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A new approach for solving the optical inverse problem of quantitative photoacoustic tomography is introduced, which interpolates between the well-known diffusion approximation and a radiative transfer equation based model. The proposed…

Computational Physics · Physics 2025-09-09 David J. Chappell

We study the inverse source problem in photoacoustic tomography (PAT) for mixed data, which denote a weighted linear combination of the acoustic pressure and its normal derivative on an observation surface. We consider in particular the…

Analysis of PDEs · Mathematics 2022-07-06 Florian Dreier , Markus Haltmeier

We consider the reconstruction of the diffusion and absorption coefficients of the diffusion equation from the internal information of the solution obtained from the first step of the inverse photoacoustic tomography (PAT). In practice, the…

Analysis of PDEs · Mathematics 2021-09-22 Faouzi Triki , Qi Xue

A framework for reconstruction of optical diffusion and absorption coefficients in quantitative photoacoustic tomography is presented. This framework is based on a Tikhonov-type functional with a regularization term promoting sparsity of…

Optimization and Control · Mathematics 2024-02-01 Anwesa Dey , Alfio Borzi , Souvik Roy

This work is concerned with uncertainty quantification problems for image reconstructions in quantitative photoacoustic imaging (PAT), a recent hybrid imaging modality that utilizes the photoacoustic effect to achieve high-resolution…

Numerical Analysis · Mathematics 2018-12-10 Kui Ren , Sarah Vallélian

Thermoacoustic tomography (TAT) is an imaging modality based on the thermoacoustic effect. In TAT, a short microwave or radio wave pulse is directed to the imaged target. The energy of the electromagnetic pulse is absorbed depending on the…

Computational Physics · Physics 2025-11-11 Teemu Sahlström , Tanja Tarvainen

Photoacoustic tomography (PAT) is a hybrid medical imaging technique that offer high contrast and a high spatial resolution. One challenging mathematical problem associated with PAT is reconstructing the initial pressure of the wave…

Numerical Analysis · Mathematics 2024-07-16 Gyeongha Hwang , Gihyeon Jeon , Sunghwan Moon , Dabin Park

Quantitative photoacoustic computed tomography (qPACT) is an emerging medical imaging modality that carries the promise of high-contrast, fine-resolution imaging of clinically relevant quantities like hemoglobin concentration and…

Medical Physics · Physics 2024-10-15 Evan Scope Crafts , Mark A. Anastasio , Umberto Villa

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

We treat the stability issue for the three dimensional inverse imaging modality called Quantitative Photoacoustic Tomography. We provide universal choices of the illuminations which enable to recover, in a H\"older stable fashion, the…

Analysis of PDEs · Mathematics 2015-05-15 Giovanni Alessandrini , Michele Di Cristo , Elisa Francini , Sergio Vessella

The attenuation of ultrasound waves in photoacoustic and thermoacoustic imaging presents an important drawback in the applicability of these modalities. This issue has been addressed previously in the applied and theoretical literature, and…

Analysis of PDEs · Mathematics 2021-09-15 Benjamin Palacios

The reconstruction task in photoacoustic tomography can vary a lot depending on measured targets, geometry, and especially the quantity we want to recover. Specifically, as the signal is generated due to the coupling of light and sound by…

Medical Physics · Physics 2023-11-28 Andreas Hauptmann , Tanja Tarvainen

The inverse source problem arising in photoacoustic tomography and in several other coupled-physics modalities is frequently solved by iterative algorithms. Such algorithms are based on the minimization of a certain cost functional. In…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Andreas Hauptmann , Leonid Kunyansky , Jenni Poimala

This is the manuscript of the chapter for a planned Handbook of Mathematical Methods in Imaging that surveys the mathematical models, problems, and algorithms of the Thermoacoustic (TAT) and Photoacoustic (PAT) Tomography. TAT and PAT…

Analysis of PDEs · Mathematics 2011-10-04 Peter Kuchment , Leonid Kunyansky

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Standard photoacoustic tomography (PAT) provides data that consist of time-dependent signals governed by the wave equation, which are measured on an observation surface. In contrast, the measured data from the recently invented full-field…

Numerical Analysis · Mathematics 2024-06-10 Ngoc Do , Markus Haltmeier , Richard Kowar , Linh V. Nguyen , Robert Nuster

The standard approach for photoacoustic imaging with variable speed of sound is time reversal, which consists in solving a well-posed final-boundary value problem for the wave equation backwards in time. This paper investigates the…

Optimization and Control · Mathematics 2016-03-17 Zakaria Belhachmi , Thomas Glatz , Otmar Scherzer

Quantitative photoacoustic tomography aims at estimating optical parameters from photoacoustic images that are formed utilizing the photoacoustic effect caused by the absorption of an externally introduced light pulse. This optical…

Medical Physics · Physics 2020-10-02 Aleksi Leino , Tuomas Lunttila , Meghdoot Mozumder , Aki Pulkkinen , Tanja Tarvainen

We propose a model-based image reconstruction method for photoacoustic tomography(PAT) involving a novel form of regularization and demonstrate its ability to recover good quality images from significantly reduced size datasets. The…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Nadaparambil Aravindakshan Rejesh , Sandeep Kumar Kalva , Manojit Pramanik , Muthuvel Arigovindan

Photoacoustic tomography (PAT) is an emerging imaging modality that aims at measuring the high-contrast optical properties of tissues by means of high-resolution ultrasonic measurements. The interaction between these two types of waves is…

Analysis of PDEs · Mathematics 2021-07-27 Giovanni S. Alberti , Paolo Campodonico , Matteo Santacesaria