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Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective…

Estimating a covariance matrix is central to high-dimensional data analysis. Empirical analyses of high-dimensional biomedical data, including genomics, proteomics, microbiome, and neuroimaging, among others, consistently reveal strong…

Methodology · Statistics 2024-12-05 Yifan Yang , Chixiang Chen , Shuo Chen

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

Machine Learning · Computer Science 2016-02-25 Daniele Ramazzotti

One of the important techniques of Data mining is Classification. Many real world problems in various fields such as business, science, industry and medicine can be solved by using classification approach. Neural Networks have emerged as an…

Machine Learning · Computer Science 2011-10-13 K. Usha Rani

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

Computers and Society · Computer Science 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss…

Quantitative Methods · Quantitative Biology 2023-02-14 Bruce P. Ayati , Glenn F. Webb , Alexander R. A. Anderson

Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

Machine Learning · Statistics 2018-11-21 Nora K. Speicher , Nico Pfeifer

While performing knowledge-intensive tasks of professional nature, the knowledge workers need to access and process large volume of information. Apart from the quantity, they also require that the information received is of high quality in…

Human-Computer Interaction · Computer Science 2009-12-03 Arijit Laha

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

Often the rows (cases, objects) of a dataset have weights. For instance, the weight of a case may reflect the number of times it has been observed, or its reliability. For analyzing such data many rowwise weighted techniques are available,…

Computation · Statistics 2024-07-08 Peter J. Rousseeuw

An Electronic Health Record (EHR) system must enable efficient availability of meaningful, accurate and complete data to assist improved clinical administration through the development, implementation and optimisation of clinical pathways.…

Computers and Society · Computer Science 2018-02-05 P. Vimalachandran , H. Wang , Y. Zhang , B. Heyward , F. Whittaker

Electronic health records (EHRs) provide comprehensive patient data which could be better used to enhance informed decision-making, resource allocation, and coordinated care, thereby optimising healthcare delivery. However, in mental…

eHealth technologies have been increasingly used to foster proactive self-management skills for patients with chronic diseases. However, it is challenging to provide each user with their desired support due to the dynamic and diverse nature…

Human-Computer Interaction · Computer Science 2023-12-20 Wei Wang , Hourieh Khalajzadeh , Anuradha Madugalla , Jennifer Mcintosh , Humphrey Obie

A prototype for a web application was designed and implemented as a guide to be used by clinicians when designing the best drug therapy for a specific cancer patient, given biological data derived from the patients tumor tissue biopsy. A…

Molecular Networks · Quantitative Biology 2014-05-15 Elinor Velasquez , Jorge Soto-Andrade , Ben Bongalon

Providing a customized support for the OLAP brings tremendous challenges to the OLAP technology. Standing at the crossroads of the preferences and the data warehouse, two emerging trends are pointed out; namely: (i) the personalization and…

Databases · Computer Science 2015-06-01 Eya Ben Ahmed , Ahlem Nabli , Faïez Gargouri

Human medical data can be challenging to obtain due to data privacy concerns, difficulties conducting certain types of experiments, or prohibitive associated costs. In many settings, data from animal models or in-vitro cell lines are…

Data privacy refers to ensuring that users keep control over access to information, whereas data accessibility refers to ensuring that information access is unconstrained. Conflicts between privacy and accessibility of data are natural to…

Process mining in healthcare presents a range of challenges when working with different types of data within the healthcare domain. There is high diversity considering the variety of data collected from healthcare processes: operational…

We propose to improve medical decision making and reduce global health care costs by employing a free Internet-based medical information system with two main target groups: practicing physicians and medical researchers. After acquiring…

Computers and Society · Computer Science 2008-10-14 Axel Boldt , Michael Janich

Data organization is a difficult and essential component in cultural heritage applications. Over the years, a great amount of archaeological ceramic data have been created and processed by various methods and devices. Such ceramic data are…

Databases · Computer Science 2016-08-24 Aybükë Oztürk , Louis Eyango , Sylvie Yona Waksman , Stéphane Lallich , Jérôme Darmont