, we compare deep learning-based methods…

Signal Processing · Electrical Eng. & Systems 2025-08-05 Jeanne I. M. Parmentier , Rhana M. Aarts , Elin Hernlund , Marie Rhodin , Berend Jan van der Zwaag

In this work, we propose to catch the complexity of the membrane potential's dynamic of a motoneuron between its spikes, taking into account the spikes from other neurons around. Our approach relies on two types of data: extracellular…

Statistics Theory · Mathematics 2021-08-03 Anna Bonnet , Charlotte Dion , François Gindraud , Sarah Lemler

We present two Bayesian procedures to infer the interactions and external currents in an assembly of stochastic integrate-and-fire neurons from the recording of their spiking activity. The first procedure is based on the exact calculation…

Machine Learning · Statistics 2011-02-28 Remi Monasson , Simona Cocco

Neurophysiological time series, such as electromyographic signal and intracortical recordings, are typically composed of many individual spiking sources, the recovery of which can give fundamental insights into the biological system of…

Machine Learning · Computer Science 2021-10-18 Alexander Kenneth Clarke , Dario Farina

The electroencephalogram, a type of non-invasive-based brain signal that has a user intention-related feature provides an efficient bidirectional pathway between user and computer. In this work, we proposed a deep learning framework based…

Human-Computer Interaction · Computer Science 2020-12-08 Byoung-Hee Kwon , Byeong-Hoo Lee , Ji-Hoon Jeong

Improved surgical skill is generally associated with improved patient outcomes, although assessment is subjective; labour-intensive; and requires domain specific expertise. Automated data driven metrics can alleviate these difficulties, as…

To obtain precisely controllable, robust as well as reproduceable memristor for efficient neuromorphic computing still very challenging. Molecular tailoring aims at obtaining the much more flexibly tuning plasticity has recently generated…

Mesoscale and Nanoscale Physics · Physics 2017-04-06 Zhiyong Wang , Laiyuan Wang , Masaru Nagai , Linghai Xie , Haifeng Ling , Qi Li , Ying Zhu , Tengfei Li , Mingdong Yi , Naien Shi , Wei Huang

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

Cochlear implants(CIs) are arguably the most successful neural implant, having restored hearing to over one million people worldwide. While CI research has focused on modeling the cochlear activations in response to low-level acoustic…

Neural and Evolutionary Computing · Computer Science 2024-07-31 Cynthia R. Steinhardt , Menoua Keshishian , Nima Mesgarani , Kim Stachenfeld

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…

Neurons and Cognition · Quantitative Biology 2026-04-01 Siyuan Du , Siyi Li , Shuwei Bai , Ang Li , Haolin Li , Mingqing Xiao , Yang Pan , Dongsheng Li , Weidi Xie , Yanfeng Wang , Ya Zhang , Chencheng Zhang , Jiangchao Yao

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

Machine Learning · Computer Science 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Sensory neurons are often described in terms of a receptive field, that is, a linear kernel through which stimuli are filtered before they are further processed. If information transmission is assumed to proceed in a feedforward cascade,…

Neurons and Cognition · Quantitative Biology 2015-03-11 Eugenio Urdapilleta , Inés Samengo

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

Neurons and Cognition · Quantitative Biology 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

The advent of advanced neuronal interfaces offers great promise for linking brain functions to electronics. A major bottleneck in achieving this is real-time processing of big data that imposes excessive requirements on bandwidth, energy…

Emerging Technologies · Computer Science 2015-07-27 Isha Gupta , Alexantrou Serb , Ali Khiat , Ralf Zeitler , Stefano Vassanelli , Themistoklis Prodromakis